Glucocorticoid News and Research

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Glucocorticoid is a compound that belongs to the family of compounds called corticosteroids (steroids). Glucocorticoids affect metabolism and have anti-inflammatory and immunosuppressive effects. They may be naturally produced (hormones) or synthetic (drugs).

Adolescence stress exposure impacts rodent brain development and behavior

Adolescence stress exposure in rodents can lead to reduced hippocampal cell proliferation, neuroplasticity, and cognitive impairments, as well as increased depressive-like behaviors. These effects may persist into adulthood but with variable impact.

27 Aug 2023

Study explores the diverse expression patterns of T cell priming markers across cancers

A recent study explored transcriptomics of T-cell priming markers (TPMs) across different cancers.

10 Aug 2023

Are inflammatory bowel disease patients more at risk of colorectal cancer?

Researchers analyzed data from a large cohort of inflammatory bowel disease patients and looked at the risk and frequency of colorectal cancer.

9 Aug 2023

Childhood abuse can induce stress that changes neural networks and functions during growth

Childhood neglect and/or abuse can induce extreme stress that significantly changes neural networks and functions during growth. This can lead to mental illnesses, including depression and schizophrenia, but the exact mechanism and means to control it were yet to be discovered.

4 Aug 2023

Study finds that patients with systemic autoimmune rheumatic diseases had a lower antibody response than healthy controls after Omicron infection

Study investigated if patients with systemic autoimmune rheumatic diseases (SARDs) have a reduced immunological response.

27 Jul 2023

Cervical fibroblasts in cervical insufficiency patients show impaired responses to progesterone

The study described in Scientific Reports highlights an impaired response to the hormone progesterone (P4) in cervical fibroblasts from patients with refractory cervical insufficiency (CI).

26 Jul 2023

Fungal infections: A rare but important cause of chronic sinusitis

A new research perspective was published in Oncoscience (Volume 10) on May 27, 2023, entitled, "Think outside the box – atypical infections in chronic sinusitis."

14 Jul 2023

2023 recipients of the Diversity in Lupus Research Awards announced

The Lupus Research Alliance is pleased to announce the 2023 recipients of the Career Development and Postdoctoral Awards to Promote Diversity in Lupus Research.

12 Jul 2023

Susan G. Komen awards $19.3 million to advance precision medicine and improve breast cancer outcomes

Susan G. Komen, the world's leading breast cancer organization, today announced the awarding of 49 new grants to researchers at 28 leading institutions in the U.S.

28 Jun 2023

Study reveals neural circuits underlying adolescent stress-induced postpartum social behavior

Stress during adolescence can cause postpartum behavioral changes in women and other mammals, including depression and changes in social behavior after the birth of a child.

23 Jun 2023

Research sheds light on how steroids affect cancer Immunotherapy

Immunotherapy is among the newest and most potent weapons against cancer. It prompts the immune system to recognize tumors as intruders in the body and attack. But not all patients respond well to immunotherapy. Why? Scientists aren't always sure.

23 Jun 2023

Mental health profoundly impacts inflammatory responses in the body

Study uncovered mechanisms by which psychological stress affects bowel inflammation.

30 May 2023

People with higher long-term hair glucocorticoid levels more likely to develop heart, circulatory diseases

New research being presented at this year's European Congress on Obesity (ECO) in Dublin, Ireland (17-20 May) suggests that glucocorticoid levels (a class of steroid hormones secreted as a response to stress) present in the hair of individuals may indicate which of them are more likely to suffer from cardiovascular diseases (CVD) in the future.

22 May 2023

Researchers discover how corticosteroids influence inflammatory response during COVID-19 infection

Since the start of the COVID-19 pandemic, a class of corticosteroids called glucocorticoids (GCs) have become established as one of the main treatment options, especially for severe cases, thanks to their anti-inflammatory and immunosuppressant action.

18 May 2023

Case report on Nocardia pseudobrasiliensis and SARS-CoV-2 concomitant infection

In a recent case report published in the U.S. Centers for Disease Control and Prevention’s (CDC) journal Emerging Infectious Diseases, researchers reported a case of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and Nocardia pseudobrasiliensis concomitant infection.

27 Mar 2023

Combined glucocorticoid steroids and statin therapy may be safer for the treatment of preterm birth

Potentially life-saving steroids commonly given to preterm babies also increase the risk of long-term cardiovascular problems, but a new study in rats has found that if given in conjunction with statins, their positive effects remain while the potential negative side-effects are 'weeded out'.

2 Feb 2023

Glucocorticoid News and Research

Adolescence stress exposure impacts rodent brain development and behavior

Study explores the diverse expression patterns of T cell priming markers across cancers

Are inflammatory bowel disease patients more at risk of colorectal cancer?

Childhood abuse can induce stress that changes neural networks and functions during growth

Study finds that patients with systemic autoimmune rheumatic diseases had a lower antibody response than healthy controls after Omicron infection

Cervical fibroblasts in cervical insufficiency patients show impaired responses to progesterone

Fungal infections: A rare but important cause of chronic sinusitis

2023 recipients of the Diversity in Lupus Research Awards announced

Susan G. Komen awards $19.3 million to advance precision medicine and improve breast cancer outcomes

Study reveals neural circuits underlying adolescent stress-induced postpartum social behavior

Research sheds light on how steroids affect cancer Immunotherapy

Mental health profoundly impacts inflammatory responses in the body

People with higher long-term hair glucocorticoid levels more likely to develop heart, circulatory diseases

Researchers discover how corticosteroids influence inflammatory response during COVID-19 infection

Case report on Nocardia pseudobrasiliensis and SARS-CoV-2 concomitant infection

Combined glucocorticoid steroids and statin therapy may be safer for the treatment of preterm birth

Immunological interactions between asthma, obesity, and the microbiota

MIS-C more common and severe than previously thought

Extraordinary plasticity of the glucocorticoid receptor revealed

National Institutes of Health funds a five-year, $11 million initiative

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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