Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

Bone marrow adult stem cells repair a damaged heart

Researchers at the McEwen Centre for Regenerative Medicine at Toronto General Hospital have discovered the 'SOS' distress signal that mobilizes specific heart repair cells from the bone marrow to the injured heart after a heart attack.

3 Jul 2006

New guidelines for treating high blood pressure discounts beta-blockers

Drug treatment for high blood pressure is set to undergo a major shake-up after new guidance was issued for the NHS.

28 Jun 2006

Quebec's first successful combined heart/liver transplant

Doctors at the McGill University Health Center have announced Quebec's first successful combined heart/liver transplant.

9 Jun 2006

HERA trial continues to demonstrate significant patient benefits from Herceptin

New 23-month follow-up data from HERA, one of the largest breast cancer trials ever carried out, show that Herceptin (trastuzumab) following standard chemotherapy significantly reduced the risk of death by 34% for women with early-stage HER2-positive breast cancer.

5 Jun 2006

Genes variations raise risk of heart disease after treatment for childhood cancer

Gene variations may raise the risk that survivors of childhood cancer will suffer congestive heart failure as a complication of drugs they received during cancer treatment.

5 Jun 2006

How low should our cholesterol be and just how safe are statins?

Experts in Sweden are warning that the new U.S. recommendations for lowering cholesterol levels would increase the risk of harmful side effects with no overall reduction in deaths.

4 Jun 2006

Pollution increases risks in people with diabetes, heart failure and other diseases

People with diabetes, heart failure, chronic obstructive pulmonary disease and inflammatory diseases such as rheumatoid arthritis are at increased risk of death when they are exposed to particulate air pollution, or soot, for one or more years.

23 May 2006

Common painkillers could up chance of heart failure in seniors

New research has revealed that commonly used over-the-counter painkillers, such as ibuprofen, are linked with a 30% increased risk of first hospital admission for heart failure.

22 May 2006

Arthritis drug wins approval for use in children with Crohn's disease

The Food and Drug Administration in the U.S. has given approval for the drug Remicade for use in children with active Crohn's disease(CD), a chronic and debilitating condition.

21 May 2006

Newly discovered gene MCPIP may lead to treatments for preventing inflammation that cause heart disease

A newly discovered gene known as MCPIP could provide scientists with the key to developing treatments for preventing inflammation that can cause heart disease, University of Central Florida researchers have discovered.

17 May 2006

Healthy habits and appropriate treatments help prevent stroke

Stroke is the third leading cause of death and a major source of disability in the United States. Every year about 700,000 people in the United States suffer a stroke, resulting in nearly 158,000 deaths.

10 May 2006

Corticosteroids may be linked to an increased risk for atrial fibrillation

High doses of medications known as corticosteroids may be linked to an increased risk for atrial fibrillation, a heart rhythm disorder characterized by an irregular heartbeat, according to an article in the May 8 issue of Archives of Internal Medicine.

9 May 2006

Cardiovascular disease impact varies according to age, gender, other factors

Cardiovascular disease deaths have declined in the last 25 years, but the effect of America's No. 1 killer varies greatly based on gender, age, location and type, according to a study reported in Circulation: Journal of the American Heart Association.

9 May 2006

Smokers more likely to receive jolt from defibrillators

If some patients with heart disease don't take their doctor's advice to quit smoking, they are probably going to get "shocking" reminders.

8 May 2006

Study helps explain why aerobic training helps heart failure patients

Aerobic training is associated with a reversal of abnormal hormonal patterns that underlie many of the debilitating symptoms of heart failure, according to a new study in the Journal of the American College of Cardiology.

3 May 2006

New drug lixivaptan reduces excess fluid build-up in patients with congestive heart failure

Researchers believe they may have identified a new agent to reduce the excess fluid build-up in patients with congestive heart failure, one that avoids the relative sodium-depleting effects of diuretics, now the most commonly used drugs for this purpose.

3 May 2006

Transplanted stem cells hoped to be able to regenerate damaged heart muscle in first heart attack victims

Rush cardiologists are hoping that transplanted stem cells can regenerate damaged heart muscle in those who experience a first heart attack. The study involves an intravenous infusion of adult mesenchymal stem cells from healthy donor bone marrow that might possibly reverse damage to heart tissue.

28 Apr 2006

Study indicates how drug efficacy can be increased by manipulating the signalling mechanism

Researchers believe they have found a way to change the action of 60 percent of currently available medications, in some cases making them many times more effective, according to an article published in the April 21 edition of the journal Science. The discovery has the potential to improve treatments for diseases including heart disease, cancer, diabetes, depression and arthritis. The study describes a new way to manipulate perhaps the most important signaling mechanism in human cells: G-protein coupled receptors (GPCRs).

28 Apr 2006

Study shows drugs work differently in the brains of men and women

A Johns Hopkins discovery could lead to tailored treatments for drug abuse and neurological diseases after providing what is believed to be the first evidence in people that amphetamines have a greater effect on men's brains than women's.

24 Apr 2006

Protein discovery opens up new therapeutic possibilities for epilepsy and neurodegenerative diseases

UC Irvine researchers have found that a protein best known for building connections between nerve cells and muscle also plays a role in controlling brain cell activity.

23 Apr 2006