Helicobacter pylori News and Research

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Researchers identify mechanisms through which H. pylori bacteria cause gastric cancer

Gastric cancer is one of the five most fatal types of cancer. According to the statistics of the World Health Organization, about 750,000 patients die each year after developing the disease. The main cause is thought to be the bacterium Helicobacter pylori (H. pylori).

7 Nov 2017

Prolonged use of PPIs linked with two-fold increased risk of stomach cancer, study finds

A new study published in the online journal Gut suggested that the prolonged use of proton pump inhibitors (PPIs) that are mainly utilized in treating acid reflux is associated with more than a two-fold increase in the risk of gastric cancer.

1 Nov 2017

Genetic variability of Helicobacter pylori complicates efforts to develop effective vaccine

Helicobacter pylori is a widespread bacterial pathogen that infects the lining of the stomach, where it can cause ulcers and even cancer. As a new study shows, its genetic variability complicates efforts to develop an effective vaccine.

25 Oct 2017

Research provides clues to how infectious bacteria may increase risk of cancer

Gastric carcinoma is one of the most common causes of cancer-related deaths, primarily because most patients present at an advanced stage of the disease.

17 Aug 2017

Nanobioelectronics to treat bacterial infection in the stomach

Nanotechnology has made another breakthrough at the University of California San Diego. For the first time the researchers have shown that micromotors or microscopic robots could be used to treat a bacterial infection in the stomach in mice models win the laboratory.

16 Aug 2017

Research reveals how bacteria may use mechanical cues to keep their shape

Bacteria come in all shapes and sizes -- some are straight as a rod, others twist like a corkscrew. Shape plays an important role in how bacteria infiltrate and attack cells in the body.

26 Jul 2017

Ondek raises capital to develop new treatment for childhood allergy

Ondek, the Australian biotechnology company founded by Nobel Laureate Professor Barry Marshall, today announced it raised A$3.59 million in equity funding from professional and high-net-worth investors to support his work to develop a new treatment for childhood allergy.

30 Jun 2017

Researchers find low adherence of physicians to H. pylori guidelines

It was long thought that gastric ulcers and other digestive woes were brought about by stress. But in 2005, clinical fellow Barry J. Marshall and pathologist J. Robin Warren were awarded the Nobel Prize in Physiology or Medicine for recognizing the role of Helicobacter pylori in gastritis and peptic ulcer disease.

15 Jun 2017

Study prompts further assessment of tomato extracts’ use in gastric cancer prevention

A new study shows that whole tomato extracts from two different Southern Italy cultivars inhibit gastric cancer cell growth and malignant features, paving the way for future studies aimed at implementing lifestyle habits not only for prevention but potentially as a support to conventional therapies.

15 May 2017

Scientists develop new drug that combats two ‘priority pathogens’

Scientists at St. Boniface Hospital Albrechtsen Research Centre and the University of Manitoba have developed a drug that combats 2 of the top 10 "priority pathogens" recently defined by the World Health Organization as antiobiotic-resistant bacteria requiring new interventions.

20 Apr 2017

Diagnosing Infections Through Molecules in Patient Breath

Over the past couple of decades, the analytical technology and the clinical microbiology insight needed to create a breath test for infections has seen a considerable number of advances and there are now numerous research teams focused on evaluating patient breath as a diagnostic fluid for infectious diseases. Significant challenges still need to be overcome.

From Pittcon 27 Feb 2017

Neutron analysis helps better understand key bacterial enzyme implicated in stomach cancer

Neutron analysis at the Department of Energy's Oak Ridge National Laboratory is helping researchers better understand a key enzyme found in a bacterium known to cause stomach cancer.

2 Feb 2017

Tiny 'submarines' could help treat stomach diseases with acid-sensitive drugs

Tiny “submarines” that speed independently through the stomach, use gastric acid for fuel (while rapidly neutralizing it), and release their cargo precisely at the desired pH: Though it may sound like science fiction, this is a new method for treating stomach diseases with acid-sensitive drugs introduced by scientists in the journal Angewandte Chemie.

24 Jan 2017

Could pathogen infection really lead to Alzheimer’s?

New concepts of infectious disease are evolving with the realization that pathogens are key players in the development of progressive chronic diseases that originally were not thought to be infectious. Infection is well-known to be associated with numerous neurological diseases for which...

12 Jan 2017

Scientists use pluripotent stem cells to generate human stomach tissues in laboratory

Scientists report in Nature using pluripotent stem cells to generate human stomach tissues in a petri dish that produce acid and digestive enzymes.

5 Jan 2017

Research sheds light on key genes essential to pathogenesis of Helicobacter pylori

Professor Frédéric Veyrier's most recent research, in collaboration with the team of Professor Hilde De Reuse at the Institut Pasteur, has shed light on key genes essential to the pathogenesis of Helicobacter pylori bacterium, which causes gastric infections.

21 Dec 2016

Researchers identify promising prospect for new medications to fight against H. pylori

There is a strong suspicion that Helicobacter pylori is linked to the development of stomach cancer. Now an international team of researchers led by Prof. Donald R. Ronning has used neutrons to unlock the secret to the functionality of an important enzyme in the bacterium's metabolism.

21 Dec 2016

Oral cavity bacterium linked to development and progression of esophageal cancer

A type of bacterium usually found in the human mouth, Fusobacterium nucleatum, has been found to be related to the prognosis of esophageal cancer in Japanese patients by researchers from Kumamoto University, Japan.

9 Dec 2016

Identifying foods that trigger IBS: an interview with Dr Bill Chey

IBS is a common medical condition which is diagnosed in the presence of characteristic gastrointestinal symptoms including recurring bouts of abdominal pain and diarrhea and/or constipation. IBS patients also commonly report bloating and abdominal distension or swelling.

15 Nov 2016

Scientists discover new receptors for stomach bacterium Helicobacter pylori

A research group led by Prof. Markus Gerhard of the Technical University of Munich and Assistant Professor Dr. Bernhard B. Singer of the Institute for Anatomy at the Faculty of Medicine of the University of Duisburg-Essen at Essen University Medical Centre has discovered a completely new approach to preventing or treating infections with this bacterium as well as secondary complications.

19 Oct 2016