Hematology News and Research

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Hematology, also spelled haematology, is the branch of biology (physiology), pathology, clinical laboratory, internal medicine, and pediatrics that is concerned with the study of blood, the blood-forming organs, and blood diseases. Hematology includes the study of etiology, diagnosis, treatment, prognosis, and prevention of blood diseases.

New gene therapy offers hope for beta thalassemia patients

UCSF Benioff Children's Hospital Oakland provides new therapy to first patient since FDA approval.

31 Aug 2023

Universal approach could potentially expand CAR T cell therapy to all blood cancers

A broad new strategy could hold hope for treating virtually all blood cancers with CAR T cell therapy, which is currently approved for five subtypes of blood cancer.

31 Aug 2023

New targeted therapy zolbetuximab extends survival for patients with advanced gastric cancer

An international phase 3 clinical trial, done in participation with Weill Cornell Medicine and NewYork-Presbyterian, found that a new targeted treatment called zolbetuximab, given in combination with a standard chemotherapy, extended survival for patients with advanced gastric or gastroesophageal junction cancer that overexpressed a specific biomarker.

23 Aug 2023

NCCN publishes new resource on options, benefits of care approaches for pediatric Hodgkin lymphoma

The National Comprehensive Cancer Network today announced the publication of NCCN Guidelines for Patients®: Hodgkin Lymphoma in Children.

22 Aug 2023

$2.8 million awarded to translate research on how cancer cells evolve and compete into patient care

The National Institutes of Health recently awarded Cleveland Clinic's Jacob Scott, M.D., D.Phil., and collaborators $2.8 million to translate research on how cancer cells evolve and compete into patient care.

22 Aug 2023

Medicaid expansion increases cancer clinical trial participation

The Medicaid expansion under the Patient Protection and Affordable Care Act resulted in a 19% annual increase in Medicaid-insured cancer patients participating in publicly funded clinical trials, according to researchers from Fred Hutchinson Cancer Center, the SWOG Statistics and Data Management Center and Columbia University.

18 Aug 2023

Rutgers scientists discover first lipid vascular 'zip code' in the lungs

Researchers at Rutgers Cancer Institute of New Jersey and Rutgers New Jersey Medical School (NJMS), together with other collaborating groups, have discovered the first lipid vascular 'ZIP code' in the lungs.

16 Aug 2023

Diverse gut microbiome may help children survive stem cell transplant

Researchers in Italy have shown for the first time that among children who have undergone a donor stem cell transplant, the presence of diverse species of micro-organisms in the intestinal tract before the transplant resulted in significantly better overall patient survival and fewer complications.

10 Aug 2023

Ovarian cancer patients enrolled in first-in-human trial of CAR T cell therapy

Recently published preclinical data by City of Hope scientists shows the immunotherapy is effective. Advanced ovarian cancer patients are now being enrolled in a Phase 1 first-in-human trial.

10 Aug 2023

Automated cell analysis with Haemorasis can help diagnose blood disorders

Scientists from the German Cancer Research Center (DKFZ) and the Cambridge Stem Cell Institute have developed an AI system that recognizes and characterizes white and red blood cells in microscopic images of blood samples.

10 Aug 2023

Adenovirus infection linked to rare blood clotting disorder

Platelets, or thrombocytes, are specialized cellular fragments that form blood clots when we get scrapes and traumatic injuries. Viral infections, autoimmune disease, and other conditions can cause platelet levels to drop throughout the body, termed thrombocytopenia.

10 Aug 2023

Research breaks ground on new ways of treating blood disorders with gene therapy

Research from experts at Michigan Medicine, the Children's Hospital of Philadelphia and Penn Medicine is breaking ground on new ways of treating blood disorders, such as sickle cell anemia, through gene therapy.

9 Aug 2023

Mice lacking TMCO3 gene have shortened bones

Through next-generation sequencing, investigators have identified a mutation in the TMCO3 gene in two sisters with short stature.

9 Aug 2023

Myelodysplastic syndromes are commonly misdiagnosed, study finds

Blood disorders known as myelodysplastic syndromes/neoplasms (MDS) are difficult to diagnose – and are commonly misdiagnosed – putting patients at increased risk for treatment mistakes and other potentially harmful consequences, according to researchers with Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine and collaborating organizations.

8 Aug 2023

Thymus gland critical for adult health, study finds

The thymus gland-; which produces immune T cells before birth and during childhood-; is often regarded as nonfunctional in adults, and it's sometimes removed during cardiac surgery for easier access to the heart and major blood vessels.

2 Aug 2023

New gene editing approach could revolutionize the treatment of blood disorders

In a step forward in the development of genetic medicines, researchers at Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania have developed a proof-of-concept model for delivering gene editing tools to treat blood disorders, allowing for the modification of diseased blood cells directly within the body.

27 Jul 2023

Lab-on-a-chip technologies offer new ways to assess stored red blood cells

Ziya Isiksacan, PhD, a research fellow in the Center for Engineering in Medicine and Surgery (CEMS) is the lead author, and Osman Berk Usta, PhD, an investigator in the CEMS at Massachusetts General Hospital and an associate professor of Surgery at Harvard Medical School, is the senior author of a new study published in PNAS, Assessment of Stored Red Blood Cells Through Lab-on-a-Chip Technologies for Precision Transfusion Medicine.

26 Jul 2023

Cancer-causing gene also plays a crucial role in aging, study finds

A gene called Myc (pronounced "mick") that is among the most important drivers of cancer in both mice and humans also plays a newly discovered crucial role in aging, according to a new Cell Reports study by researchers at UPMC Children's Hospital of Pittsburgh and the University of Pittsburgh School of Medicine.

24 Jul 2023

New lipid 'signature' could help identify women at risk of preeclampsia

University of Virginia School of Medicine researchers have discovered a way to identify pregnant women at risk of preeclampsia, a serious disorder characterized by high blood pressure and kidney dysfunction which can result in premature delivery, seizures and even death.

14 Jul 2023

Rethinking how cancer immunotherapy drugs are delivered could save millions

A new analysis finds that up to millions of dollars could be saved annually on cancer immunotherapy treatments across the Veterans Health Administration by reconsidering how those drugs are delivered.

11 Jul 2023