Gout

Gout is a type of arthritis that causes painful inflammation in the joints. Usually it affects one joint which is most commonly the big toe. However, it can affect any joint in the body such as the ankles, knees, wrists, elbows and any joints in the hands or finger.

Symptoms of gout usually develop rapidly and usually start at night. The joint may then start to feel normal again with any pain or discomfort eventually disappearing . However, most people who get gout will have further attacks in the future.

The symptoms of gout are caused by an above normal level of urate in the bloodstream, which builds up and forms crystals, mainly in and around joints and especially in the finger and toe joints. This can lead to intensely pain and inflammation.

There are several factors that can increase the level of blood urate. These include a diet rich in purines (which form urate when broken down) such as red meat, seafood and some other foods; excess alcohol consumption; the use of certain medicines such as diuretics; a family history of gout; kidney disease; and overweight or obesity.

Gout affects about 1% of the population and is more common in men, particularly those aged 30 to 60, and in women who have already experienced the menopause.

Overview

Feature Articles

Latest Gout News and Research

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Exploring the role of iodine in obesity, diabetes, and other metabolic conditions

Discovering the on-switch for rare genetic inflammatory diseases

Discovering the on-switch for rare genetic inflammatory diseases

Gout not just for Victorians: 1 in 40 Brits have this extremely painful disease

Gout not just for Victorians: 1 in 40 Brits have this extremely painful disease

Study uncovers 23 new genetic markers linked to kidney health on the X-chromosome

Study uncovers 23 new genetic markers linked to kidney health on the X-chromosome

Combining ezetimibe and bempedoic acid effectively lowers cholesterol in statin-intolerant patients

Combining ezetimibe and bempedoic acid effectively lowers cholesterol in statin-intolerant patients

Scientists unveil 3D structure of key immune system component

Scientists unveil 3D structure of key immune system component

Study finds doubled risk of fractures in patients with acute calcium pyrophosphate crystal arthritis

Study finds doubled risk of fractures in patients with acute calcium pyrophosphate crystal arthritis

Gut's role in gout: New study unravels microbiome's influence on uric acid levels

Gut's role in gout: New study unravels microbiome's influence on uric acid levels

Students starting school and college in September are at increased risk of serious illnesses

Students starting school and college in September are at increased risk of serious illnesses

Colchicine does not reduce perioperative AF or MINS in major non-cardiac thoracic surgery

Colchicine does not reduce perioperative AF or MINS in major non-cardiac thoracic surgery

Small molecule inhibitor of the NLRP3 inflammasome for treating autoinflammatory diseases

Small molecule inhibitor of the NLRP3 inflammasome for treating autoinflammatory diseases

UAB researchers secure PCORI funding to compare two pathways of post-fracture patient care

UAB researchers secure PCORI funding to compare two pathways of post-fracture patient care

Added sugar consumption linked to greater risk of kidney stones

Added sugar consumption linked to greater risk of kidney stones

Study sheds light on the susceptibility of Chinese men to 60 diseases related to alcohol consumption

Study sheds light on the susceptibility of Chinese men to 60 diseases related to alcohol consumption

Meta-analysis confirms 17 key metabolites as strong predictors of gout

Meta-analysis confirms 17 key metabolites as strong predictors of gout

Report gives fascinating insight into how Brits spend their time

Report gives fascinating insight into how Brits spend their time

Caffeine found to be most effective for treating birth asphyxia

Caffeine found to be most effective for treating birth asphyxia

DASH diet reduces uric acid levels

DASH diet reduces uric acid levels

Covid deaths plummet in England, but dementia and heart disease remain a concern

Covid deaths plummet in England, but dementia and heart disease remain a concern

Alcohol use raises the risks of 61 diseases in Chinese men

Alcohol use raises the risks of 61 diseases in Chinese men

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