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New drug tricks the body into burning off fat

French scientists have found a drug they say tricks the body into burning off fat - and it even works on a high-fat diet.

5 Nov 2008

New weapon in the fight against obesity and diabetes

A study appearing November 5 in the journal Cell Metabolism demonstrates that a synthetic new chemical entity protects against diet-induced obesity, improves glucose tolerance and insulin sensitivity and enhances exercise endurance by enhancing fat utilization in certain target tissues.

4 Nov 2008

Halozyme Therapeutics starts phase 2 trial of insulin with rHuPH20 in type 1 diabetes

Halozyme Therapeutics, Inc. today announced it has started a Phase 2 study of proprietary recombinant human hyaluronidase enzyme (rHuPH20) co-formulations with Humulin R (regular insulin human injection) and with Humalog (insulin lispro) in Type 1 diabetic patients.

3 Nov 2008

Alternative splicing in genes more prevalent than previously believed

Scientists have long known that it's possible for one gene to produce slightly different forms of the same protein by skipping or including certain sequences from the messenger RNA.

2 Nov 2008

Malaria medication hydroxychloroquine prevents diabetes in arthritis patients

The use of an antimalarial medication may prevent the onset of diabetes in patients with rheumatoid arthritis, new Geisinger research shows.

28 Oct 2008

Scientists discover a catalytic antibody that degrades a known appetite stimulant

The antibody works against the gastric hormone ghrelin (pronounced "grell-in"), which has been linked to weight gain and fat storage through its metabolic actions. These findings point towards a potentially novel treatment for obesity that would interfere directly with the some of the biological mechanisms determining weight.

28 Oct 2008

Life in Canada more deadly for immigrants?

Immigrants who come to Canada seeking a better life may in fact be setting themselves up for possible premature death.

26 Oct 2008

Education and work help beat Alzheimer's

New research has revealed that education and a mentally demanding job protects people from Alzheimer's disease.

22 Oct 2008

Diabetics more likely to lose their vision

Experts in the United States have found that vision loss is more common in people with diabetes than those without the disease.

14 Oct 2008

Visual impairment more common in people with diabetes

Visual impairment appears to be more common in people with diabetes than in those without the disease, according to a report in the October issue of Archives of Ophthalmology.

13 Oct 2008

Obese teenagers face higher metabolic syndrome risk in South America than Europe

Obese teenagers are much more likely to suffer from metabolic syndrome - which can lead to heart disease - if they live in Brazil than Italy, according to a study in the October issue of IJCP, the International Journal of Clinical Practice.

13 Oct 2008

FDA continues review of Takeda's NDA for Alogliptin

Takeda Pharmaceutical Company Limited has announced that Takeda Global Research and Development Center, Inc., a wholly owned United States (U.S.) subsidiary, received notification that the U.S. Food and Drug Administration (FDA) will not be able to complete its review of the alogliptin New Drug Application (NDA) by the Prescription Drug User Fee Act (PDUFA) date of October 27, 2008.

12 Oct 2008