Glomerulosclerosis News and Research

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Glomerulosclerosis refers to the scarring of the glomeruli in the kidneys following any type of insult.

Kidney donated two weeks after transplant

For the first time, a kidney that had been donated to a patient in need was removed and implanted into a new patient, the third individual to have the organ, after it failed in the first transplant recipient. Ray Fearing, a 27-year-old Arlington Heights resident received the organ from his sister, Cera, after a long battle with focal segmental glomerulosclerosis (FSGS), a disease in which scar tissue develops on the part of the kidney that filters waste out of the blood, ultimately causing kidney failure.

26 Apr 2012

New research on link between APOL1 gene variants and kidney disease in African Americans

Compared to European Americans, African Americans are four to five times more likely to develop kidney failure. Also, family members of African Americans with kidney failure have an increased risk of developing kidney failure, which suggests that genetics may play a role in this skewed risk between races.

15 Oct 2011

JASN publishes positive results from pirfenidone study in diabetic nephropathy

Researchers at the University of California, San Diego School of Medicine, the National Institutes of Health and the Mayo Clinic have published promising results of a clinical study using an experimental anti-fibrotic and anti-inflammatory drug called pirfenidone to treat patients with diabetic nephropathy. Their study will be published in the April 21 issue of the Journal of the American Society of Nephrology.

22 Apr 2011

INF2 gene mutation is a major cause for focal segmental glomerulosclerosis

Mutations in a gene called INF2 are by far the most common cause of a dominantly inherited condition that leads to kidney failure, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology. The results may help with screening, prevention, and therapy.

21 Jan 2011

UAB researchers pinpoint protein that causes nephrotic syndrome

University of Alabama at Birmingham researchers have pinpointed a protein that compromises the kidney's filtering ability, causing nephrotic syndrome, and demonstrated that a naturally occurring precursor of an acid in the body offers potential for treating some forms of the condition.

13 Dec 2010

Researchers discover genetic explanation for non-diabetic kidney disease in African-Americans

Kidney disease is a growing public health problem, with approximately half a million individuals in the United States requiring dialysis treatments to replace the function of their failed kidneys. The problem is particularly acute among African-Americans, whose rates of kidney disease are four times higher than those of European Americans.

20 Jul 2010

Study identifies a region in human genome that is linked to FSGS

An in-depth study of a family with multiple generations affected by kidney disease has identified a previously unknown location for a gene abnormality causing focal segmental glomerulosclerosis, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology.

9 Jul 2010

Kidneys of healthy adults show signs of chronic injury, says study

Mayo Clinic researchers have found that the kidneys of healthy adults show signs of chronic mild injury that increase with age. This damage is present even though the adults showed no clinical signs of kidney disease.

4 May 2010

Kidneys of healthy adults show signs of chronic mild injury that increase with age: Mayo Clinic

4 May 2010

Discovery suggests how toxin-filtering cells go awry

Researchers from Children's Hospital Boston and Brigham and Women's Hospital have identified an important genetic cause of a devastating kidney disease that is the second leading cause of kidney failure in children, according to The NephCure Foundation.

22 Dec 2009

Anabolic steroids may cause severe kidney dysfunction

Athletes who use anabolic steroids may gain muscle mass and strength, but they can also destroy their kidney function, according to a paper being presented at the American Society of Nephrology's 42nd Annual Meeting and Scientific Exposition in San Diego, CA.

30 Oct 2009

Kidney Care Partners commends CBC for supporting reforms to improve access to quality kidney care

Kidney Care Partners - an alliance of patient advocates, dialysis professionals, care providers and manufacturers working together to improve quality of care for individuals with kidney disease and kidney failure - today applauded the Congressional Black Caucus (CBC) for supporting reforms that will improve patient access and choice in receiving quality kidney care.

13 Oct 2009

NIH, NephCure Foundation and University of Michigan support study of nephrotic syndrome

University of Michigan Health System researchers will lead a $10.25 million effort to study rare kidney diseases that cause kidney failure and the need for dialysis.

23 Sep 2009

Rosiglitazone shows potential for treating focal segmental glomerulosclerosis

The antidiabetes drug rosiglitazone may have the potential to protect kidney function in patients with a condition called focal segmental glomerulosclerosis (FSGS), according to a study appearing in the January 2009 issue of the Clinical Journal of the American Society Nephrology (CJASN).

10 Dec 2008

Low birth weight a risk factor for focal segmental glomerulosclerosis

Individuals who were underweight at birth are at increased risk of developing a condition called secondary focal segmental glomerulosclerosis, according to a study appearing in the January 2009 issue of the Clinical Journal of the American Society Nephrology ( CJASN ).

19 Nov 2008