Glioblastoma News and Research

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Glioblastoma is the most aggressive and malignant form of glioma, a type of primary brain cancer. Surgery is often used to treat gliomas, along with radiation. However, since surgery and radiation fail to cure the disease, doctors may turn to additional radiation or chemotherapy. In early stages glioblastoma tumors often grow without symptoms and therefore can become quite large before symptoms arise. When the tumor becomes symptomatic, tumor growth is usually very rapid and is accompanied by altered brain function, and if left untreated the disease becomes lethal. Although primary treatment is often successful in temporarily stopping the progression of the tumor, glioblastomas almost always recur and become lethal.

Researchers identify biomarkers that could be targets for novel drugs to treat glioblastoma

Biomarkers that could be targets for novel drugs to treat glioblastoma brain tumors have been identified by investigators at Georgetown Lombardi Comprehensive Cancer Center, providing hope for a cancer that is highly lethal.

22 Jun 2022

Conceptual framework to examine the patterns of copy number alterations in human cancer

A new study published in Nature presented a conceptual framework to examine the patterns of copy number alterations in human cancer.

17 Jun 2022

Researchers identify a signature of three genes linked to positive response to blood cancer therapy

Mount Sinai researchers have for the first time identified genes that predict a good response to a vital new therapy for a blood cancer that can have serious side effects for some patients.

16 Jun 2022

Combination of three technologies makes potential treatment effective against aggressive brain tumor

A drug carrier able to reach the brain, bind to an aggressive type of tumor called glioblastoma multiforme, and release a chemotherapeutic agent has been tested for the first time by Brazilian researchers.

15 Jun 2022

Treatment with immunity-boosting protein enhances the function of CAR-T cells in fighting blood cancers

Advances in cellular immunotherapy that spur genetically modified T cells to attack cancer cells have revolutionized the treatment of certain blood cancers.

13 Jun 2022

New molecule kills a broad spectrum of hard-to-treat cancers

A new molecule synthesized by a University of Texas at Dallas researcher kills a broad spectrum of hard-to-treat cancers, including triple-negative breast cancer, by exploiting a weakness in cells not previously targeted by other drugs.

10 Jun 2022

Proteomic analysis of 2002 tumors reveals 11 distinct pan-cancer molecular subtypes

A new study that analyzed protein levels in 2,002 primary tumors from 14 tissue-based cancer types identified 11 distinct molecular subtypes, providing systematic knowledge that greatly expands a searchable online database that has become a go-to platform for cancer data analysis by users worldwide.

10 Jun 2022

New compound shows promise to kill a range of hard-to-treat cancer types

A compound, developed by a team including scientists from The University of Texas Health Science Center at San Antonio, kills a range of hard-to-treat cancer types in petri dishes and animal models by targeting a previously unexploited vulnerability, a new study reports.

2 Jun 2022

Novel photonic technology could enable fluorescent sensors to track molecules deep inside the body

Fluorescent sensors, which can be used to label and image a wide variety of molecules, offer a unique glimpse inside living cells.

30 May 2022

New MRI nanotechnology designed to precisely image aggressive brain tumors

A novel technology designed to precisely image aggressive brain cancers and guide treatment is being developed by the University of South Australia and Australian cancer diagnostic company, Ferronova, potentially helping thousands of people who are diagnosed with the deadly condition each year.

12 May 2022

Rutgers study identifies key protein for brain stem cell longevity

A receptor that was first identified as necessary for insulin action, that also is located on the neural stem cells found deep in the brains of mice, is pivotal for brain stem cell longevity, according to a Rutgers study, a finding that has important implications for brain health and future therapies for brain disorders.

11 May 2022

Research suggests a new approach to treating Glioblastoma Multiforme in adults

Findings from a seven-year research project suggests that there could be a new approach to treating one of the most common and devasting forms of brain cancer in adults - Glioblastoma Multiforme (GBM).

9 May 2022

Novel magnetic therapy complements chemotherapy to enhance breast cancer treatment outcomes

Breast cancer is the leading cause of cancer-associated death for women worldwide. While chemotherapy is the mainstream treatment for breast cancer, more than 50% of women undergoing chemotherapy will experience at least one chemotherapy-related adverse side effect.

3 May 2022

Johns Hopkins scientists receive $7.8 million funding from Break Through Cancer

The Johns Hopkins Kimmel Cancer Center and the Departments of Gynecology/Obstetrics, Neurosurgery and Pathology have been awarded more than $7.8 million for novel, multicenter projects designed to intercept and find cures for several deadly cancers, including pancreatic cancer, ovarian cancer, and the brain cancer known as glioblastoma.

26 Apr 2022

MD Anderson awarded more than $10 million in grants to support collaborative cancer research

The University of Texas MD Anderson Cancer Center was awarded more than $10 million in grants to support collaborative research teams working to advance novel interception and treatment strategies that will improve outcomes for several cancer types with the greatest unmet need, including pancreatic cancer, ovarian cancer and glioblastoma (GBM).

19 Apr 2022

A comprehensive rule book for the design of safe and efficient therapeutic cells

Therapies based on engineered immune cells have recently emerged as a promising approach in the treatment of cancer.

15 Apr 2022

Scientists discover differences in interaction of T-cells within tumor microenvironments

A team led by Northwestern Medicine investigators has discovered differences in the distribution and interaction of T-cells within the microenvironment of different regions of both brain tumors and brain metastases, according to findings published in the journal JCI Insight.

14 Apr 2022

Harnessing electricity to treat certain types of cancer

Electricity has formed the basis of many aspects of the modern world, from providing reliable sources of light to powering home appliances and computers.

12 Apr 2022

Novel therapy advances to clinical trial for the treatment of glioblastoma

A novel therapy studied at the Medical College of Wisconsin (MCW) Cancer Center has led to a clinical trial for the treatment of glioblastoma, a rare and aggressive form of brain cancer, yet the most common primary brain tumor in adults.

10 Apr 2022

City of Hope's late-breaking clinical trial data to be presented at AACR

Researchers at City of Hope, one of the largest cancer research and treatment organizations in the United States, will present late-breaking and clinical trial findings at this year's American Association for Cancer Research Annual Meeting, which begins today.

8 Apr 2022