Viral hemorrhagic fevers (VHFs) refer to a group of illnesses that are caused by several distinct families of viruses. In general, the term "viral hemorrhagic fever" is used to describe a severe multisystem syndrome (multisystem in that multiple organ systems in the body are affected). Characteristically, the overall vascular system is damaged, and the body's ability to regulate itself is impaired. These symptoms are often accompanied by hemorrhage (bleeding); however, the bleeding is itself rarely life-threatening. While some types of hemorrhagic fever viruses can cause relatively mild illnesses, many of these viruses cause severe, life-threatening disease.
Researchers described the Marburg virus (MARV) July 2022 outbreak in Ghana and efforts globally to curtail MARV transmission.
A modified tuberculosis (TB) vaccine developed at Texas Biomed could help treat a form of bladder cancer, called non-muscle invasive bladder cancer, without strong side effects.
Ghana announced the country’s first Marburg virus disease outbreak, after receiving a confirmatory report of the disease from the World Health Organization’s (WHO) Collaborating Centre Laboratory.
Researchers at the University of Texas Medical Branch have achieved success with a new vaccine developed to fight Lassa Virus, a pathogen that causes Lassa fever.
As the coronavirus waves keep coming and cases are on the rise once again, the National Institutes of Health (NIH) recently launched a $577 million effort to develop antivirals against COVID-19 and other viruses with high pandemic potential.
A new study published as a pre-proof in the journal Virologica Sinica, is follow-up research to a previous study on the discovery of novel rodent viruses of various RNA viral families in Kenya.
Army scientists determined that the body's own natural immune response contributes to disease severity in mice infected with Crimean-Congo hemorrhagic fever virus (CCHFV), which causes a widespread tick-borne viral infection in humans.
Researchers discuss the development and structural characterization of therapeutic monoclonal antibodies targeting the surface glycoprotein of filoviruses.
Since the onset of the coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), scientists have been conducting extensive studies to understand various aspects of the virus. Researchers have stated that SARS-CoV-2 manifests several biological and clinical consequences of a superantigen
As SARS-CoV-2 has continued to evolve and outsmart existing treatments, scientists have not let up looking for ever-more effective tools to keep people safe and successfully recover from COVID-19, and to prepare for future outbreaks.
Briefly blocking a key molecule when administering the only approved vaccine for tuberculosis vastly improves long-term protection against the devastating disease in mice, researchers from Texas Biomedical Research Institute report this week in the Journal of Immunology.
A team of scientists from Germany has recently conducted a serological screening on wild animals to assess seroprevalence against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and other pathogenic viruses related to domestic ruminants.
What is going on at the single-cell level in the first days of SARS-CoV-2 infection in the lungs?
In new research, scientists from the Beijing University of Technology have been investigating the impact of the COVID-19 pandemic on the incidence and mortality of zoonotic diseases in China. Their work is published in the journal BMJ Global Health.
Independent teams from Texas Biomedical Research Institute and the Medical College of Wisconsin have published two papers in Science Translational Medicine identifying how the only approved drug to treat schistosomiasis, a widespread parasitic worm infection, works on the molecular level.
Can the COVID-19 delta variant evade vaccine-induced immunity? We spoke to Professor Brian J. Willett from the University of Glasgow to find out.
A new review aimed to describe the current state of knowledge on Sialodacryoadenitis virus, along with its characteristics and potential zoonotic threat.
Understanding how malaria parasites evolve after a human is bitten by an infected mosquito is very difficult. There can be billions of individual parasites in a patient's bloodstream and traditional genetic sequencing techniques can't identify the raw material for evolution: new mutations.
During the pandemic, it has become increasingly evident that people with cardiovascular disease and obesity are at a much higher risk of developing very severe, even fatal COVID-19 disease.
A version of SARS-CoV-2, the virus that causes COVID-19 disease, has been successfully modified to glow brightly in cells and animal tissues, providing a real-time way to track the spread and intensity of viral infection as it happens in animal models, researchers at Texas Biomedical Research Institute report in the journal The Proceedings of the National Academy of Sciences.