Glucose Metabolism News and Research

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Fatty acid synthase provides new target for treatment of obesity and diabetes

Researchers at Washington University School of Medicine in St. Louis have identified a potential target for treating diabetes and obesity.

3 Aug 2012

Ginger muscles in on diabetes

Ginger, the common spice and ancient Asian remedy, could have the power to help manage the high levels of blood sugar which create complications for long-term diabetic patients, a University of Sydney study reports.

2 Aug 2012

Researchers use computational analysis to identify new Achilles heel for drug-resistant breast cancer

Researchers have used computational analysis to identify a new Achilles heel for the treatment of drug-resistant breast cancer. The results, which are published in Molecular Systems Biology, reveal that the disruption of glucose metabolism is an effective therapeutic strategy for the treatment of tumours that have acquired resistance to front-line cancer drugs such as Lapatinib.

31 Jul 2012

Obesity and heart disease risk in children: an interview with Joana Kist-van Holthe

'What defines obesity in children' is a very important question, primarily because we need to use one definition in order to be able to compare the prevalence of obesity in different countries. It is also important to have a single definition in order to evaluate whether interventions are successful or not.

31 Jul 2012

New blood sugar monitor: An interview with Sherita Hill Golden

Type 1 diabetes is a disorder in which the body makes proteins (antibodies) against the cells in the pancreas that produce insulin, destroying those cells. As a result, individuals are unable to secrete insulin to normalize blood sugar and hyperglycemia results.

20 Jul 2012

Alzheimer’s pathology lies silent for decades

The pathologic process of Alzheimer’s disease begins more than 20 years before clinical symptoms become apparent, say researchers.

18 Jul 2012

How does exercise improve heart function in diabetics?

A detailed study of heart muscle function in mice has uncovered evidence to explain why exercise is beneficial for heart function in type 2 diabetes.

18 Jul 2012

Steroid receptor gene variant impacts metabolic health

A variant in the glucocorticoid receptor gene may be associated with increased body fat and insulin resistance, show study findings.

10 Jul 2012

Steroid receptor gene variant impacts metabolic health

A variant in the glucocorticoid receptor gene may be associated with increased body fat and insulin resistance, show study findings.

10 Jul 2012

New blood sugar monitor works better than conventional methods

Newer technologies designed to help people with type 1 diabetes monitor their blood sugar levels daily work better than traditional methods and require fewer painful needle sticks, new Johns Hopkins research suggests.

10 Jul 2012

MiR-125b downregulated in both aggressive and indolent forms of CLL

Loss of a particular microRNA in chronic lymphocytic leukemia shuts down normal cell metabolism and turns up alternative mechanisms that enable cancer cells to produce the energy and build the molecules they need to proliferate and invade neighboring tissue.

6 Jul 2012

Transcranial direct current stimulation can enhance outcome of swallowing therapy for post-stroke dysphagia

After stroke, patients often suffer from dysphagia, a swallowing disorder that results in greater healthcare costs and higher rates of complications such as dehydration, malnutrition, and pneumonia.

2 Jul 2012

New drug for Type 2 diabetes results in less hypoglycaemia, less weight gain and perhaps less cardiovascular risk for patients

A new drug could offer significant advantages over existing treatments for Type 2 diabetes patients who don’t respond to metformin, the most commonly prescribed initial drug treatment for the disease. The new drug, linagliptin, results in significantly less weight gain than the most common second-line treatments currently used, and may even carry a smaller risk of cardiovascular events such as heart attack and stroke, according to an Article published Online First in The Lancet.

29 Jun 2012

Study investigates how glucose metabolism affects biochemical signals in cancer cells

Compared to normal cells, cancer cells have a prodigious appetite for glucose, the result of a shift in cell metabolism known as aerobic glycolysis or the "Warburg effect." Researchers focusing on this effect as a possible target for cancer therapies have examined how biochemical signals present in cancer cells regulate the altered metabolic state.

27 Jun 2012

Diabetic Neuropathy: An interview with Dr Brian Callaghan

Diabetes is the number 1 cause of neuropathy, which is a very common condition in itself. In fact, up to half of all neuropathy is caused by diabetes, although other people can get the condition as well.

25 Jun 2012

GI Dynamics announces clinical data about EndoBarrier Therapy at ASMBS meeting

GI Dynamics, Inc. announced today that clinical data about EndoBarrier Therapy, a breakthrough treatment for type 2 diabetes and/or obesity, was presented at the 29th Annual Meeting of the American Society for Metabolic & Bariatric Surgery (ASMBS) in San Diego.

23 Jun 2012

Glucose-lowering regulations in people with prediabetes achieves reduction in progression to diabetes in the long term

People with “prediabetes” (a high risk state for overt type 2 diabetes) who experience a period of normal glucose regulation are 56% less likely to develop diabetes 5∙7 years later, according to a new research Article presented at the American Diabetes Association 72nd Scientific Sessions on Saturday 9 June, and published Online First in The Lancet. This is one of four Articles (all presented at the American Diabetes Association 72nd Scientific Sessions) and a Series of three papers that are part of a special Lancet theme issue on diabetes [1].

11 Jun 2012

Blocking Skp2 protein might inhibit glycolysis and treat breast cancer

HER2 and its epidermal growth factor receptor cousins mobilize a specialized protein to activate a major player in cancer development and sugar metabolism, scientists report in the May 25 issue of Cell.

28 May 2012

Omega-3 fatty acids may provide more benefits for elderly people with Alzheimer's

According to a recent study published online in Neurology, Omega-3 fatty acids, like those found in Omega XL fish oil extract containing DHA and EPA from the New Zealand green-lipped mussel, may provide more benefits for elderly people suffering from Alzheimer's.

24 May 2012

Strong link between birth weight and glucose metabolism in old age

Small babies had significantly higher blood glucose and insulin levels and a higher risk of diabetes at the age of 75 and older. The risk of diabetes in old age was five-fold among those born small but who were obese in midlife compared to those with higher birth weight and low body mass index in adulthood.

21 May 2012