Hepatocellular Carcinoma News and Research

RSS

Hepatocellular Carcinoma is a type of adenocarcinoma, the most common type of liver tumor.

World Hepatitis Day 2022: Why Accelerating the Fight Against Hepatitis Cannot Wait

In our latest interview, News-Medical speaks to Simon Parker, an infectious disease specialist, about hepatitis C diagnostics and testing, as well as why the global fight against hepatitis cannot wait.

28 Jul 2022

Constant activation of p53 in hepatocytes of CLD patients could promote the development of liver cancer

p53 is one of the most important proteins in cancer biology. Often referred to as a "guardian of the genome," p53 becomes activated in response to various cellular stressors like DNA damage.

12 Jul 2022

Inhibiting pore formation in cells may facilitate prevention, treatment of NASH-associated liver cancer

Need another reason to think twice before ordering that extra helping of fries? It could lead to a higher risk of developing liver cancer.

24 Jun 2022

Simple blood test can predict liver cancer risk in NAFLD patients

An estimated one-quarter of adults in the U.S. have nonalcoholic fatty liver disease (NAFLD), an excess of fat in liver cells that can cause chronic inflammation and liver damage, increasing the risk of liver cancer.

22 Jun 2022

Targeting macropinocytosis may be an effective therapeutic approach for hepatocellular carcinoma

Researchers from the Department of Pathology, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong (HKUMed) have identified a new metabolic mechanism in liver cancer cells, by which macropinocytosis, an endocytic process, is used to engulf extracellular proteins as fuels to support the unlimited growth of hepatocellular carcinoma (HCC) in hypoxia (oxygen deprivation).

14 Jun 2022

Benefits and limitations of non-invasive tests for diagnosing non-alcoholic fatty liver disease

Non-alcoholic fatty liver disease (NAFLD) is among the most prevalent chronic liver disorders worldwide and can sometimes lead to severe conditions like cirrhosis and hepatocellular carcinoma.

2 Jun 2022

Study shows the SARS-CoV-2 accessory protein ORF7a inhibits HLA-I surface expression levels in human cells

Researchers identified a single viral gene product, the accessory factor ORF7a, facilitating SARS-CoV-2 immune evasion by downregulating the surface expression of MHC class I molecules.

1 Jun 2022

Perceived stigmatization is common among patients with NAFLD, study finds

About seven out of ten patients (69%) who suffer from non-alcoholic fatty liver disease (NAFLD) perceive some stigmatization in their daily life, according to a study led by a team of the University of Barcelona, the Liver and Digestive Diseases Networking Biomedical Research Centre, the Hospital Clínic de Barcelona and the August Pi i Sunyer Biomedical Research Institute.

12 May 2022

CRISPR/Cas9 deletions induce adverse on-target genomic effects

Researchers utilized a CRISPR/Cas9 system to evaluate the usage of tRNA by deleting two tRNA genes from the genomes of hyper hepatocellular carcinoma and human near-haploid chronic myeloid leukemia cells.

27 Apr 2022

Novel targets for treating sorafenib-resistant hepatocellular carcinoma found using CRISPR-Cas9 screening

This study is led by Xiujun Cai (Department of General Surgery, Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine). Professor Xiujun Cai's research team screened the whole genome of hepatocellular carcinoma cells (HepG2) through CRISPR / cas9 system under sorafenib treatment, and screened the dominant gene in sorafenib resistance.

20 Apr 2022

Research shows tsRNA as a promising biomarker for early diagnosis of hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is the most primary liver cancer. It is one of the most common and mortal cancer worldwide, especially in East Asia. Advanced HCC patients expect a significantly low 5-year survival rate as well as poor prognosis.

18 Apr 2022

UCL researchers boost the effectiveness of therapeutic vaccine for chronic HBV

Scientists at UCL have significantly boosted the effectiveness of a therapeutic vaccine designed to control chronic hepatitis B (HBV) infection, after uncovering and thwarting 'the enemy within'.

13 Apr 2022

New trial aims to test a non-invasive treatment for early-stage liver cancer

Researchers are set to trial a non-invasive treatment for inoperable early-stage liver cancer, thanks to an injection of over $2 million in federal government funding.

25 Feb 2022

International Aspirin Foundation publishes a report on the work of highly commended investigators

The International Aspirin Foundation has published a report of the Winner and Highly Commended awardees, present at the prestigious Emerging Aspirin Investigator Award Ceremony.

18 Feb 2022

Researchers generate stable cell lines capable of producing various hepatitis B virus genotypes

A new study created stable cell lines capable of producing different genotypes of the hepatitis B virus (HBV), advancing understanding of each type's distinct virological features, treatment responses, and infectivity that could lead to new therapies against a virus infecting humans as far back as 4,500 years ago.

15 Feb 2022

Hepatocellular Carcinoma News and Research

Further Reading

World Hepatitis Day 2022: Why Accelerating the Fight Against Hepatitis Cannot Wait

Constant activation of p53 in hepatocytes of CLD patients could promote the development of liver cancer

Inhibiting pore formation in cells may facilitate prevention, treatment of NASH-associated liver cancer

Simple blood test can predict liver cancer risk in NAFLD patients

Targeting macropinocytosis may be an effective therapeutic approach for hepatocellular carcinoma

Benefits and limitations of non-invasive tests for diagnosing non-alcoholic fatty liver disease

Study shows the SARS-CoV-2 accessory protein ORF7a inhibits HLA-I surface expression levels in human cells

Perceived stigmatization is common among patients with NAFLD, study finds

CRISPR/Cas9 deletions induce adverse on-target genomic effects

Novel targets for treating sorafenib-resistant hepatocellular carcinoma found using CRISPR-Cas9 screening

Research shows tsRNA as a promising biomarker for early diagnosis of hepatocellular carcinoma

UCL researchers boost the effectiveness of therapeutic vaccine for chronic HBV

New trial aims to test a non-invasive treatment for early-stage liver cancer

International Aspirin Foundation publishes a report on the work of highly commended investigators

Researchers generate stable cell lines capable of producing various hepatitis B virus genotypes

Researchers find a way to interfere with the energy pathway that promotes liver cancer spread

Researchers develop new tool to determine patients' liver cancer risk after hepatitis C

Scientific review highlights the impact of coffee on digestive organs

New pathways responsible for hepatocellular carcinoma identified

ASTRO provides new guidance on the use of external beam radiation therapy for primary liver cancers

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

Latest News