Gout News and Research

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Gout is a type of arthritis that causes painful inflammation in the joints. Usually it affects one joint which is most commonly the big toe. However, it can affect any joint in the body such as the ankles, knees, wrists, elbows and any joints in the hands or finger.

Symptoms of gout usually develop rapidly and usually start at night. The joint may then start to feel normal again with any pain or discomfort eventually disappearing . However, most people who get gout will have further attacks in the future.

The symptoms of gout are caused by an above normal level of urate in the bloodstream, which builds up and forms crystals, mainly in and around joints and especially in the finger and toe joints. This can lead to intensely pain and inflammation.

There are several factors that can increase the level of blood urate. These include a diet rich in purines (which form urate when broken down) such as red meat, seafood and some other foods; excess alcohol consumption; the use of certain medicines such as diuretics; a family history of gout; kidney disease; and overweight or obesity.

Gout affects about 1% of the population and is more common in men, particularly those aged 30 to 60, and in women who have already experienced the menopause.
Research shows alarming prevalence of overfat pandemic in developed countries

Research shows alarming prevalence of overfat pandemic in developed countries

Titanium dioxide nanoparticles can intensify inflammatory reaction in patients with colitis

Titanium dioxide nanoparticles can intensify inflammatory reaction in patients with colitis

Reintroduction of PATA could improve patient access to life-saving drugs

Reintroduction of PATA could improve patient access to life-saving drugs

Combination treatment found to effective in patients with tophaceous gout

Combination treatment found to effective in patients with tophaceous gout

British Society for Rheumatology releases updated clinical guideline for gout management

British Society for Rheumatology releases updated clinical guideline for gout management

Integrated disease management approach may benefit patients with CKD and gout, study suggests

Integrated disease management approach may benefit patients with CKD and gout, study suggests

Increased uric acid levels in early life may lead to high blood pressure later on

Increased uric acid levels in early life may lead to high blood pressure later on

Mice study shows role of yeast in aggravating IBD symptoms

Mice study shows role of yeast in aggravating IBD symptoms

Research may show new ways to repress inflammation at outset

Research may show new ways to repress inflammation at outset

Researchers discover that existing anti-gout drug can reduce severity of opioid withdrawal symptoms

Researchers discover that existing anti-gout drug can reduce severity of opioid withdrawal symptoms

High-fiber diet may inhibit gout-related inflammation

High-fiber diet may inhibit gout-related inflammation

Saint Louis University geriatrician urges older patients to talk to doctors about too many pills

Saint Louis University geriatrician urges older patients to talk to doctors about too many pills

Duke researchers modify popular drug-delivery technology to evade immune responses

Duke researchers modify popular drug-delivery technology to evade immune responses

Elevated urate levels linked to musculo-skeletal pain

Elevated urate levels linked to musculo-skeletal pain

TUM scientists uncover novel mechanisms of action for skin disease medication

TUM scientists uncover novel mechanisms of action for skin disease medication

DASH diet could be effective, non-pharmacologic approach to prevent gout flares

DASH diet could be effective, non-pharmacologic approach to prevent gout flares

Preclinical data on Selecta’s novel immune tolerance platform published in Nature Nanotechnology

Preclinical data on Selecta’s novel immune tolerance platform published in Nature Nanotechnology

Study finds differences in hospitalization trends for gout and rheumatoid arthritis

Study finds differences in hospitalization trends for gout and rheumatoid arthritis

Drinking tart Montmorency cherry juice can reduce early signs of hypertension

Drinking tart Montmorency cherry juice can reduce early signs of hypertension

High-fructose diet during pregnancy may affect fetal growth

High-fructose diet during pregnancy may affect fetal growth