Gliomas News and Research

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New drug could transform treatment of brain tumors in younger people

A top UVA Health cancer expert is highlighting how a new drug could transform how doctors treat a brain tumor that typically strikes younger people.

25 Aug 2023

New drug candidate nearly doubles survival for patients with aggressive childhood brain tumors

For the first time, researchers have found a potential drug candidate that improved outcomes for patients with a type of childhood brain tumor for which there are no effective treatments.

17 Aug 2023

Henry Ford Health researcher wins grant to study circulating cell-free DNA methylation as a tool for glioma detection

Houtan Noushmehr, Ph.D., a researcher at Henry Ford Health, has been awarded a prestigious R01 grant of nearly $2.9M from the National Institutes of Health (NIH) to support a research project titled, "Circulating cell-free DNA methylation as an accurate tool for detection and clinical follow-up of glioma."

27 Jul 2023

AI tool can rapidly decode brain tumor DNA during surgery

Scientists have designed an AI tool that can rapidly decode a brain tumor's DNA to determine its molecular identity during surgery -; critical information that under the current approach can take a few days and up to a few weeks.

7 Jul 2023

Ancient retrovirus may be responsible for aggressive brain cancers

The median length of survival after diagnosis of glioblastoma is 14 months, but some of these brain tumors are more aggressive and resistant to treatment than others, and a new study from Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine suggests reactivation of an ancient retrovirus may be at least partly to blame.

3 Jul 2023

New technology to capture and release cfDNA on nanowire surfaces from urine

A group led by researchers at Nagoya University in Japan has developed a technology to capture and release cell-free DNA (cfDNA) on nanowire surfaces from urine.

3 Jul 2023

New and significant breakthrough made to detect brain tumors

Folate-based radiopharmaceuticals can be used in positron emission tomography (PET) imaging to detect folate receptors in brain tumors.

15 Jun 2023

Revolution in neuroscience: 2D nanomaterials propel advances in brain repair, treatment, and diagnosis

Review discusses the increasing importance of two-dimensional nanomaterials like graphene in neuroscience, highlighting their potential in nerve repair, creating brain-mimicking synaptic devices, and treating neurological disorders. It also considers the challenges and future prospects of these materials in this complex field.

11 Jun 2023

Study suggests possible new treatment option for people with slow-growing but deadly brain tumor

In an international study co-led by UCLA, scientists have shown that a new targeted therapy drug can extend the amount of time people with a subtype of glioma are on treatment without their cancer worsening.

4 Jun 2023

Researchers create an open-source, reproducible analysis platform for pediatric brain tumors

Researchers from Children's Hospital of Philadelphia, the Alex's Lemonade Stand Foundation Childhood Cancer Data Lab, the Children's Brain Tumor Network, the Pacific Pediatric Neuro-Oncology Consortium, and more than 20 additional institutions have partnered to create a first-of-its-kind open-source, reproducible analysis platform for pediatric brain tumors.

31 May 2023

High-grade gliomas remodel neural circuits: promoting tumor progression and impaired cognition

Researchers investigated whether functional connectivity between glioblastoma and the brain affected neural circuits.

9 May 2023

New approach to CAR T-cell therapy shows promise against small cell lung cancer in preclinical study

A new approach to chimeric antigen receptor T-cell (CAR T) therapy has shown great promise against small cell lung cancer (SCLC) in a preclinical study.

25 Apr 2023

People with a rare form of brain and spinal cord cancer have poor prognosis, research reports

A team of researchers from the Nagoya University Graduate School of Medicine has reported that patients with a rare form of brain and spinal cord cancer, localized isocitrate dehydrogenase wild-type (IDHwt) histologically diffuse astrocytoma, have a poor prognosis similar to the most malignant types of brain and spinal cord tumors.

31 Mar 2023

AI-based diagnostic screening system could streamline the diagnosis and treatment of gliomas

Using artificial intelligence, researchers have discovered how to screen for genetic mutations in cancerous brain tumors in under 90 seconds -; and possibly streamline the diagnosis and treatment of gliomas, a study suggests.

23 Mar 2023

Study reveals the LDLR pathway as a ubiquitous metabolic vulnerability in high grade gliomas

New research has shown that the blood vessels that feed aggressive brain tumors have receptors that could allow a new type of drug-containing nanoparticle to be used to starve the tumors of the energy they use to grow and spread, and also cause other disruptions to their adapted existence, even killing themselves.

7 Mar 2023

Gliomas News and Research

New drug could transform treatment of brain tumors in younger people

New drug candidate nearly doubles survival for patients with aggressive childhood brain tumors

Henry Ford Health researcher wins grant to study circulating cell-free DNA methylation as a tool for glioma detection

AI tool can rapidly decode brain tumor DNA during surgery

Ancient retrovirus may be responsible for aggressive brain cancers

New technology to capture and release cfDNA on nanowire surfaces from urine

New and significant breakthrough made to detect brain tumors

Revolution in neuroscience: 2D nanomaterials propel advances in brain repair, treatment, and diagnosis

Study suggests possible new treatment option for people with slow-growing but deadly brain tumor

Researchers create an open-source, reproducible analysis platform for pediatric brain tumors

High-grade gliomas remodel neural circuits: promoting tumor progression and impaired cognition

New approach to CAR T-cell therapy shows promise against small cell lung cancer in preclinical study

People with a rare form of brain and spinal cord cancer have poor prognosis, research reports

AI-based diagnostic screening system could streamline the diagnosis and treatment of gliomas

Study reveals the LDLR pathway as a ubiquitous metabolic vulnerability in high grade gliomas

Head injuries may contribute to the development of glioma

New cooling strategy could prevent the growth of glioblastoma

Neurosurgeons discover potential markers of glial brain tumors

Pt(IV)-conjugated drug-delivery system shows efficacy in glioblastoma therapy

Novel nanotechnology triggers potent therapeutic anti-tumor immune responses against multiple cancers

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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