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New shape of DNA found in human cells

DNA double helix discovery is one of the major breakthroughs in human scientific history. Now in a new research, scientists have found that there may be another new shape in the DNA machinery within the cells of humans.

25 Apr 2018

Scientists identify new DNA structure within living human cells

For the first time, a team of researchers have identified a new DNA structure inside cells that has an entirely different shape to the iconic “double helix” shape uncovered by Watson and Crick in 1953.

24 Apr 2018

New black Porvair Krystal UV Quartz microplates for Circular Dichroism measurements

Porvair Sciences introduces new black Krystal UV Quartz bottomed microplates that offer excellent optical transmission in the wavelength range 185 nm to 1100 nm making them ideal for labs looking to make Circular Dichroism (CD) measurements.

From Porvair Sciences Limited 17 Apr 2018

DNA-mimicking synthetic molecule could lead to new HIV treatment

Researchers have developed a synthetic compound that mimics the surface of DNA and is able to inhibit several DNA-processing enzymes.

4 Apr 2018

Wound protector use linked to statistically significant reduction in SSI, study shows

Surgical site infection is a common occurrence among patients who have had gastrointestinal surgery, with reported infection rates varying from 4 to 25 percent.

30 Mar 2018

Resolving Interfacial Protein Dynamics by STReM

STReM stands for Super Time-Resolved Microscopy, and as STORM, PALM, and other methods are designed to improve spatial resolution of optical microscopy, we desire to improve the time resolution. STReM makes use of point spread function engineering to encode fast events into each camera frame.

From Pittcon 16 Feb 2018

Study reveals the mechanism of common DNA mutations

Researchers at The Ohio University have uncovered the mechanism by which thymine and guanine, the most commonly mutated bases in DNA, become damaged.

2 Feb 2018

My grandmother was Italian. Why aren’t my genes Italian?

Maybe you got one of those find-your-ancestry kits over the holidays. You’ve sent off your awkwardly collected saliva sample, and you’re awaiting your results.

29 Jan 2018

DNA study sheds light on longstanding puzzle of cell division

Scientists have solved a longstanding puzzle of how cells are able to tightly package DNA to enable healthy cell division.

19 Jan 2018

A new strategy proposed for drug discovery

A joint industry/academia study of a cancer target protein reveals unusual relation between binding site flexibility and drug-target lifetime.

17 Jan 2018

Biomedical, Biophysical and Biological Applications of AFM

An interview with Dr. Thomas Mueller, Director of Product Management at Bruker Nano Surfaces conducted by April Cashin-Garbutt, MA (Cantab).

From Bruker Nano Surfaces and Metrology 10 Jan 2018

Genome editing approach prevents progressive hearing loss in animals

Using molecular scissors wrapped in a greasy delivery package, researchers have disrupted a gene variant that leads to deafness in mice.

20 Dec 2017

Stem cells remain healthy following low-dose X-ray exposure, say biophysicists

Biophysicists have shown that following low-dose exposure to X-rays (at 80 milligrays), stem cells remain healthy, proliferate, and do not accumulate DNA damage to be passed on to their progeny. The paper was published in the journal Aging.

20 Dec 2017

Advances in BioAFM

AFM is quite a versatile technique and we see a great potential of this technology for life science applications. It is still fairly new in Bio community, however very well accepted not only as imaging tools but as a versatile instrument for nanomechanical measurements.

From Bruker Nano Surfaces and Metrology 19 Dec 2017

Researchers adopt new approach to treating advanced prostate cancer

Scientists have proposed a new approach to preventing the proliferation of prostate tumor cells that are no longer responding to treatment. Prostate cancer can usually be cured via surgical removal of the tumor and/or the use of radiotherapy, but in one-fifth of cases, patients also require treatment with drugs to continue removing tumor cells. However, these drugs are only effective for up to three years, after which the cancer continues to develop.

13 Dec 2017

Researchers discover new way to attack drug-resistant prostate cancer cells

In most cases, prostate cancer is cured by surgical removal of the tumor and/or by radiotherapy. However, 20% of patients will need treatment to remove tumor cells but this treatment ceases to be effective after two or three years and the cancer develops further.

13 Dec 2017

Biological Applications of AFM

An interview with Samuel Lesko, European Applications Manager, Bruker Nano Surfaces conducted by April Cashin-Garbutt, MA (Cantab).

From Bruker Nano Surfaces and Metrology 5 Dec 2017

Research provides insight into how two stands of double helix separate during replication

Life would be impossible if the DNA in dividing cells were replicated with anything less than near-perfect precision. Every time a nucleated cell commits to becoming two cells, every "letter" of its genome must be replicated once and only once.

24 Oct 2017

Agilent collaborate with Doulix to promote SureVector cloning kits

Double Helix Technologies (Doulix) announced today a collaboration with Agilent Technologies Inc. to promote Agilent's SureVector next-generation cloning kits through Doulix’s web platform. Through this partnership, synthetic biologists will be able to choose among SureVector’s standard DNA parts to design custom plasmids using Doulix’s web platform.

From Agilent Technologies - Genomics 11 Oct 2017

“Chemical surgery” on embryos to free them of a gene causing thalassemia

A team of Chinese researchers have for the first time “mended” defective embryos using chemical surgery to free them of a faulty gene that leads to beta thalassemia. Until now this defect was found to be incorrigible caused due to a single misspelling in the DNA code. Beta thalassemia is a dreaded blood disorder wherein the child is unable to make healthy blood needing blood transfusions on a regular basis. The study was published this week in the journal Protein and Cell.

2 Oct 2017