Heart Attack (Myocardial Infarction) News and Research

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A Heart Attack (Myocardial Infarction) occurs when blood flow to a section of heart muscle becomes blocked. If the flow of blood isn’t restored quickly, the section of heart muscle becomes damaged from lack of oxygen and begins to die.

Heart attack is a leading killer of both men and women in the United States. But fortunately, today there are excellent treatments for heart attack that can save lives and prevent disabilities. Treatment is most effective when started within 1 hour of the beginning of symptoms. Heart attacks occur most often as a result of a condition called coronary artery disease (CAD). In CAD, a fatty material called plaque (plak) builds up over many years on the inside walls of the coronary arteries (the arteries that supply blood and oxygen to your heart). Eventually, an area of plaque can rupture, causing a blood clot to form on the surface of the plaque. If the clot becomes large enough, it can mostly or completely block the flow of oxygen-rich blood to the part of the heart muscle fed by the artery.

Death rates after surgery: an interview with Dr Rupert Pearse

There are very few published estimates describing the number of deaths following surgery at a national level and none at an international level.

1 Oct 2012

Resuscitation after cardiac arrest: an interview with Zach Goldberger

Cardiac arrest is an important clinical challenge. The event is unexpected and surprising; the patients are challenging, and the outcomes are poor.

13 Sep 2012

Converting blood cells to a stem cell state: an interview with Elias Zambidis, M.D., Ph.D.

The primitive stem cell state we created is called an “induced pluripotent stem cell” (iPSC). iPSC are a new, unique, and artificially-created type of stem cell that were first described in 2006 by a Japanese scientist named Shinya Yamanaka.

4 Sep 2012

Statins: cardiovascular benefits outweigh diabetes risk

The benefits of taking statins to reduce the risk of cardiovascular disease outweigh the increased risk of developing diabetes experienced by some patients who take these cholesterol-lowering drugs, according to an Article published Online First in The Lancet.

10 Aug 2012

Head trauma in older adults over a weekend more deadly than during the week

A Johns Hopkins review of more than 38,000 patient records finds that older adults who sustain substantial head trauma over a weekend are significantly more likely to die from their injuries than those similarly hurt and hospitalized Monday through Friday, even if their injuries are less severe and they have fewer other illnesses than their weekday counterparts.

6 Aug 2012

Heart attack and stroke risk increased with shift work

Shift work is associated with an increased risk of major vascular problems, such as heart attacks and strokes, concludes a study published on bmj.com today.

27 Jul 2012

Heart-protective protein finally found

It is a cellular component so scarce, some scientists even doubted its existence, and many others gave up searching for its molecular structure. Now a team led by researchers at Johns Hopkins has defined the protein structural composition of mitoKATP, a potassium channel in the mitochondria of the heart and other organs that is known to protect against tissue damage due to a heart attack or stroke.

18 Jul 2012

Cells close to death from toxin exposure can survive when toxins are removed

The vast majority of cells that appear to be on a one-way track to death after exposure to toxins can bounce back completely after those toxins are removed, Johns Hopkins scientists report in a new study. The finding, published in the June 15 issue of Molecular Biology of the Cell, is not only a testament to the indomitable cellular spirit, but could also offer some practical insight on how to save dying tissues after heart attacks or strokes as well as prevent cancer in cells transiently exposed to toxins.

3 Jul 2012

New drug for Type 2 diabetes results in less hypoglycaemia, less weight gain and perhaps less cardiovascular risk for patients

A new drug could offer significant advantages over existing treatments for Type 2 diabetes patients who don’t respond to metformin, the most commonly prescribed initial drug treatment for the disease. The new drug, linagliptin, results in significantly less weight gain than the most common second-line treatments currently used, and may even carry a smaller risk of cardiovascular events such as heart attack and stroke, according to an Article published Online First in The Lancet.

29 Jun 2012

Broken heart syndrome may protect the heart from adrenaline overload

A condition that temporarily causes heart failure in people who experience severe stress might actually protect the heart from very high levels of adrenaline, according to a new study published in the journal Circulation. The research provides the first physiological explanation for Takotsubo cardiomyopathy, also called "broken heart syndrome" because it affects people who suffer severe emotional stress after bereavement, and suggests guidance for treatment.

27 Jun 2012

Diabetic Neuropathy: An interview with Dr Brian Callaghan

Diabetes is the number 1 cause of neuropathy, which is a very common condition in itself. In fact, up to half of all neuropathy is caused by diabetes, although other people can get the condition as well.

25 Jun 2012

Coronary risk for chronic kidney disease patients could be as high as for those who have had a heart attack

Patients suffering from chronic kidney disease could be at as high a risk of coronary heart disease as patients who have previously had a heart attack, according to an Article published Online First in the Lancet.

19 Jun 2012

Heart problems in high risk people could be prevented by dark chocolate

Daily consumption of dark chocolate can reduce cardiovascular events, such as heart attacks and strokes, in people with metabolic syndrome (a cluster of factors that increases the risk of developing heart disease and diabetes), finds a study published on bmj.com today.

1 Jun 2012

Major new research facility opens at Imperial College London

A major new research facility at Imperial College London designed to expand and accelerate the translation of scientific discoveries into new ways of preventing, diagnosing and treating diseases was officially opened by George Osborne MP, Chancellor of the Exchequer, today.

28 May 2012

Calcium supplements may increase the risk of heart attack

Calcium supplements might increase the risk of having a heart attack, and should be “taken with caution,” concludes research published in the online issue of the journal Heart.

24 May 2012

Alteplase can benefit stroke patients aged over 80 years according to new studies

The Lancet today publishes two papers Online First about the use of alteplase in stroke, timed to coincide with their presentation at the European Stroke Conference in Lisbon, Portugal.

23 May 2012

Salt intake: why is it bad for you?

Many of us are aware that we shouldn’t eat too much salt. To be precise, adults should avoid eating over 6g (or around about a teaspoon of salt) a day.

21 May 2012

The truth about chocolate: does it really contain flavonoids?

There have been many news stories over the years about chocolate and whether it is good or bad for you. The stories often comment on a chemical constituent of chocolate: flavonoids. But what are flavonoids? Does chocolate even contain them? And why should we care if it does?

18 May 2012

Plans to tackle growing waistlines and the obesity epidemic from the Institute of Medicine

According to the Institute of Medicine (IOM), obesity in America is a crisis that threatens national security and it demands urgent action.

9 May 2012

Novel liquid drug used successfully in a heart attack patient

They did the first procedure of its kind by injecting the dissolvable liquid device into a patient - a Victorian grandmother. The device flows to the damaged heart muscle and helps it repair. The liquid is derived from seaweed and was injected into Pauline Fulton's heart, a fortnight ago, two days after she suffered a major heart attack.

29 Apr 2012