Glioblastoma News and Research

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Glioblastoma is the most aggressive and malignant form of glioma, a type of primary brain cancer. Surgery is often used to treat gliomas, along with radiation. However, since surgery and radiation fail to cure the disease, doctors may turn to additional radiation or chemotherapy. In early stages glioblastoma tumors often grow without symptoms and therefore can become quite large before symptoms arise. When the tumor becomes symptomatic, tumor growth is usually very rapid and is accompanied by altered brain function, and if left untreated the disease becomes lethal. Although primary treatment is often successful in temporarily stopping the progression of the tumor, glioblastomas almost always recur and become lethal.

New tool for noninvasive imaging can help illuminate hard-to-access brain structures

Talk about a bright idea: Thanks to chemists at Rice University and Stanford University, lighting up the brain is no longer just a figure of speech.

17 Jan 2023

Researchers develop a computational model to accurately predict lethal brain tumor growth

Researchers at the University of Waterloo have created a computational model to predict the growth of deadly brain tumors more accurately.

16 Jan 2023

New cooling strategy could prevent the growth of glioblastoma

Cooling brain tumor cells to stop them from dividing without killing healthy cells extended the survival of glioblastoma (GBM) animal models dramatically in a study led by a UT Southwestern resident.

12 Jan 2023

Researchers show how liver cancer cells hijack circadian clock machinery to divide and spread

The most common type of liver cancer, hepatocellular carcinoma (HCC), is already the third leading cause of cancer-related deaths globally-;and cases are on the rise, both in the U.S. and worldwide.

6 Jan 2023

New dual-action, cancer-killing vaccine tested in an advanced mouse model of glioblastoma

Scientists are harnessing a new way to turn cancer cells into potent, anti-cancer agents. In the latest work from the lab of Khalid Shah, MS, PhD, at Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, investigators have developed a new cell therapy approach to eliminate established tumors and induce long-term immunity, training the immune system so that it can prevent cancer from recurring.

4 Jan 2023

Phase I clinical trial of PAC-1 in patients with end-stage cancers shows promising results

A phase I clinical trial of PAC-1, a drug that spurs programmed cell death in cancer cells, found only minor side effects in patients with end-stage cancers.

22 Dec 2022

CARxALL clinical trial approved to evaluate CAR-T technology for patients with T-cell leukemia subtype

The Spanish Agency of Medicines and Medical Products (AEMPS) has approved the CARxALL clinical trial led by the company OneChain Immunotherapeutics (OCI).

21 Dec 2022

Using 3D patient tumor avatars to guide cancer treatment decisions

At any time, most cancer patients are receiving a treatment that does not significantly benefit them while enduring bodily and financial toxicity.

20 Dec 2022

Phenotypic plasticity may allow cancer cells to evade standard therapy

Glioblastomas (GBMs) are incurable brain tumors with a prognosis of about one-and-a half years on average. They are highly resistant to treatment and have defied all attempts at precision therapy.

20 Dec 2022

Research: Patient's race may influence recommendations for surgical resection of brain tumors

Published in The Lancet, University of Minnesota Medical School researchers found a patient's race may influence recommendations for surgical removal of brain tumors.

15 Dec 2022

Discovery of three new brain tumor subtypes could help to identify novel, effective therapies

Research lead by RCSI University of Medicine and Health Sciences has discovered three new subtypes of brain tumor which could help to identify new and effective therapies.

6 Dec 2022

Largest machine learning effort securely aggregates data from brain scans of glioblastoma patients

Researchers at Penn Medicine and Intel Corporation led the largest-to-date global machine learning effort to securely aggregate knowledge from brain scans of 6,314 glioblastoma (GBM) patients at 71 sites around the globe and develop a model that can enhance identification and prediction of boundaries in three tumor sub-compartments, without compromising patient privacy.

6 Dec 2022

Understanding the genetics of healthy brain cells to target vulnerabilities in glioblastomas

Understanding how cancer cells evolve from healthy brain cells and evade treatment could open up potential new drug therapies for glioblastomas, one of the most common and lethal brain cancers, new research has revealed.

29 Nov 2022

Over 440 SCI articles published! BGI’s cancer genetics and cell research fuels innovation

BGI has currently published over 440 SCI (Science Citation Index) papers in the field of cancer research, with a cumulative impact factor of over 4,000 points.

From BGI Genomics 23 Nov 2022

Rice bioengineer receives support for brain cancer research

Kevin McHugh, an assistant professor of bioengineering at Rice University's George R. Brown School of Engineering, has earned a Distinguished Scientist Award for 2022 from The Sontag Foundation, which helps launch the careers of scientists expected to make a significant impact in the fight against brain cancer.

21 Nov 2022

Glioblastoma News and Research

Further Reading

New tool for noninvasive imaging can help illuminate hard-to-access brain structures

Researchers develop a computational model to accurately predict lethal brain tumor growth

New cooling strategy could prevent the growth of glioblastoma

Researchers show how liver cancer cells hijack circadian clock machinery to divide and spread

New dual-action, cancer-killing vaccine tested in an advanced mouse model of glioblastoma

Phase I clinical trial of PAC-1 in patients with end-stage cancers shows promising results

CARxALL clinical trial approved to evaluate CAR-T technology for patients with T-cell leukemia subtype

Using 3D patient tumor avatars to guide cancer treatment decisions

Phenotypic plasticity may allow cancer cells to evade standard therapy

Research: Patient's race may influence recommendations for surgical resection of brain tumors

Discovery of three new brain tumor subtypes could help to identify novel, effective therapies

Largest machine learning effort securely aggregates data from brain scans of glioblastoma patients

Understanding the genetics of healthy brain cells to target vulnerabilities in glioblastomas

Over 440 SCI articles published! BGI’s cancer genetics and cell research fuels innovation

Rice bioengineer receives support for brain cancer research

New approach for delivering medication across the blood-brain barrier to treat brain tumors

Pt(IV)-conjugated drug-delivery system shows efficacy in glioblastoma therapy

Researchers take a cue from viruses to make glioblastoma more vulnerable to treatment

Researchers propose origin-of-life molecule as therapeutic target for tailored cancer therapies

Novel nanotechnology triggers potent therapeutic anti-tumor immune responses against multiple cancers

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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