Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

Exercise is safe, improves quality of life in patients With chronic heart failure

Behavior treatment works as well as drugs for children with ADHD and bypasses the risk of medication's side effects, a meta-analysis of 174 studies on ADHD treatment conducted at the University at Buffalo, has shown.

7 Apr 2009

Researchers find an increased rate of unintentional injection of epinephrine from auto-injectors for anaphylaxis

Researchers find an increased rate of unintentional injection of epinephrine from auto-injectors for anaphylaxis (severe allergic reactions) and urge people who may need to administer the life-saving drug to themselves or others in an allergic emergency to receive regular coaching in its proper use.

6 Apr 2009

Anemia treatment improves heart structure and quality of life in kidney disease patients

In chronic kidney disease patients, different levels of anemia treatment have a beneficial effect on the heart and improve quality of life, according to a pair of studies appearing in the April 2009 issue of the Clinical Journal of the American Society Nephrology (CJASN).

1 Apr 2009

One of five hospitalized Medicare patients readmitted to hospital within 30 days

One of five Medicare beneficiaries discharged from the hospital is readmitted within 30 days, and half of non-surgical patients are readmitted to the hospital without having seen an outpatient doctor in follow-up, according to a Commonwealth Fund-supported study in today's New England Journal of Medicine.

1 Apr 2009

Novel assays provide new insight into why patients are in heart failure

A failing heart makes a lot of a hormone needed to eliminate the excess salt and water bloating the body but not enough of the enzyme needed to activate it, researchers say.

1 Apr 2009

New model helps predict risk of new onset heart failure in the elderly

Researchers at Emory University School of Medicine created the Health ABC Heart Failure Model for predicting risk of new onset heart failure in the elderly.

30 Mar 2009

Post heart attack, bone marrow stem cells increase blood flow within heart

Patients treated with their own bone marrow stem cells after a heart attack experienced increased circulation within the heart, a study by Emory University School of Medicine physicians has found.

30 Mar 2009

Corthera's Relaxin in acute heart failure shows promising results

Corthera Inc. has announced that results from Pre-RELAX-AHF, the Phase II portion of a Phase II/III multicenter, randomized, double-blind, placebo-controlled international study, demonstrated promising efficacy and safety for relaxin, the company's investigational drug for treatment of acute heart failure (AHF).

30 Mar 2009

Nile Therapeutics update on phase II CD-NP trial for acute heart failure

Nile Therapeutics, Inc. has announced that, in the course of reviewing the Investigational New Drug (IND) application materials that Nile submitted to the U.S. Food and Drug Administration (FDA) to support the initiation of the Company's Phase IIb clinical trial with CD-NP for the treatment of acute heart failure, the FDA has placed CD-NP on clinical hold.

30 Mar 2009

New Lantheus study finds significant survival benefit for critically ill patients undergoing contrast-enhanced echocardiography

Lantheus Medical Imaging, Inc has announced new data regarding the use of DEFINITY Vial For (Perflutren Lipid Microsphere) Injectable Suspension.

29 Mar 2009

Improved predictive value of biomarkers in HF makes earlier diagnosis and better management possible

With an ever ageing population and more people surviving a heart attack, heart failure is now the world's most prevalent chronic cardiovascular disease.

29 Mar 2009

Improved predictive value of biomarkers in heart failure now makes earlier diagnosis and better management possible

With an ever ageing population and more people surviving a heart attack, heart failure is now the world's most prevalent chronic cardiovascular disease.

29 Mar 2009

ARCA biopharma presents data from phase 3 BEST trial of Gencaro

ARCA biopharma, Inc. has announced that data from the pivotal Phase 3 BEST trial of Gencaro (bucindolol hydrochloride) in patients with advanced chronic heart failure (CHF) was presented at the American College of Cardiology 58 th Annual Scientific Session being held March 29-31, 2009 in Orlando, Florida.

29 Mar 2009

A comparative analysis of four beta blocker trials

ARCA biopharma, Inc. has announced that a comparative analysis of primary endpoint data from four beta blocker trials was presented at the American College of Cardiology 58th Annual Scientific Session being held March 29-31, 2009.

29 Mar 2009

Updated heart failure guidelines focus on key research findings, clinical advances

Updated guidelines on the diagnosis and management of heart failure will help physicians incorporate the latest research findings into the treatment of patients with this complex and disabling disease.

29 Mar 2009

Recently identified genetic heart disorder often deadly for young patients

A study that included young patients with a recently recognized rare type of cardiomyopathy (a disorder of the heart muscle) linked to a genetic mutation finds that progression of this disease may be rapid and often results in early death, according to a study in the March 25 issue of JAMA.

24 Mar 2009

Gilead commences phase II trial of Cicletanine for pulmonary arterial hypertension

Gilead Sciences, Inc. has announced that it has begun enrolling patients in a Phase II clinical trial of cicletanine hydrochloride (cicletanine), an oral agent in development for the treatment of pulmonary arterial hypertension (PAH).

24 Mar 2009

Gleevec reduces risk of cancer returning in patients with life-threatening gastrointestinal stromal tumors

Data published online and in an upcoming print issue of The Lancet show that Gleevec (imatinib mesylate) tablets, when taken after surgery, substantially reduces the rate of recurrence of Kit-positive gastrointestinal stromal tumors (GIST) compared with placebo.

20 Mar 2009

Set of criteria help identify candidates for combined heart and kidney transplants

Researchers have identified a set of criteria that, when combined with a measure of kidney function, could help identify patients who are likely to receive a survival benefit from a combined heart and kidney transplant, according to a report in the March issue of Archives of Surgery.

16 Mar 2009

New target for heart failure therapy identified

A novel signaling pathway plays a significant role in the production of aldosterone, a hormone that promotes heart failure after a myocardial infarction, according to a study conducted by Thomas Jefferson University researchers.

16 Mar 2009

Heart Failure News and Research

Further Reading

Exercise is safe, improves quality of life in patients With chronic heart failure

Researchers find an increased rate of unintentional injection of epinephrine from auto-injectors for anaphylaxis

Anemia treatment improves heart structure and quality of life in kidney disease patients

One of five hospitalized Medicare patients readmitted to hospital within 30 days

Novel assays provide new insight into why patients are in heart failure

New model helps predict risk of new onset heart failure in the elderly

Post heart attack, bone marrow stem cells increase blood flow within heart

Corthera's Relaxin in acute heart failure shows promising results

Nile Therapeutics update on phase II CD-NP trial for acute heart failure

New Lantheus study finds significant survival benefit for critically ill patients undergoing contrast-enhanced echocardiography

Improved predictive value of biomarkers in HF makes earlier diagnosis and better management possible

Improved predictive value of biomarkers in heart failure now makes earlier diagnosis and better management possible

ARCA biopharma presents data from phase 3 BEST trial of Gencaro

A comparative analysis of four beta blocker trials

Updated heart failure guidelines focus on key research findings, clinical advances

Recently identified genetic heart disorder often deadly for young patients

Gilead commences phase II trial of Cicletanine for pulmonary arterial hypertension

Gleevec reduces risk of cancer returning in patients with life-threatening gastrointestinal stromal tumors

Set of criteria help identify candidates for combined heart and kidney transplants

New target for heart failure therapy identified

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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