Head and Neck Cancer News and Research

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Head and Neck Cancer is cancer that arises in the head or neck region (in the nasal cavity, sinuses, lips, mouth, salivary glands, throat, or larynx [voice box]).

Persistent tumor mutation burden linked with therapeutic response to immunotherapy

Cancer experts have tried, sometimes unsuccessfully, to use the total number of mutations in a tumor, called the tumor mutation burden (TMB), to predict a patient's response to immunotherapy.

26 Jan 2023

Novel T cell receptor therapy shows early promise for treating solid tumors

Afamitresgene autoleucel (afami-cel; formerly ADP-A2M4), an adoptive T cell receptor (TCR) therapy targeting the MAGE-A4 cancer antigen, achieved clinically significant results for patients with multiple solid tumor types in a Phase I clinical trial led by researchers at The University of Texas MD Anderson Cancer Center.

9 Jan 2023

Brief tele-cognitive behavioral therapy for head and neck cancer survivors with body-image distress shows promising results

Talking, smiling, eating together – these are all social activities that are inherent to the human experience. But for some head and neck cancer survivors, they are dreaded tasks.

6 Jan 2023

Research findings could bolster the effectiveness of immune-checkpoint therapy

Immune checkpoint inhibitors such as Keytruda and Opdivo work by unleashing the immune system's T cells to attack tumor cells.

16 Nov 2022

New discovery reveals which patients will survive longer after receiving immunotherapy

Patients with head and neck cancer who have more genetic material on chromosome 9 in their cancer cells survive three times longer after receiving immunotherapy than those with less genetic material there, a new study finds.

14 Nov 2022

New discovery may change the textbook model of GPCR-mediated signaling

Researchers at University of California San Diego have identified a new signaling process involving G protein-coupled receptors (GPCRs), a cellular target already exploited by hundreds of diverse drugs.

27 Oct 2022

Dangers of recreational/medical cannabis use

Researchers describe the wide range of neurological effects associated with cannabis use.

26 Oct 2022

Researchers focus on the identification of markers to improve head and neck cancer risk assessment

Malignant tumors in the head and neck region are very heterogeneous and therefore difficult to treat. In addition, the lack of prognostic markers is a significant impediment to personalized treatment.

25 Oct 2022

Study reveals how a cell signaling molecule can help oral cancer cells acquire high motility

The process of metastasis is when cancer cells gain motility and spread to other sites of the body. Because this is one of the main causes of cancer-related deaths, researchers have aimed to develop therapeutic strategies that can block metastasis.

18 Oct 2022

Cleveland Clinic’s ROBIN center may pave way for more effective radiation, immunotherapy treatments

Cleveland Clinic received a $7.9 million five-year grant from the National Cancer Institute at the National Institutes of Health to form one of three national centers as part of the newly established Radiation Oncology-Biology Integration Network (ROBIN).

22 Sep 2022

Updating alcohol container warning labels could help consumers to make more informed decisions

You know drinking alcohol isn't the best thing for your health, but just how bad is it? After all, in the United States, two thirds of adults report some degree of alcohol use.

8 Sep 2022

Administering immunotherapy drug before surgery for oral cavity cancer did not increase complications

A University of Cincinnati study found administering an immunotherapy drug before surgery for oral cavity cancer did not lead to increased rates of complications during and after surgery.

7 Sep 2022

Terminally exhausted T cells may remain competent for transcription, researchers say

During a battle with cancer, T cells can become exhausted and are no longer able to function properly. The early phase of exhaustion can sometimes be reversed with immunotherapy drugs, but once T cells become too exhausted, it had been thought that this state was irreversible. However, new insights from University of Pittsburgh and UPMC researchers suggest that even the most fatigued T cells can be revived.

8 Aug 2022

Head and Neck Cancer News and Research

Persistent tumor mutation burden linked with therapeutic response to immunotherapy

Novel T cell receptor therapy shows early promise for treating solid tumors

Brief tele-cognitive behavioral therapy for head and neck cancer survivors with body-image distress shows promising results

Research findings could bolster the effectiveness of immune-checkpoint therapy

New discovery reveals which patients will survive longer after receiving immunotherapy

New discovery may change the textbook model of GPCR-mediated signaling

Dangers of recreational/medical cannabis use

Researchers focus on the identification of markers to improve head and neck cancer risk assessment

Study reveals how a cell signaling molecule can help oral cancer cells acquire high motility

Cleveland Clinic’s ROBIN center may pave way for more effective radiation, immunotherapy treatments

Updating alcohol container warning labels could help consumers to make more informed decisions

Administering immunotherapy drug before surgery for oral cavity cancer did not increase complications

Terminally exhausted T cells may remain competent for transcription, researchers say

Locusts can differentiate between cancer cells and healthy cells, research shows

Hearing issues often occur among adult cancer survivors, study reports

Study illustrates how the use of whole exome sequencing can better predict treatment response

MIT chemists discover how changes in a shape-shifting receptor trigger cell growth

Study offers a new and unique treatment for AIDS

Counting metastatic lymph nodes is better for determining prognoses of solid tumors

Research suggests some solutions to combat cancer surgery-induced climate change

Innovations in baculovirus–insect cell expression systems

Compound Management and its Crucial Role in Early Pharmaceutical Research

Natural products: the next frontier in drug discovery

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