Genome Editing News and Research

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New software tool enables quick, easy deletion of DNA in living cells

Until recently, genomics was a "read-only" science, but scientists have developed a tool for quick and easy deletion of DNA in living cells.

3 Mar 2017

MSK researchers harness power of CRISPR/Cas9 to create more-potent CAR T cells

Researchers from Memorial Sloan Kettering Cancer Center have harnessed the power of CRISPR/Cas9 to create more-potent chimeric antigen receptor (CAR) T cells that enhance tumor rejection in mice.

23 Feb 2017

Researchers create novel model that reveals cellular, molecular events driving leukemia progression

Mount Sinai researchers have created a novel model that shows the step-by-step progression from normal blood cells to leukemia and its precursor diseases, creating replicas of the stages of the disease to test the efficacy of therapeutic interventions at each stage, according to a study to be published in Cell Stem Cell.

16 Feb 2017

IDT offers cost-effective and most complete spectrum of CRISPR genome editing systems

Reflecting its drive to provide innovative solutions to the genomics community, Integrated DNA Technologies (IDT) is the first genomics company to develop and bring to market a complete ribonucleoprotein-based Cpf1 CRISPR system.

2 Feb 2017

ACMG issues new Points to Consider statement on potential clinical application of genome editing

The American College of Medical Genetics and Genomics is weighing in on the genome editing/CRISPR debate with a new Points to Consider statement, "Genome Editing in Clinical Genetics."

29 Jan 2017

TSRI researchers develop first stable semisynthetic single-celled organism

Life’s genetic code has only ever contained four natural bases. These bases pair up to form two “base pairs”—the rungs of the DNA ladder—and they have simply been rearranged to create bacteria and butterflies, penguins and people. Four bases make up all life as we know it.

25 Jan 2017

CeMM scientists develop new method by integrating CRISPR genome editing with single-cell sequencing

Genome editing using CRISPR/Cas9 "gene scissors" is a powerful tool for biological discovery and for identifying novel drug targets.

19 Jan 2017

Orphan Disease Center establishes new initiative that focuses on ALS

The Orphan Disease Center in the Perelman School of Medicine at the University of Pennsylvania has established a new Program of Excellence for Motor Neuron Disease.

10 Jan 2017

Researchers develop first non-human primate X-SCID models using genome editing techniques

Researchers affiliated with the Kawasaki INnovation Gateway at SKYFRONT, have successfully generated the first ever non-human primate X-SCID models by using two genome editing techniques. The findings were published in Cell Stem Cell, July 2016.

3 Jan 2017

New IDT webinar to highlight benefits of using RNP complexes for efficient genome modifications

Integrated DNA Technologies will host an informative webinar entitled ‘Ribonucleoprotein delivery of CRISPR-Cas9 reagents for increased gene editing efficiency’ on December 14, 2016.

9 Dec 2016

Researchers uncover first ‘off-switches’ for better control of CRISPR/Cas9 gene editing

CRISPR/Cas9 genome editing is quickly revolutionizing biomedical research, but the new technology is not yet exact. The technique can inadvertently make excessive or unwanted changes in the genome and create off-target mutations, limiting safety and efficacy in therapeutic applications.

9 Dec 2016

Synthetic sgRNA for CRISPR genome editing

Chemically synthesized single guide RNA is the best way to do CRISPR genome editing. It is more pure than biological methods of creating guide RNAs, like in vitro transcription or plasmids. As a result, sgRNA leads to more consistency and higher quality.

8 Dec 2016

Penn researchers use CRISPR/Cas9 gene targeting approach to treat hemophilia B in mice

CRISPR/Cas9, a powerful genome editing tool, is showing promise for efficient correction of disease-causing mutations.

1 Dec 2016

MEMOIR can help read history and ‘family trees’ of cells

Researchers have developed a new method for reading the history and "family trees" of cells.

22 Nov 2016

Genome engineering-based methods pave way for new treatment of patients with sickle cell disease

A team of physicians and laboratory scientists has taken a key step toward a cure for sickle cell disease, using CRISPR-Cas9 gene editing to fix the mutated gene responsible for the disease in stem cells from the blood of affected patients.

12 Oct 2016

UTA research opens new doors for treatment of autoimmune diseases

Biologists at The University of Texas at Arlington have demonstrated that removing water molecules can deactivate caspase-3 enzymes, which opens new doors for treatment of autoimmune diseases like arthritis, which have been linked to overactive enzymes.

4 Oct 2016

Genome Editing News and Research

New software tool enables quick, easy deletion of DNA in living cells

MSK researchers harness power of CRISPR/Cas9 to create more-potent CAR T cells

Researchers create novel model that reveals cellular, molecular events driving leukemia progression

IDT offers cost-effective and most complete spectrum of CRISPR genome editing systems

ACMG issues new Points to Consider statement on potential clinical application of genome editing

TSRI researchers develop first stable semisynthetic single-celled organism

CeMM scientists develop new method by integrating CRISPR genome editing with single-cell sequencing

Orphan Disease Center establishes new initiative that focuses on ALS

Researchers develop first non-human primate X-SCID models using genome editing techniques

New IDT webinar to highlight benefits of using RNP complexes for efficient genome modifications

Researchers uncover first ‘off-switches’ for better control of CRISPR/Cas9 gene editing

Synthetic sgRNA for CRISPR genome editing

Penn researchers use CRISPR/Cas9 gene targeting approach to treat hemophilia B in mice

MEMOIR can help read history and ‘family trees’ of cells

Genome engineering-based methods pave way for new treatment of patients with sickle cell disease

UTA research opens new doors for treatment of autoimmune diseases

Synthego introduces CRISPRevolution synthetic sgRNA kit for fast, high-throughput gene editing

Novel DNA-altering method could lead to more treatment options for diseases

Kobe University researchers develop new technique for high-level genome editing operation

Scientists find new way to use CRISPR gene editing to help fix sickle cell disease

Genetics & Genomics - Second Edition eBook

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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