Glycation News and Research

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High-heat caramelization can increase risk of heart disease, stroke

From MasterChef to MKR, the world's best chefs have taught us how to barbeque, grill and panfry a steak to perfection. But while the experts may be seeking that extra flavour, new research from the University of South Australia suggests high-heat caramelization could be bad for our health.

4 Sep 2020

Study finds link between high levels of dietary AGEs and breast cancer risk

Hollings Cancer Center researchers at the Medical University of South Carolina and colleagues assessed the connection between dietary advanced glycation end products and breast cancer risk in a study first published online March 2020 in Cancer Prevention Research.

12 Jun 2020

$Innovative technique aims to predict and reduce fractures in diabetics$

Innovative technique aims to predict and reduce fractures in diabetics

People with diabetes face a significantly higher risk of osteoporotic fractures than those without the disease, but the reason for this is not well understood and can't be adequately predicted.

4 Nov 2019

Physiologists, researchers to discuss factors underlying cardiovascular disease at APS conference

International physiologists and researchers studying the kidney, high blood pressure and related medical conditions will convene next week at the American Physiological Society (APS) Aldosterone and ENaC in Health and Disease: The Kidney and Beyond Conference in Estes Park, Colo.

25 Sep 2019

Analysis of lens in the eye can predict patients with type 2 diabetes and prediabetes

New research presented at this year's annual meeting of the European Association for the Study of Diabetes in Barcelona, Spain (16-20 September) shows that specialist analysis of the lens in the eye can predict patients with type 2 diabetes and impaired glucose tolerance (IGT) (also known as prediabetes, a condition that often leads to full blown of type 2 diabetes).

16 Sep 2019

Exercise may reduce artery stiffening associated with heart failure

New research suggests exercise may prevent or lessen artery stiffening associated with heart failure by limiting the buildup of unsafe chemicals around the heart.

30 Jul 2019

Using popular anticonvulsant drug to thwart inflammation

Serious conditions, including sepsis, stem from inflammation in the body, and there is a lack of effective medication for sepsis.

2 Jul 2019

Allergies linked to higher junk food consumption, suggests new study

Many childhood food allergies could be due to eating junk food, according to a new study. Children with food allergies, and children who eat a lot of junk food, have increased body levels of molecules called advanced glycation end-products (AGEs).

10 Jun 2019

Cornell research explains increased metastatic cancer risk in diabetics

As if people living with diabetes didn't have enough health concerns, here's another: increased risk of metastatic cancer. New Cornell University research points to a possible explanation for this health double whammy.

1 May 2019

MUSC researchers link higher levels of AGEs to ER-positive breast cancer risk

Poor diet and lack of exercise are associated with cancer development, but the underlying biology is not well understood. Advanced glycation end products could offer a biological link to help us understand how certain lifestyle behaviors increase cancer risk or lessen the likelihood that an anti-cancer therapy will be effective.

28 Dec 2018

Osteoporosis is not only a women's disease

Osteoporosis, a bone disease that can result in painful fractures - typically in the back, hip or wrist - is often thought of as a woman's disease. But men get it too, just usually later in life than women.

18 Dec 2018

Health impact of highly processed summertime staples

With the 4th of July in the rearview mirror and Labor Day coming down the pike, barbecue season is in full swing.

19 Jul 2018

Autism could be predicted from blood or urine tests soon

Thousands of children are being diagnosed with autism on the basis of tests that are mainly based on the behaviour of the child and his or her responses to the tests and behavioural assessments. In short, there are no blood tests or urine tests that can be used to diagnose autism.

19 Feb 2018

Mount Sinai study uncovers potential link between poor diet and back injuries

In a first-of-its-kind study, Mount Sinai researchers have found a possible link between a poor diet and back injuries, especially in women.

31 Jan 2018

Clinical study investigates lifestyle biomarkers in prostate cancer survivors

Advanced glycation end products, which have been linked to many chronic diseases, including diabetes, cardiovascular disease and cancer, build up in the body from birth due to normal metabolism but are often higher in those eating the high-fat, high-sugar, highly processed foods characteristic of the Western diet.

11 Jan 2018

Russian researchers create new approaches to prevention and treatment of diabetes

A team of scientists from the Ural Federal University and the Institute of Immunology and Physiology modeled type 1 diabetes in an experiment to study recovery processes in the pancreas.

11 Dec 2017

Treatment with endogenous protein can heal scarring in the lungs

The endogenous protein RAGE, which has usually been negatively associated with chronic inflammation and diabetic complications, plays a major role in the repair of DNA damage - and also appears to heal tissue damaged as a result of accelerated cell senescence.

27 Nov 2017

MUSC and SCSU join forces to address health disparities

Marvella Ford missed out on a fundamental part of childhood: having grandparents to spoil and take care of her. They all died before she was born. "That's a tremendous loss that you can never overcome. I grew up not having met or seen pictures of any of my grandparents," she said.

27 Oct 2017

Age-related macular degeneration could be arrested by switching to low-glycemic diet, study finds

A study in mice finds that development of age-related macular degeneration (AMD) could be arrested by switching from a high-glycemic diet (starches as are found in white bread) to a low-glycemic (starches found in whole grains).

16 May 2017

Scientists establish ‘tipping point’ molecular link between blood sugar and Alzheimer's disease

For the first time a "tipping point" molecular link between the blood sugar glucose and Alzheimer's disease has been established by scientists, who have shown that excess glucose damages a vital enzyme involved with inflammation response to the early stages of Alzheimer's.

24 Feb 2017