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Combined application of therapeutic viruses and nanomaterials to revolutionize cancer therapy

Using oncolytic viruses (OVs) in combination with nanomaterials as a novel approach to cancer treatment.

22 Nov 2023

Falk Trust awards $1.35 million to Case Western Reserve researchers for cancer and diabetic retinopathy treatments

A combined $1.35 million from the Dr. Ralph and Marian Falk Medical Research Trust was awarded to two researchers from the Case Western Reserve University School of Medicine to advance their work on finding more effective treatments-;and better options-;for two debilitating diseases.

17 Nov 2023

New study highlights urgent need for specific biomarkers in vascular cognitive impairment and dementia diagnosis

A review in Nature Reviews Neurology discusses the pathophysiological processes in vascular cognitive impairment and dementia (VCID), emphasizing the need for specific biomarkers to differentiate VCID from Alzheimer's disease and to improve diagnosis and treatment strategies, moving beyond reliance on neuroimaging and patient histories.

15 Nov 2023

Fecal microbiota transplantation boosts survival in metastatic colorectal cancer treatment

A recent study in eClinicalMedicine found that fecal microbiota transplantation, combined with fruquintinib and tislelizumab, significantly improved survival rates in patients with microsatellite stable metastatic colorectal cancer, showing manageable safety and notable increases in progression-free and overall survival.

15 Nov 2023

Pioneering study finds predictive biomarker in lung adenocarcinoma

The potential of the transcriptome of tumor-adjacent normal lung tissue in predicting the prognosis of lung cancer.

13 Nov 2023

Next-generation ovarian cancer therapy: Engineered Vδ2 T cells show promise in preclinical trials

A prospective path for allogeneic cellular immunotherapies.

13 Nov 2023

New insights into migraine etiology: the role of hepatocyte growth factor

The causal links between pro-inflammatory cytokine expression and migraine.

10 Nov 2023

Patients with advanced HER2-positive breast cancer live longer if treated with pyrotinib, trial shows

Patients with HER2-positive breast cancer that has started to spread to other parts of the body survive for longer if they are treated with a new drug called pyrotinib, according to results from the longest follow-up of the PHOEBE randomized clinical trial in China.

8 Nov 2023

Atlas of cancer's hidden rules: Unveiling the transcriptomic and epigenetic secrets across 11 tumors

Researchers have mapped the complex epigenetic and transcriptomic landscape of cancer, revealing key regulatory elements across 11 tumor types that could unlock new insights into cancer progression and metastasis.

5 Nov 2023

Decoding long COVID, pathophysiology, epidemiology, diagnosis, and management

Comprehensive review unravels the complexities of long COVID, spanning pathophysiology to management strategies, and underscores the need for targeted therapies and early diagnosis.

5 Nov 2023

Scientists identify progenitor cells that could revolutionize osteoarthritis treatment

Researchers report that osteoarthritis is caused by the loss of Gremlin 1 (Grem1)-lineage chondrogenic progenitor cells.

3 Nov 2023

Brain peptides activate GH–IGF-1 axis to prevent the progression of MASLD, study reveals

Various factors including obesity, diabetes, etc. are related to the etiology of steatotic liver disease (SLD) including metabolic dysfunction-associated steatotic liver disease (MASLD) etiology and resulted in the complications in various organs.

2 Nov 2023

New treatment breakthrough: Pyrotinib combo demonstrates remarkable efficacy for HER2 positive metastatic breast cancer

The safety and efficacy of treating human epidermal growth factor receptor 2 (HER2)-positive metastatic breast cancer with pyrotinib.

2 Nov 2023

Proof-of-concept study holds promise for safer gene therapy techniques for treating immunodeficiencies

Researchers described an approach to edit the recombination-activating gene 2 (RAG2) locus for therapeutic applications.

1 Nov 2023

Osteoarthritis may be treatable and reversible, new study shows

Current osteoarthritis treatment manages symptoms rather than addressing the underlying disease, but a new University of Adelaide study has shown the condition may be treatable and reversible.

31 Oct 2023

Modular nanoparticles developed for targeted drug delivery and neutralizing biological agents

Engineers at the University of California San Diego have developed modular nanoparticles that can be easily customized to target different biological entities such as tumors, viruses or toxins.

30 Oct 2023

Low-cost anti-inflammatory hydrogel could help treat chronic skin lesions in people with diabetes

Researchers in São Paulo state, Brazil, have developed a low-cost anti-inflammatory hydrogel that in future could help treat chronic skin lesions such as those often seen in people with diabetes.

27 Oct 2023

New ERC-funded research project aims to develop targeted treatments for chronic wounds and cancer

the Freiburg University Medical Center and member of the Medical Faculty at the University of Freiburg, has received a European Research Council (ERC) Starting Grant from the European Commission.

27 Oct 2023

New treatment combination shows promise for metastatic colorectal cancer patients with rare genetic mutation

An international Phase 3 clinical trial found that metastatic colorectal cancer patients with a rare genetic tumor mutation called KRAS G12C experienced superior progression-free survival rates compared to standard of care when offered a combination treatment of KRAS inhibitor sotorasib and monoclonal antibody panitumumab.

27 Oct 2023

Researchers identify mechanism through which dietary omega 3 supplements alleviate liver condition

A study spearheaded by Oregon State University has shown why certain polyunsaturated fatty acids work to combat a dangerous liver condition, opening a new avenue of drug research for a disease that currently has no FDA-approved medications.

25 Oct 2023

Growth Factor News and Research

Combined application of therapeutic viruses and nanomaterials to revolutionize cancer therapy

Falk Trust awards $1.35 million to Case Western Reserve researchers for cancer and diabetic retinopathy treatments

New study highlights urgent need for specific biomarkers in vascular cognitive impairment and dementia diagnosis

Fecal microbiota transplantation boosts survival in metastatic colorectal cancer treatment

Pioneering study finds predictive biomarker in lung adenocarcinoma

Next-generation ovarian cancer therapy: Engineered Vδ2 T cells show promise in preclinical trials

New insights into migraine etiology: the role of hepatocyte growth factor

Patients with advanced HER2-positive breast cancer live longer if treated with pyrotinib, trial shows

Atlas of cancer's hidden rules: Unveiling the transcriptomic and epigenetic secrets across 11 tumors

Decoding long COVID, pathophysiology, epidemiology, diagnosis, and management

Scientists identify progenitor cells that could revolutionize osteoarthritis treatment

Brain peptides activate GH–IGF-1 axis to prevent the progression of MASLD, study reveals

New treatment breakthrough: Pyrotinib combo demonstrates remarkable efficacy for HER2 positive metastatic breast cancer

Proof-of-concept study holds promise for safer gene therapy techniques for treating immunodeficiencies

Osteoarthritis may be treatable and reversible, new study shows

Modular nanoparticles developed for targeted drug delivery and neutralizing biological agents

Low-cost anti-inflammatory hydrogel could help treat chronic skin lesions in people with diabetes

New ERC-funded research project aims to develop targeted treatments for chronic wounds and cancer

New treatment combination shows promise for metastatic colorectal cancer patients with rare genetic mutation

Researchers identify mechanism through which dietary omega 3 supplements alleviate liver condition

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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