Glucagon News and Research

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What is the association between obesity and insulin resistance in youth and its production of colon-derived acetate, gut-derived hormone secretion, and adipose tissue lipolysis?

Researchers assessed whether insulin resistance and adiposity in youth were linked to the fermentation of dietary fibers.

11 May 2023

Cardiovascular risk reduction in type 2 diabetes: Study urges better use of life-saving therapies

Researchers explore the efficacy of current approaches to reduce the risk of cardiovascular events in patients with type 2 diabetes.

10 May 2023

Boosting gut health with short-chain fatty acids

Research paper provides an overview of short-chain fatty acids (SCFAs) and their role in regulating gut homeostasis. It also discusses SCFA-producing bacteria and potential therapeutic approaches to boost SCFA levels in the gut to treat related diseases.

9 May 2023

Insights from experts on the neurobiological processes involved in appetite regulation

Researchers summarized the main findings related to the neurobiological regulation of appetite presented at the 23rd Harvard Nutrition Obesity Symposium in June 2022.

8 May 2023

Study evaluates simultaneous effects of exercise and diet-induced weight reduction in patients with type 2 diabetes

Researchers performed a four-armed, 16-week randomized clinical trial on type II diabetes.

3 May 2023

Does the skin microbiome contribute to protection from prolonged solar damage?

Researchers examined how the skin microbiome contributes to protection from solar damage.

19 Apr 2023

Pathophysiology, comorbidities, and interventions related to childhood obesity

Researchers discuss the psychological and physiological impacts of obesity on children.

6 Apr 2023

Experimental anti-obesity drug may control appetite without surgery or nausea

Imagine getting the benefits of gastric bypass surgery without going under the knife -; a new class of compounds could do just that. In lab animals, these potential treatments reduce weight dramatically and lower blood glucose.

29 Mar 2023

The relationship between intestinal microbiome dysbiosis and atherosclerosis

Researchers investigate the impact of intestinal microbiota dysbiosis on atherosclerotic cardiovascular disease incidence.

15 Mar 2023

Long-acting GIPRA inhibits feeding and lowers body weight in mice with diet-induced obesity

The hormone glucose-dependent insulinotropic polypeptide (GIP) is considered obesogenic. In contrast, GIP receptor agonists (GIPRAs) have shown reduced feeding and body weight in an obese mouse model. Therefore, the precise effects exerted by GIP and GIPRAs remain elusive.

14 Mar 2023

Hypothalamic inflammation and obesity, study suggests a pathological mechanism

In a recent review published in the European Journal of Endocrinology, researchers discussed current research on the relationship between human obesity and inflammation of the hypothalamus.

14 Mar 2023

How gut microbiota control feelings of fullness after eating

A recent study discusses recent findings linking satiety to the gut microbiome.

7 Mar 2023

Statin-related residual inflammation predicts cardiovascular events and mortality

A recent Lancet study assessed the importance of low-density lipoprotein cholesterol (LDLC) and high-sensitivity C-reactive protein (CRP) as risk predictors of cardiovascular death, cardiovascular events, and all-cause death among patients subjected to statins.

7 Mar 2023

Coordinated, multifaceted intervention can improve preventive care for diabetes, heart disease

A multifaceted intervention to improve prescribing practices increased the likelihood that patients with Type 2 diabetes and heart disease would be prescribed three classes of guideline-recommended medications by more than fourfold, according to research being presented at the American College of Cardiology's Annual Scientific Session Together With the World Congress of Cardiology.

6 Mar 2023

A journey back to wellness after three kidney transplants and weight gain

Rowena Roque, 46, was having a problem that many people can relate to: doing everything in her power to lose weight and get healthy but never succeeding.

2 Mar 2023

First clinical trial of GABA/GAD focused exclusively on children with recent onset Type 1 diabetes

For the first time, humans with newly diagnosed Type 1 diabetes, or T1D, have received two treatments called GABA and GAD that have shown promise in animal studies and in isolated human pancreas islets. This investigator-initiated clinical trial, published in Nature Communications, focused exclusively on children with recent onset T1D.

22 Feb 2023

Glucagon News and Research

What is the association between obesity and insulin resistance in youth and its production of colon-derived acetate, gut-derived hormone secretion, and adipose tissue lipolysis?

Cardiovascular risk reduction in type 2 diabetes: Study urges better use of life-saving therapies

Boosting gut health with short-chain fatty acids

Insights from experts on the neurobiological processes involved in appetite regulation

Study evaluates simultaneous effects of exercise and diet-induced weight reduction in patients with type 2 diabetes

Does the skin microbiome contribute to protection from prolonged solar damage?

Pathophysiology, comorbidities, and interventions related to childhood obesity

Experimental anti-obesity drug may control appetite without surgery or nausea

The relationship between intestinal microbiome dysbiosis and atherosclerosis

Long-acting GIPRA inhibits feeding and lowers body weight in mice with diet-induced obesity

Hypothalamic inflammation and obesity, study suggests a pathological mechanism

How gut microbiota control feelings of fullness after eating

Statin-related residual inflammation predicts cardiovascular events and mortality

Coordinated, multifaceted intervention can improve preventive care for diabetes, heart disease

A journey back to wellness after three kidney transplants and weight gain

First clinical trial of GABA/GAD focused exclusively on children with recent onset Type 1 diabetes

Are SGLT2 inhibitors the next blockbuster drug?

Study provides a rare view of real-world use of off-label drugs prescribed for Type 1 diabetes

Preventing, diagnosing, and treating cardiovascular disease in women

Gut hormone receptor polyagonists show promise for obesity and diabetes

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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