Growth Factor News and Research

RSS

Building a bridge from Alzheimer's disease to diabetes and vice versa

Modern societies face the increasing burden of age-related diseases, in particular Alzheimer's disease (AD) and type 2 diabetes (T2D).

12 May 2009

FDA approves Avastin (bevacizumab) for treatment of glioblastoma multiforme

The U.S. Food and Drug Administration recently approved Avastin (bevacizumab) to treat patients with glioblastoma multiforme (GBM) when this form of brain cancer continues to progress following standard therapy.

7 May 2009

Protein kinase JNK1 identified as treatment target for retinopathy in premature babies

Results of a study in mice by researchers at the University of California, San Diego strongly suggest that the protein kinase JNK1 plays a key role in the development of retinopathy in premature infants.

4 May 2009

New light shed on salt-sensitive hypertension

A high salt intake has been implicated in cardiovascular disease risk for 5000 years. But salt-sensitive hypertension still remains an enigma.

4 May 2009

Mitochondrial peptide Humanin linked to neuronal cell survival and regulation of glucose metabolism

Recent studies have shown that the mitochondrial peptide Humanin (HN) protects against neuronal cell death such as happens in Alzheimer's disease.

22 Apr 2009

Mouse model provides a new tool for investigating Wolf-Hirschhorn syndrome

Wolf-Hirschhorn Syndrome (WHS) is a human disease caused by spontaneous genetic deletions.

22 Apr 2009

New insights into protein p75's role Alzheimer's disease

New research at the Salk Institute for Biological Studies casts the role of a neuronal growth factor receptor - long suspected to facilitate the toxic effects of beta amyloid in Alzheimer's disease - in a new light, suggesting the molecule actually protects the neuron in the periphery from beta amyloid-induced damage.

21 Apr 2009

Human foetal stem cells can effectively be used to treat back leg ischaemic ulcers

Treatment of chronic wounds is a continuing clinical problem and socio-economic burden with diabetic foot ulcers alone costing the NHS £300 million a year.

20 Apr 2009

First noninvasive technique to accurately predict mutations in human brain tumors

Donald O'Rourke, MD, Associate Professor of Neurosurgery at the University of Pennsylvania School of Medicine and colleagues, were able to accurately predict the specific genetic mutation that caused brain cancer in a group of patients studied using magnetic resonance imaging (MRI).

20 Apr 2009

Newly discovered epidermal growth factor receptor active in human pancreatic cancers

Finally some promising news about pancreatic cancer, one of the most fatal cancers, due to the difficulties of early detection and the lack of effective therapies: Johns Hopkins University pathologist Akhilesh Pandey has identified an epidermal growth factor receptor aberrantly active in approximately a third of the 250 human pancreatic cancers studied.

20 Apr 2009

Mammalian alpha-fetoprotein affects the development of rat colons

Mammalian alpha-fetoprotein (AFP) is a single-chain glycoprotein and altered serum AFP levels have been observed concurrent with aberrant growth manifestations in some congenital defects and cancer.

20 Apr 2009

Experimental insulin-like growth factor receptor inhibitor a clear clinical candidate for pancreatic cancer therapy

Researchers at Amgen are testing a fully human monoclonal antibody that inhibits the activity of insulin-like growth factors (IGF-1 and IGF-2) and appears to reduce pancreatic cancer cells in early testing, according to a report in Molecular Cancer Therapeutics, a journal of the American Association for Cancer Research.

14 Apr 2009

Visual impairment will increase as population ages, but treatment can mitigate effects

Health care providers can expect a significant increase in age-related macular degeneration as the baby boom generation reaches retirement age, according to a new study by researchers at RTI International and the Centers for Disease Control and Prevention.

13 Apr 2009

New therapies expected to help reduce future burden of age-related macular degeneration

The prevalence of the eye disease age-related macular degeneration is projected to increase substantially by 2050, but the use of new therapies is expected to help mitigate its effects on vision, according to results of simulation modeling reported in the April issue of Archives of Ophthalmology.

13 Apr 2009

Discovery of mechanism of cell type-specific signaling in tumor development

Mayo Clinic researchers have discovered the mechanisms behind two key checkpoints in cell growth and development - factors that may ultimately allow investigators to benchmark progression of tumor cells or stop them from further development.

8 Apr 2009

Transplantation immunity breakthrough

Australian scientists have made a discovery that may one day remove the need for a lifetime of toxic immunosuppressive drugs after organ transplants.

8 Apr 2009

Growth factor TGF-beta helps maintain health of retinal blood vessels

Scientists at Schepens Eye Research Institute have found that the growth factor known as TGF-beta is essential to the health of blood vessels in the retina and that blocking it can cause retinal dysfunction.

8 Apr 2009

Gene delivery appears safe for regenerating tooth-supporting gum tissue

Scientists at the University of Michigan have developed a method of gene delivery that appears safe for regenerating tooth-supporting gum tissue---a discovery that assuages one of the biggest safety concerns surrounding gene therapy research and tissue engineering.

8 Apr 2009

Breakthrough in transplant medicine

Australian scientists have made a breakthrough in transplantation immunity by finding a way of stopping the immune system from rejecting transplanted organs.

8 Apr 2009

Researchers regenerate axons necessary for voluntary movement

For the first time, researchers have clearly shown regeneration of a critical type of nerve fiber that travels between the brain and the spinal cord and which is required for voluntary movement.

6 Apr 2009

Growth Factor News and Research

Building a bridge from Alzheimer's disease to diabetes and vice versa

FDA approves Avastin (bevacizumab) for treatment of glioblastoma multiforme

Protein kinase JNK1 identified as treatment target for retinopathy in premature babies

New light shed on salt-sensitive hypertension

Mitochondrial peptide Humanin linked to neuronal cell survival and regulation of glucose metabolism

Mouse model provides a new tool for investigating Wolf-Hirschhorn syndrome

New insights into protein p75's role Alzheimer's disease

Human foetal stem cells can effectively be used to treat back leg ischaemic ulcers

First noninvasive technique to accurately predict mutations in human brain tumors

Newly discovered epidermal growth factor receptor active in human pancreatic cancers

Mammalian alpha-fetoprotein affects the development of rat colons

Experimental insulin-like growth factor receptor inhibitor a clear clinical candidate for pancreatic cancer therapy

Visual impairment will increase as population ages, but treatment can mitigate effects

New therapies expected to help reduce future burden of age-related macular degeneration

Discovery of mechanism of cell type-specific signaling in tumor development

Transplantation immunity breakthrough

Growth factor TGF-beta helps maintain health of retinal blood vessels

Gene delivery appears safe for regenerating tooth-supporting gum tissue

Breakthrough in transplant medicine

Researchers regenerate axons necessary for voluntary movement

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

Latest News