Glioma News and Research

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Glioma is a cancer of the brain that begins in glial cells (cells that surround and support nerve cells).

Heidelberg neuropathologists detect astrocytomas that can deactivate the "death receptor"

Malignant brain tumors often fail to respond to promising new medication. Researchers in Heidelberg have discovered a mechanism and a tumor marker for the development of this resistance. A "death receptor" can possibly provide information as to how great the chances of success are for chemotherapy. At the same time, it offers a new approach for promising brain tumor therapy.

2 Sep 2009

Altered gene network interaction plays an important role in brain tumors

The interaction between a network of altered genes appears to play an important role in the development and progression of brain tumors, according to a study in the July 15 issue of JAMA.

1 Sep 2009

Elevated levels of GLI1 protein linked to unfavorable prognosis and progressive stages in human breast cancer

Elevated levels of GLI1 (glioma-associated oncogene homolog 1) protein in human breast cancer are associated with unfavorable prognosis and progressive stages of disease. Researchers writing in the open access journal BMC Cancer found increased expression of GLI1 in samples taken from more advanced and less survivable tumors.

25 Aug 2009

Research study links partial epilepsy to the disruption of brain development during early childhood

A form of partial epilepsy associated with auditory and other sensory hallucinations has been linked to the disruption of brain development during early childhood, according to a study led by researchers at Beth Israel Deaconess Medical Center (BIDMC).

24 Aug 2009

Antigenics’ Oncophage cancer vaccine trial starts enrolling patients

Antigenics Inc. (NASDAQ:AGEN) today announced that the Brain Tumor Research Center at the University of California, San Francisco, has begun enrolling patients into a Phase 2 clinical trial of Oncophage (vitespen) in combination with the standard of care - radiation therapy plus Temodar (temozolomide) - for newly diagnosed glioma patients.

13 Aug 2009

DNA alterations on human chromosome 9 linked to glioblastoma

Mayo Clinic researchers and colleagues at the University of California San Francisco (UCSF) have found a connection between DNA alterations on human chromosome 9 and aggressive brain cancer known as glioblastoma. The findings are reported in the current online issue of Nature Genetics.

5 Jul 2009

Glioblastoma may originate in neural stem cells

University of Michigan scientists have found that a deficiency in a key tumor suppressor gene in the brain leads to the most common type of adult brain cancer. The study, conducted in mice that mimic human cancer, points the way to more effective future treatments and a way to screen for the disease early.

1 Jun 2009

Computer model predicts how brain tumors grow and evolve

Researchers from Brown University and other institutions have developed a computational computer model of how brain tumors grow and evolve.

18 May 2009

New findings on how lithium may help radiation target cancer

Vanderbilt-Ingram Cancer Center investigators have uncovered a mechanism that helps explain how lithium, a drug widely used to treat bipolar mood disorder, also protects the brain from damage that occurs during radiation treatments.

4 May 2009

$Hypofractionated stereotactic radiotherapy beneficial for recurrent low-grade glioma$

Hypofractionated stereotactic radiotherapy beneficial for recurrent low-grade glioma

Hypofractionated stereotactic radiotherapy was well-tolerated and improved symptoms in patients with recurrent low-grade glioma, according to researchers from the Kimmel Cancer Center at Jefferson.

22 Apr 2009

New drug to target tumor cells and blood vessels

Researchers at the University of Southern California have identified a new drug compound that appears to target tumor cells and surrounding blood vessels without the negative side effects typically associated with Cox-2 inhibitors.

21 Apr 2009

New drug to target tumor cells and blood vessels

21 Apr 2009

Discovery of possible way to block the spread of deadly brain tumors

Researchers at the Translational Genomics Research Institute (TGen) may have found a way to stop the often-rapid spread of deadly brain tumors.

20 Apr 2009

New imaging analysis method predicts brain tumor survival

As early as one week after beginning treatment for brain tumors, a new imaging analysis method was able to predict which patients would live longer, researchers from the University of Michigan Comprehensive Cancer Center have found.

20 Apr 2009

Avastin safe and effective at delaying tumor progression

The use of Avastin alone to treat a subgroup of recurrent Grade 3 brain tumors showed it was safe and effective at delaying tumor progression, according to a retrospective study of 22 patients conducted by a researcher at the Seattle Cancer Care Alliance.

6 Apr 2009

Advances in stem cell research

Scientists at The University of Texas Health Science Center at Houston are on the forefront of stem cell research, developing novel therapies designed to generate heart cells, repair traumatic lung injuries, grow new bone and stanch the spread of cancer cells.

8 Mar 2009

Glioma News and Research

Further Reading

Heidelberg neuropathologists detect astrocytomas that can deactivate the "death receptor"

Altered gene network interaction plays an important role in brain tumors

Elevated levels of GLI1 protein linked to unfavorable prognosis and progressive stages in human breast cancer

Research study links partial epilepsy to the disruption of brain development during early childhood

Antigenics’ Oncophage cancer vaccine trial starts enrolling patients

DNA alterations on human chromosome 9 linked to glioblastoma

Glioblastoma may originate in neural stem cells

Computer model predicts how brain tumors grow and evolve

New findings on how lithium may help radiation target cancer

Hypofractionated stereotactic radiotherapy beneficial for recurrent low-grade glioma

New drug to target tumor cells and blood vessels

New drug to target tumor cells and blood vessels

Discovery of possible way to block the spread of deadly brain tumors

New imaging analysis method predicts brain tumor survival

Avastin safe and effective at delaying tumor progression

Advances in stem cell research

European Commission and US FDA approve intravenous formulation of temozolomide

Brain tumor treatment may increase number of cancer stem-like cells

Mutations in two genes linked to most common brain cancers

Temozolomide sales reach $1 billion

Innovations in baculovirus–insect cell expression systems

Compound Management and its Crucial Role in Early Pharmaceutical Research

Natural products: the next frontier in drug discovery

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