Genomic News and Research

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Research challenges the evolutionary paradigm that continuous alterations occur during the course of genome evolution

Researchers report today that regions of the human genome have been hotspots for acquiring duplicated DNA sequences - but only at specific time-points during evolution.

16 Jun 2005

Jumping genes help detemine uniqueness of individual brains

Scientists at the Salk Institute for Biological Studies may have found one explanation for the puzzling variety in brain organization and function: mobile elements, pieces of DNA that can jump from one place in the genome to another, randomly changing the genetic information in single brain cells.

15 Jun 2005

New technology developed at Cornell University could make it just as easy to identify genes

A supermarket checkout computer can identify thousands of different items by scanning the tiny barcode printed on the package. New technology developed at Cornell University could make it just as easy to identify genes, pathogens, illegal drugs and other chemicals of interest by tagging them with color-coded probes made out of synthetic tree-shaped DNA.

14 Jun 2005

If a dividing cell's activity is a pop song, then the same process in an immune cell is an extended-play dance remix

The basics of cell division are the same in both, but there's a heck of a lot more going on in immune cells, Johns Hopkins scientists have discovered.

10 Jun 2005

Statisticians learn how to analyze huge quantities of genetic data

In a conceptual breakthrough, a team of researchers led by statisticians at the Harvard School of Public Health (HSPH) has figured out how to analyze huge quantities of genetic data, surpassing the capabilities of traditional techniques and speeding the quest for understanding the genetic basis of complex diseases such as asthma and diabetes.

6 Jun 2005

Research findings suggest new treatment strategies for patients with cystic fibrosis

Cells sent to fight infections in the lungs of cystic fibrosis patients actually enhance the development of permanent bacterial infections, according to researchers at National Jewish Medical and Research Center.

3 Jun 2005

Disease progression model of pancreatic cancer developed

Building on previous work, researchers at the University of Pennsylvania School of Medicine have developed an animal model of pancreatic cancer that closely mimics disease progression in humans. From this, they hope to develop new treatments for this deadly disease.

20 May 2005

Researchers to explore genome of disease-fighting fungus

A team of Texas Agricultural Experiment Station scientists will soon begin genome sequencing a disease-fighting fungus used to protect crops, which has implications for both agriculture and the pharmaceutical industry.

15 May 2005

Simple and efficient method for creation of novel protein functions in an existing protein scaffold

By designing a molecular bridge, scientists at the University of Illinois at Urbana-Champaign have forged a successful pathway through a complex ocean of barriers: They've changed the function of a protein using a co-evolution approach.

8 May 2005

Alarming trends in sexually transmitted diseases (STDs) among America's young people

A study by ASHA, sponsored by Roche Diagnostics of Indianapolis, Indiana is being released in conjunction with April's STD Awareness Month and demonstrates that the incident rate of STDS in youth (ages 15-24) have increased dramatically in recent years.

12 Apr 2005

Fifteen-year hunt uncovers gene behind pseudothalidomide syndrome

A team of scientists from Colombia, the United States and elsewhere has successfully completed a 15-year-plus search for the genetic problems behind the very rare Roberts syndrome, whose physical manifestations often include cleft lip and palate and shortened limbs that resemble those of babies whose mothers took thalidomide during pregnancy.

11 Apr 2005

Findings will stir new research in bacterial evolution

Bacteria acquired up to 90 percent of their genetic material from distantly related bacteria species, according to new research from The University of Arizona in Tucson.

7 Apr 2005

Researchers set a new standard in the design and engineering of nuclear hormone receptor-based genetic on-off switches

Researchers at the University of Illinois at Urbana-Champaign have set a new standard in the design and engineering of nuclear hormone receptor-based genetic on-off switches, without causing new problems or aggravating existing ones.

7 Apr 2005

Genomic DNA provides clues to new advances in cancer diagnostics

Researchers at the University of Illinois at Chicago have identified a method of assessing the malignant potential of cells based on the sensitivity of cellular DNA to enzyme digestion.

22 Mar 2005

ParAllele BioScience announces key patent issuance

ParAllele BioScience has announced the issuance by the U.S. Patent Office of a key patent (6,858,412) covering its Molecular Inversion Probe (MIP) technology. The patent is owned by Stanford University and is exclusively licensed to ParAllele.

21 Mar 2005

Genomic analysis may one day be a primary diagnostic tool for physicians deciding on a course of treatment for trauma

The researchers showed that state-of-the-art techniques for rapidly analyzing changes in activity of all human genes will likely produce useful insights into the health of critically ill patients. The findings, which are available online and will be published in the March 29 issue of the Proceedings of the National Academy of Sciences, make it possible for physicians to begin answering important questions about critical care through genomic analysis.

21 Mar 2005

DNA weak links may provide clues to cancer biology

The chromosomes of mammals, including humans, contain regions that are particularly prone to breaking under conditions of stress and in cancer. Now, new research by geneticists at Duke University Medical Center finds that yeast cells also contain such weak links in DNA and begins to reveal the molecular characteristics of these links that might help to explain them.

13 Mar 2005

Genetic examinations of trauma, burn victims produce consistent results

A genetic tool with the potential to identify which trauma and burn patients are most likely to become seriously ill has worked consistently in a wide range of experimental clinical settings - an important hurdle to overcome before the method is routinely used in emergency rooms and intensive care units.

7 Mar 2005

DNA ejection from single phage particles

Studying phage, a primitive class of virus that infects bacteria by injecting its genomic DNA into host cells, researchers have gained insight into the driving force behind this poorly understood injection process, which has been proposed in the past to occur through the release of pressure accumulated within the viral particle itself.

7 Mar 2005

Air Genome Project to sample air using whole genome shotgun sequencing

The J. Craig Venter Institute is launching a pilot project to better understand the diversity of microbes in urban air. In addition to more deeply characterizing the microbes we breathe every day, researchers anticipate that the results will provide information vital to designing systems that detect potentially dangerous biological substances in the air.

7 Mar 2005

Genomic News and Research

Research challenges the evolutionary paradigm that continuous alterations occur during the course of genome evolution

Jumping genes help detemine uniqueness of individual brains

New technology developed at Cornell University could make it just as easy to identify genes

If a dividing cell's activity is a pop song, then the same process in an immune cell is an extended-play dance remix

Statisticians learn how to analyze huge quantities of genetic data

Research findings suggest new treatment strategies for patients with cystic fibrosis

Disease progression model of pancreatic cancer developed

Researchers to explore genome of disease-fighting fungus

Simple and efficient method for creation of novel protein functions in an existing protein scaffold

Alarming trends in sexually transmitted diseases (STDs) among America's young people

Fifteen-year hunt uncovers gene behind pseudothalidomide syndrome

Findings will stir new research in bacterial evolution

Researchers set a new standard in the design and engineering of nuclear hormone receptor-based genetic on-off switches

Genomic DNA provides clues to new advances in cancer diagnostics

ParAllele BioScience announces key patent issuance

Genomic analysis may one day be a primary diagnostic tool for physicians deciding on a course of treatment for trauma

DNA weak links may provide clues to cancer biology

Genetic examinations of trauma, burn victims produce consistent results

DNA ejection from single phage particles

Air Genome Project to sample air using whole genome shotgun sequencing

Genetics & Genomics - Second Edition eBook

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