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Influence of poverty upon health in PLoS Medicine

Everything published by PLoS Medicine is Open Access: freely available for anyone to read, download, redistribute and otherwise use, as long as the authorship is properly attributed.

23 Oct 2007

Genetic influence on HIV/AIDS progression

Viral load - the amount of virus in the blood of an HIV-infected person - has long been viewed as the chief indicator of how quickly someone infected with HIV infection progresses to AIDS.

22 Oct 2007

Critical need for earlier diagnosis and referral of HIV-infected children in Africa

Care provided by nurses and other clinicians in primary health care settings in sub-Saharan Africa can result in good outcomes for children with HIV infection.

22 Oct 2007

HIV is spread most by people with medium levels of HIV in blood

People with medium levels of HIV in their blood are likely to contribute most to the spread of the virus, according to new research published in the journal Proceedings of the National Academy of Sciences.

22 Oct 2007

High-risk individuals less likely to follow through on HIV testing plans

One-fourth of individuals at high risk for contracting HIV report planning to be tested for the virus in the next year, but fewer appear to follow through on that intention than individuals who are at lower risk, according to a report in the October 22 issue of Archives of Internal Medicine.

22 Oct 2007

Good outcomes possible for HIV-infected children in Africa enrolled in pediatric treatment programs

Care provided by nurses and other clinicians in primary health care settings in sub-Saharan Africa can result in good outcomes for children with HIV infection.

22 Oct 2007

Free medications ensure anti-HIV drugs are taken in Africa

HIV-infected patients in the African country of Tanzania were more likely to stop taking their medications and to fail treatment if they had to pay for the drugs themselves.

22 Oct 2007

$6.8 million grant to help UTEP tackle Hispanic health disparities

The Hispanic Health Disparities Research Center at the University of Texas at El Paso has received a $6.8 million grant from the National Institutes of Health that will significantly advance the center's research in helping eliminate racial and ethnic health inequalities across the nation.

22 Oct 2007

Fight against HIV needs local scientists

Scientists from developing countries are vitally important in the fight against HIV and they must be given the proper resources to conduct their work, according to a new commentary published today in the journal Nature Immunology.

22 Oct 2007

GenVec receives extra funding for adenovector-based HIV vaccines program

GenVec, Inc. has announced that the Vaccine Research Center (VRC) of the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), has executed its sixth option period (year seven) under its multi-year collaboration with GenVec to develop and manufacture novel adenovector-based HIV vaccines.

22 Oct 2007

T-cell exhaustion

A new study of immune cells battling a chronic viral infection shows that the cells, called T cells, become exhausted by the fight in specific ways, undergoing profound changes that make them progressively less effective over time.

19 Oct 2007

New model helps explain rules governing the transmission of microbes

Many of the most successful microbes are those that inhabit but do not kill their host. Cheaters lose. Tuberculosis settles into the lungs. Helicobacter pylori, the microbe causing ulcers, burrows into the stomach where it thrives on acids. And Salmonella typhi takes up residence in the gallbladder. All of these organisms can persist in our bodies for decades. What explains their success?

18 Oct 2007

HIV linked to increased risk of end-stage renal disease in African-Americans

For African Americans infected with HIV, the risk of end-stage renal disease (ESRD) is six times higher than for whites with HIV - and similar to the ESRD risk associated with diabetes, reports a study in the November Journal of the American Society of Nephrology.

18 Oct 2007

Scientists discover how HIV evolves

University of Florida scientists have discovered how HIV evolves over the course of a person's lifetime into a more deadly form that heralds the onset of full-blown AIDS.

17 Oct 2007

Existing drugs may be useful in treating brain tumors

Scientists have shown how developing brain tumors can turn an encounter with a signaling molecule from a fatal experience for the tumor cells into a cue for their own growth and multiplication.

17 Oct 2007

Home-based HIV voluntary counseling and testing in developing countries

A review of existing research suggests that people in two African countries prefer taking HIV tests at home, with the assistance of counselors, instead of at a clinic.

17 Oct 2007

One-third of patients receiving HIV medication in Africa don't continue treatment

More than one-third of patients receiving HIV medication in Africa die or discontinue their treatment within two years, according to a study published in PLoS Medicine.

17 Oct 2007

FDA approves raltegravir new HIV drug

The U.S. Food and Drug Administration (FDA) has approved raltegravir tablets for treatment of Human Immunodeficiency Virus (HIV)-1 infection in combination with other antiretroviral agents in treatment-experienced adult patients who have evidence of viral replication and HIV-1 strains resistant to multiple antiretroviral agents.

17 Oct 2007

AHF challenges Merck over Isentress AIDS drug pricing

AIDS Healthcare Foundation (AHF) has criticized Merck and Co. Pharmaceuticals, for the announced price for its key new HIV/AIDS drug, Isentress (raltegravir), an integrase inhibitor approved by the Food and Drug Administration (FDA) Friday, and priced by the company at nearly $9,900 per patient yearly.

17 Oct 2007

Low prevalence of Helicobacter pylori in HIV-positive patients

Helicobacter pylori has been extensively studied and proven to be the main cause of chronic gastritis and peptic ulcer in the HIV-negative population.

17 Oct 2007