H3N2 News and Research

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Influenza A virus subtype H3N2 (also H3N2) is a subtype of viruses that cause influenza (flu). H3N2 viruses can infect birds and mammals. In birds, humans, and pigs, the virus has mutated into many strains. H3N2 is increasingly abundant in seasonal influenza, which kills an estimated 36,000 people in the United States each year.

Seasonal influenza triggers significant school closures, especially in southern states, study finds

Study examined closures of United States (US) schools due to 11 influenza seasons between 2011 and 2022.

18 Apr 2024

Newly identified antibodies target a hard-to-spot region of the influenza virus

Researchers at the National Institutes of Health have identified antibodies targeting a hard-to-spot region of the influenza virus, shedding light on the relatively unexplored "dark side" of the neuraminidase (NA) protein head.

1 Mar 2024

Researchers develop promising recombinant flu vaccine using nanoliposome technology

Recombinant protein vaccines, like the Novavax vaccine used to fight COVID-19, offer several advantages over conventional vaccines.

24 Feb 2024

Vaccines safe for pregnant women with HIV but show reduced immune response

A meta-analysis in eClinicalMedicine finds vaccines are safe for pregnant women living with HIV, showing reduced immunogenicity compared to those without HIV but no increase in adverse events, highlighting the need for their inclusion in vaccine trials.

9 Feb 2024

Curcumin spray shows promise in fighting SARS-CoV-2 and flu viruses

A study in the Virology Journal reveals a curcumin-containing oro-nasal film spray with potential antiviral activity against SARS-CoV-2 and influenza viruses, boosting mucosal immunity without cytotoxic effects.

24 Jan 2024

Previously unrecognized class of antibodies can broadly neutralize multiple virus strains

Researchers have identified a previously unrecognized class of antibodies-;immune system proteins that protect against disease-;that appear capable of neutralizing multiple forms of flu virus.

21 Dec 2023

Immunoregulatory nanomedicines for the prevention and treatment of respiratory diseases

Study explores immunoregulatory nanomedicines for respiratory infections, highlighting their potential in enhancing treatment outcomes and vaccine efficacy.

7 Dec 2023

New quantitative analysis of how flu viruses evolved may help predict future strains

Simon Fraser University researchers studying the evolutionary history of flu viruses have found that a new quantitative analysis of how they evolved may help predict future strains.

7 Nov 2023

New insights into why obesity puts individuals at risk for severe influenza

The mechanisms underpinning severe cases of influenza among the obese population.

23 Oct 2023

New mRNA flu vaccine shows promise: Faster to produce, highly effective in mice

The study evaluates the efficacy of a new quadrivalent mRNA influenza vaccine, finding it to be highly immunogenic and protective in a mouse model. Compared to traditional vaccines, the mRNA-based option offers advantages like reduced production time and elimination of the risk of growth-promoting mutations.

15 Oct 2023

Mutational changes in Avian flu virus could increase risk of transmission to humans

A new study from researchers in China and Nottingham has discovered that a subtype of avian flu virus, endemic in poultry farms in China, is undergoing mutational changes, which could increase the risk of the disease being passed on to humans.

5 Sep 2023

Comparative mortality rates of SARS-CoV-2 and influenza in France before and after the COVID-19 pandemic

Researchers investigate the contribution of SARS-CoV-2 and influenza to hospitalizations and mortality to inform future vaccination and treatment policies.

30 Aug 2023

Preventing the next pandemic: swine influenza genomic surveillance essential, study shows

Researchers explored the evolutionary dynamics of swine influenza A virus (swIAV) populations in Asia's southern and eastern regions.

10 Aug 2023

Advances in influenza research

This interview with Dr. Mohammad S Safiarian, Associate Product Manager at Sino Biological, discusses the advances in influenza research and how effective vaccines are developed.

From Sino Biological Inc. 30 Jun 2023

Interim results of the effectiveness of 2022-2023 influenza vaccine from six studies conducted in Europe

Researchers provided interim results on 2022-2023 influenza vaccine effectiveness (VE) estimates.

30 May 2023

The adaptive immunity of human endemic viruses

Researchers studied the evolution of the ability of viruses to evade the neutralizing antibodies.

24 May 2023

Phase 1 trial of experimental universal influenza vaccine begins enrolling volunteers

A clinical trial of an experimental universal influenza vaccine developed by researchers at the National Institute of Allergy and Infectious Diseases' (NIAID) Vaccine Research Center (VRC), part of the National Institutes of Health, has begun enrolling volunteers at Duke University in Durham, North Carolina.

15 May 2023

Study suggests the zoonotic-like avian H3N8 virus has limited efficiency for human-to-human transmission and is unlikely to cause severe disease in humans

Researchers demonstrated that the novel and avian hemagglutinin 3 neuraminidase 8 (H3N8) virus showed limited replication in explant cultures of lung and bronchial tissue.

27 Apr 2023

Evolution of H3 avian influenza virus in China: Implications for pandemic preparedness

This paper analyzes the evolution of the H3 subtype of avian influenza virus in China from 2009 to 2022, including its spatial and temporal distribution and genetic changes. The findings have implications for pandemic preparedness.

18 Apr 2023

Could mink serve as an immediate host for Influenza A transmission?

A recent study discussed influenza A virus infections in minks, emphasizing their contribution/role as an intermediate host.

3 Apr 2023