Hemoglobin News and Research

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Early metformin therapy falls short in curbing gestational diabetes woes

In a significant randomized clinical trial, early metformin therapy was tested for its potential to lessen insulin dependence and enhance glycemic control in gestational diabetes-afflicted pregnant women; however, it yielded no improvements in diabetes symptoms. While metformin reduced maternal weight gain, its effects on primary diabetes symptoms and other secondary outcomes like infant weight gain were mixed, indicating a need for further focused research to unravel these associations.

4 Oct 2023

The cut-off for HbA1c-based diagnosis of diabetes may be too high in women

Researchers compare the distribution of glycated hemoglobin (HbA1c) levels in premenopausal women and men of the same age.

4 Oct 2023

New hope for hispanic type 2 diabetes patients: pharmacist intervention cuts A1c levels

Researchers examined whether pharmacist-led interventions improved adherence to medications and guideline-concordant care based on changes in hemoglobin A1C (HbA1C) levels and systolic blood pressure among Hispanic type 2 diabetes patients.

3 Oct 2023

Sensors that monitor salivary metabolic changes to rapidly diagnose diabetes

A sensor for non-invasive glucose determination in body fluids such as saliva.

29 Sep 2023

Machine learning-based models can predict diabetes incidence across several ethnicities

Predicting diabetes mellitus type 2 (T2D) incidence and prevalence across differing ethnicities.

27 Sep 2023

How do different polyphenol-rich foods impact chronic diseases?

The potential of phytochemicals in promoting a healthy human diet to combat chronic disease.

27 Sep 2023

Breast cancer patients treated with alpelisib have elevated rates of high blood sugar

New research has uncovered elevated rates of high blood sugar, or hyperglycemia, among patients with breast cancer who are treated with the oral medication alpelisib.

25 Sep 2023

Diabetes incidence significantly increased among youth during COVID-19 pandemic

Diabetes incidence among youth in the United States before and during the coronavirus disease 2019.

25 Sep 2023

Tirzepatide outshines other treatments in lowering blood sugar and weight for type 2 diabetes patients

Meta-analysis finds tirzepatide to be the most effective GLP-1 receptor agonist for glucose and weight control in type 2 diabetes patients. The study suggests tirzepatide could be preferable in initial stages of the disease, while other GLP-1 receptor agonists combined with insulin are equally effective for long-term diabetics.

25 Sep 2023

Could metformin be a game changer for heart health in non-diabetics?

Using Mendelian randomization, researchers found that altering seven metformin targets led to improved blood pressure and BMI in non-diabetic individuals. The study suggests the potential for metformin's role in reducing cardiovascular risks in the general population, although more research is needed.

24 Sep 2023

Stuart Orkin receives the third Elaine Redding Brinster Prize for development of sickle cell disease therapy

For his work discovering the basis for hemoglobin gene switching and applying those insights to develop a therapy for sickle cell disease and other blood diseases, the Institute for Regenerative Medicine at the University of Pennsylvania awarded Stuart Orkin, MD the third Elaine Redding Brinster Prize in Science or Medicine.

15 Sep 2023

Evening chronotype linked to unhealthy lifestyles and increased diabetes risk, reveals cohort study

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12 Sep 2023

Machine learning uncovers hidden diabetic cases among those with normal fasting glucose

Researchers identified diabetic individuals among populations with normal fasting glucose using ML.

12 Sep 2023

Racial and ethnic inequities are substantial in type 2 diabetes after gestational diabetes, study shows

Racial and ethnic inequities in diabetes have been established following gestational diabetes, but these inequities are substantial and have been an overlooked facet of maternal health equity, according to a new study by epidemiologist Teresa Janevic, PhD, associate professor of Epidemiology at Columbia University Mailman School of Public Health. Until now there was limited research on racial and ethnic disparities in type 2 diabetes after gestational diabetes mellitus (GDM).

8 Sep 2023

The rise in anaemia among adolescent women in India: a comprehensive study on prevalence trends

In a recent study, researchers analyzed the change in the prevalence of anemia among adolescent women in India from 2015 to 2021.

7 Sep 2023

Eating for health: how dietary interventions impact pre-diabetic oral and gut microbiome, metabolites and cytokines

Researchers evaluated the impact of two diets on the intestinal and oral microbiota, cytokines, and metabolites of 200 pre-diabetic individuals.

7 Sep 2023

Does dahlia flower extract have anti-diabetic properties?

The effects of an extract of yellow petals of Dahlia pinnata as a novel treatment of type 2 diabetes (T2D).

6 Sep 2023

NGS-based screening identifies rare and novel thalassemia mutations in Ganzhou, China

Around 5.2% of the global population carries abnormal hemoglobin genes. Each year, 300,000 to 500,000 children are born with severe hemoglobinopathies worldwide, with approximately 80% of these cases occurring in developing countries.

5 Sep 2023

Gut microbes play a starring role in insulin resistance, opening doors for new diabetes treatments

The study reveals a strong association between gut microbial carbohydrate metabolism and insulin resistance, pointing to gut microbes as a key player in metabolic syndrome and type 2 diabetes. Targeting these microbial activities could offer a new therapeutic pathway for improving insulin resistance and overall metabolic health.

4 Sep 2023

Intensive fasting boosts red blood cells' immune powers against COVID-19, study finds

Researchers found that short-term intensive fasting enhances the immune function of red blood cells, including their ability to combat SARS-CoV-2, without affecting their oxygen-carrying capacity. The study reveals that this fasting regimen popular in Asia could offer a multifaceted benefit by amplifying the body's defenses without compromising essential functions.

4 Sep 2023

Hemoglobin News and Research

Early metformin therapy falls short in curbing gestational diabetes woes

The cut-off for HbA1c-based diagnosis of diabetes may be too high in women

New hope for hispanic type 2 diabetes patients: pharmacist intervention cuts A1c levels

Sensors that monitor salivary metabolic changes to rapidly diagnose diabetes

Machine learning-based models can predict diabetes incidence across several ethnicities

How do different polyphenol-rich foods impact chronic diseases?

Breast cancer patients treated with alpelisib have elevated rates of high blood sugar

Diabetes incidence significantly increased among youth during COVID-19 pandemic

Tirzepatide outshines other treatments in lowering blood sugar and weight for type 2 diabetes patients

Could metformin be a game changer for heart health in non-diabetics?

Stuart Orkin receives the third Elaine Redding Brinster Prize for development of sickle cell disease therapy

Evening chronotype linked to unhealthy lifestyles and increased diabetes risk, reveals cohort study

Machine learning uncovers hidden diabetic cases among those with normal fasting glucose

Racial and ethnic inequities are substantial in type 2 diabetes after gestational diabetes, study shows

The rise in anaemia among adolescent women in India: a comprehensive study on prevalence trends

Eating for health: how dietary interventions impact pre-diabetic oral and gut microbiome, metabolites and cytokines

Does dahlia flower extract have anti-diabetic properties?

NGS-based screening identifies rare and novel thalassemia mutations in Ganzhou, China

Gut microbes play a starring role in insulin resistance, opening doors for new diabetes treatments

Intensive fasting boosts red blood cells' immune powers against COVID-19, study finds

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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