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Two ACS members, editor of JACS to receive nation's highest honors in science and innovation

Peter J. Stang, Ph.D., editor of the Journal of the American Chemical Society (JACS), and American Chemical Society members Jacqueline K. Barton, Ph.D. and Rakesh Agrawal, Ph.D., are among 12 eminent researchers and inventors named by President Obama to receive the nation's highest honors in science and innovation.

30 Sep 2011

Researchers reveal crystal structure of dynamin protein

The crystal structure of the dynamin protein - one of the molecular machines that makes cells work - has been revealed, bringing insights into a class of molecules with a wide influence on health and disease.

19 Sep 2011

Biologists identify mechanism of H. pylori that damages DNA of gastric mucosal cells

The stomach bacterium Helicobacter pylori is one of the biggest risk factors for the development of gastric cancer, the third most common cause of cancer-related deaths in the world.

6 Sep 2011

DNA sequencing pioneer, two pharmaceutical researchers recognized as ACS 'Heroes of Chemistry'

Two scientists developed a new drug that helped pioneer the era of "personalized medicine" for cancer patients, an approach in which one-size-fits-all drugs yield to medicines customized to the genetic endowment of individual patients. Another scientist invented today's predominant technology for genetic sequencing, deciphering the genetic blueprint in the DNA that makes up the genes of living things.

30 Aug 2011

Scientists discover new bases of DNA

For decades, scientists have known that DNA consists of four basic units -- adenine, guanine, thymine and cytosine. Those four bases have been taught in science textbooks and have formed the basis of the growing knowledge regarding how genes code for life.

22 Jul 2011

Novel compound blocks signaling from protein implicated in many types of cancer

Researchers at New York University's Department of Chemistry and NYU Langone Medical Center have developed a compound that blocks signaling from a protein implicated in many types of cancer. The compound is described in the latest issue of the journal Nature Chemical Biology.

18 Jul 2011

U-M researchers a step closer to developing treatments for aging and chronic diseases

As our bodies first form, developing cells are a lot like children put on the school bus with their names and addresses pinned to their shirts. The notes identify one as a future heart cell, another as a liver cell, a third as a neuron. And that's what they each grow up to be. But once those cells reach adulthood, changes to those original marching orders caused by aging, disease and other stressors like smoking can precipitate a kind of identity crisis, researchers at the University of Michigan Health System have found.

2 Jul 2011

Researchers uncover protein structural clues associated to PD

Researchers at the Keck School of Medicine of the University of Southern California (USC) have uncovered structural clues about the protein linked to Parkinson's disease (PD), which ultimately could lead to finding a cure for the degenerative neurological disorder.

18 Jun 2011

Golden Helix integrates CMC and KBAC methods of analyzing rare DNA sequence variants in SVS product

Though two of the best-known methods for analyzing rare variants in sequencing data were published in 2008 and 2010, they have never been available to the public as a supported package.

21 May 2011

Multiple toxic mechanisms link elevated iron, copper levels in the brain and extensive DNA damage

No one knows the cause of most cases of Alzheimer's, Parkinson's and other neurodegenerative disorders. But researchers have found that certain factors are consistently associated with these debilitating conditions.

21 May 2011

Computationally designed antiviral proteins may fight against influenza

A research article May 12 in Science demonstrates the use of computational methods to design new antiviral proteins not found in nature, but capable of targeting specific surfaces of flu virus molecules.

16 May 2011

Helix BioMedix total revenue increases 413% to $358,000 for first quarter 2011

Helix BioMedix, Inc., a developer of bioactive peptides, today announced financial results for the company's first quarter ended March 31, 2011.

7 May 2011

FEN1 enzyme might serve as anti-cancer therapy target

An enzyme essential for DNA replication and repair in humans works in a way that might be exploited as anti-cancer therapy, say researchers at The Scripps Research Institute and Lawrence Berkeley National Laboratory.

15 Apr 2011

Rsearchers define new step that controls programmed cell death in cancer cells

When cells find themselves in a tight spot, the cell cycle regulator p21 halts the cell cycle, buying cells time to repair the damage, or if all else fails, to initiate programmed cell death.

2 Apr 2011

Loss of SKIP sensitizes cancer cells to apoptotic effects of DNA damage-inducing anticancer drugs

When cells find themselves in a tight spot, the cell cycle regulator p21 halts the cell cycle, buying cells time to repair the damage, or if all else fails, to initiate programmed cell death. In contrast to other stress-induced genes, which dispense with the regular transcriptional entourage, p21Cip1 still requires SKIP, a transcription elongation factor that also helps with the editing of transcripts, to be expressed, found researchers at the Salk Institute for Biological Studies.

2 Apr 2011

Helix BioMedix 2010 total revenue increases 118% to $852,000

Helix BioMedix, Inc., a developer of bioactive peptides, today announced financial results for the year ended December 31, 2010.

28 Mar 2011

New discovery provides insight into complex Rad50 molecular motor function

Over the last years, two teams of researchers at The Scripps Research Institute have steadily built a model of how a powerful DNA repair complex works. Now, their latest discovery provides revolutionary insights into the way the molecular motor inside the complex functions - findings they say may have implications for treatment of disorders ranging from cancer to cystic fibrosis.

28 Mar 2011

OrbusNeich launches CE marked Azule Cobalt Chromium Stent

OrbusNeich today announced the launch of the CE marked Azule Cobalt Chromium Stent. The Azule Stent combines the proven stent design of its predecessor, the company's Blazer™ Cobalt Chromium Stent, with a delivery system with enhanced crossability and flexible deliverability.

14 Mar 2011

Novel sortase-based techniques allow modification of a large variety of different proteins

Whitehead Institute scientists have created a method that site-specifically modifies proteins to exert control over their properties when administered therapeutically. The technique should be useful to increase potency, slow metabolism, and improve thermal stability of therapeutically useful proteins, such as interferon alpha 2 (IFN-alpha 2), which is used to treat variety of diseases, including leukemia, melanoma, and chronic hepatitis C.

10 Mar 2011

Novel study deepens understanding of how chromosome replication works

A novel study from the Swedish medical university Karolinska Institutet has deepened the understanding of how chromosome replication, one of life's most fundamental processes, works.

3 Mar 2011