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Flies carry more disease-causing bacteria than suspected, study reveals

A new study, conducted by researchers from the Penn State Eberly College of Science, indicates that the disease-carrying ability of flies could be much greater than previously thought.

27 Nov 2017

Research findings will help identify genetic causes of brain disorders

New findings will help to identify the genetic causes of brain disorders: researchers at the Universities of Basel, Bonn and Cologne have presented a systematic catalog of specific variable locations in the genome that influence gene activity in the human hippocampus, as they report in the journal Nature Communications.

27 Nov 2017

Flies may be more potent pathogen carriers than previously thought

Flies can be more than pesky picnic crashers, they may be potent pathogen carriers, too, according to an international team of researchers.

25 Nov 2017

New approach can track how superbugs travel among and within health care facilities

Killer bacteria – ones that have out-evolved our best antibiotics -- may not go away anytime soon. But a new approach to tracking their spread could eventually give us a fighting chance to keep their death toll down.

23 Nov 2017

Leishmania genome study reveals the parasites adaptation to the environment

A new study, conducted by researchers from the Institut Pasteur in Paris and the Centre for Genomic Regulation (CRG) in Barcelona, have revealed that Leishmania adaptation is a consequence of reversible and frequent chromosomal amplifications.

23 Nov 2017

UVA researchers developing new tool to help cancer patients make complex care decisions

Researchers at the University of Virginia Cancer Center are developing a tool to help patients with prostate cancer better understand the potential risks and rewards of their treatment options. And that tool could ultimately benefit not just those patients but a broad spectrum of patients making complex care decisions based on their tumor's genomic information.

23 Nov 2017

Leishmania adaptation to environmental changes results from frequent chromosomal amplifications

Leishmaniasis is an important human and veterinary disease caused by Leishmania parasites that affect 12 million people in over 98 endemic countries. The disease is now emerging in Europe due to climate change and massive population displacement.

23 Nov 2017

3D folding of DNA during cardiomyocyte differentiation provides vital epigenetic mechanisms, study says

A new study conducted at the University of Freiburg suggests that three-dimensional (3D) folding of the DNA reorganizes itself during differentiation of pluripotent stem cells to cardiomyocytes.

22 Nov 2017

Research suggests genome's spatial organization as important switch for defining cell types

During differentiation of pluripotent stem cells to cardiomyocytes, the three-dimensional folding of the DNA reorganizes itself. This reorganization of the DNA architecture precedes and defines important epigenetic patterns.

22 Nov 2017

Anti-diabetic drug can enhance repair of UV-induced DNA damage in cells of ‘Moon children’

The destructive force of UV radiation on DNA molecules is only fully visible, when repair mechanisms fail: patients with the rare genetic disease Xeroderma pigmentosum - also known as 'Moon children' - develop inflammations upon exposure to only small amounts of sunlight, rough-surfaced growths and eventually skin cancer occurs often in early age.

21 Nov 2017

Researchers develop new tool to share clinico-genomic data

Researchers from Universidad Politécnica de Madrid have developed a new tool that provides standard and shared clinico-genomic data among European healthcare institutions.

20 Nov 2017

KAIST researchers identify principles of gene network for colon tumorigenesis

The principles of the gene network for colon tumorigenesis have been identified by a KAIST research team. The principles will be used to find the molecular target for effective anti-cancer drugs in the future. Further, this research gained attention for using a systems biology approach, which is an integrated research area of IT and BT.

20 Nov 2017

Gene editing within a living person for the first time

Genetic editing has been performed in the laboratory until now. Living cells within Petri-dishes have been put under the microscope while gene editing tools such as CRISPR were used to cut, nick and replace parts of the DNA or genome that is defective with bits of DNA that is correct in its sequence. Now doctors in California have attempted to edit cells within a living person.

19 Nov 2017

Leaf-eating ability of beetle largely due to bacteria inside the insect

A leaf-eating beetle has evolved a symbiotic relationship with bacteria that allows the insect to break down pectin -- part of a plant's cell wall that is indigestible to most animals.

17 Nov 2017

University of Bristol awarded grant to reduce antibacterial drug resistance in Thailand

The University of Bristol has been awarded a grant by the UK Research Councils and the Department of Health to lead an inter-disciplinary research project to tackle the growing threat of antibacterial drug resistance in Thailand.

16 Nov 2017

CRISPR shows potential to reduce diseases spread by mosquitoes

Research at the University of California, Riverside, have shown that it is possible for transgenic mosquitos to stably express the Cas9 enzyme in their germline. Cas9 addition will allow the utilization of the CRISPR gene editing tool to carry out efficient and highly targeted changes to the DNA of the mosquitoes.

16 Nov 2017

Genetic diversity of tumor tissues can be barrier to precision medicine in gastric and esophageal cancers

A new study focused on describing genetic variations within a primary tumor, differences between the primary and a metastatic branch of that tumor, and additional diversity found in tumor DNA in the blood stream could help physicians make better treatment choices for patients with gastric and esophageal adenocarcinoma.

15 Nov 2017

Study identifies molecular pathway critical to development of fibrosis

A study led by investigators at Massachusetts General Hospital and University Health Network in Toronto has identified a molecular pathway that appears to be critical to the development of fibrosis - scarring and excessive tissue deposition that result from abnormal healing responses and can compromise the function of vital organs.

15 Nov 2017

MGH researchers develop potential alternative to gadolinium-based MRI contrast agents

A team of Massachusetts General Hospital researchers has developed a potential alternative to gadolinium-based contrast agents (GBCAs) for magnetic resonance imaging.

15 Nov 2017

UCR researchers develop transgenic mosquitoes to help reduce spread of infectious diseases

Researchers at the University of California, Riverside have developed transgenic mosquitoes that stably express the Cas9 enzyme in their germline. The addition of Cas9 will enable the use of the CRISPR gene editing tool to make efficient, targeted changes to the mosquitoes' DNA.

14 Nov 2017

Genomic News and Research

Flies carry more disease-causing bacteria than suspected, study reveals

Research findings will help identify genetic causes of brain disorders

Flies may be more potent pathogen carriers than previously thought

New approach can track how superbugs travel among and within health care facilities

Leishmania genome study reveals the parasites adaptation to the environment

UVA researchers developing new tool to help cancer patients make complex care decisions

Leishmania adaptation to environmental changes results from frequent chromosomal amplifications

3D folding of DNA during cardiomyocyte differentiation provides vital epigenetic mechanisms, study says

Research suggests genome's spatial organization as important switch for defining cell types

Anti-diabetic drug can enhance repair of UV-induced DNA damage in cells of ‘Moon children’

Researchers develop new tool to share clinico-genomic data

KAIST researchers identify principles of gene network for colon tumorigenesis

Gene editing within a living person for the first time

Leaf-eating ability of beetle largely due to bacteria inside the insect

University of Bristol awarded grant to reduce antibacterial drug resistance in Thailand

CRISPR shows potential to reduce diseases spread by mosquitoes

Genetic diversity of tumor tissues can be barrier to precision medicine in gastric and esophageal cancers

Study identifies molecular pathway critical to development of fibrosis

MGH researchers develop potential alternative to gadolinium-based MRI contrast agents

UCR researchers develop transgenic mosquitoes to help reduce spread of infectious diseases

Genetics & Genomics - Second Edition eBook

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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