Herceptin News and Research

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UCI makes tremendous strides in prevention, early detection and treatment of cancer

Like most people, John Gifford wasn't looking forward to a colonoscopy when he arrived on the UCI Medical Center campus in Orange in 2018.

23 Feb 2020

Treatment combination improves survival in advanced HER2-positive breast cancer patients

Researchers from The University of Texas MD Anderson Cancer Center today reported study results showing the addition of tucatinib to capecitabine (Xeloda) and trastuzumab (Herceptin) significantly improved progression-free survival (PFS) and overall survival (OS) in patients with advanced HER2-positive breast cancer, with and without brain metastasis according to results of the HER2CLIMB clinical trial.

11 Dec 2019

New research shows significant gaps in deployment of 'coverage with evidence development'

Value in Health, the official journal of ISPOR- the professional society for health economics and outcomes research, announced today the publication of new research from The Netherlands showing important gaps in the deployment of "coverage with evidence development," a type of pharmaceutical managed entry agreement that gives patients access to treatments while additional evidence is being collected.

15 Jul 2019

Chemotherapy can wreak havoc on the heart

Cheryl Krafft was diagnosed with an aggressive form of non-Hodgkin's lymphoma and was put on a very high-powered chemotherapy regimen to rid her body of the cancer. What she was not counting on was the chemotherapy causing another equally deadly problem.

21 Jun 2019

Study uncovers new oncogenic function of receptor associated with Alzheimer's disease

Common and rare SORLA single nucleotide polymorphisms have been associated with the development of Alzheimer's disease.

28 May 2019

Hundreds of new anti-cancer drug targets identified using CRISPR

A team of scientists from the Wellcome Sanger Institute have identified the genes that are essential for the survival of thirty types of cancer cells.

11 Apr 2019

Medication could mitigate side effects of chemotherapy for breast cancer patients

Researchers at the Stanford University School of Medicine have demonstrated a method of forecasting which breast cancer patients will suffer heart problems from a commonly used chemotherapy drug.

14 Mar 2019

New research finds how cancer cells acquire resistance to molecular-targeted drugs

Although molecular-targeted drugs have been known to show high efficacy to lung cancer patients, they also have limitations due to acquiring resistance to the drug used.

25 Feb 2019

Study shows precision medicines could aid more breast cancer patients via RNA-targeting

When women or men receive the worrisome diagnosis of breast cancer, that news comes with an important piece of information, namely, whether their cancer is HER2-positive or HER2-negative.

8 Feb 2019

Genetically modified chickens could soon lay eggs containing certain medications

In breakthrough research, a team of scientists from University of Edinburgh’s Roslin Institute, have genetically modified chicken to lay eggs that contain medications for arthritis and some cancers.

28 Jan 2019

Hens that lay human proteins in eggs offer cost-effective method of producing new drugs

Chickens that are genetically modified to produce human proteins in their eggs can offer a cost-effective method of producing certain types of drugs, research suggests.

28 Jan 2019

Researchers identify potential target for new breast cancer treatments

Researchers from the School of Basic & Medical Biosciences have identified a potential target that could lead to new treatments for triple negative breast cancer.

18 Dec 2018

New anti-HER2 drug shows promising anti-tumor activity in gullet, stomach and bowel cancers

An antibody that binds simultaneously to two distinct regions of the HER2 receptor to block the growth of cancer cells has shown promising signs of anti-tumor activity in a number of cancers including those of the gullet (esophagus), stomach and bowel.

14 Nov 2018

European Commission approves Pfizer’s first oncology biosimilar

Pfizer Inc. today announced the European Commission has approved TRAZIMERA, a biosimilar to Herceptin (trastuzumab), for the treatment of human epidermal growth factor overexpressing breast cancer and HER2 overexpressing metastatic gastric or gastroesophageal junction adenocarcinoma.

31 Jul 2018

Researchers investigate new treatment that is effective against recurrent breast cancers

What do one in five breast cancers have in common? Large amounts of a protein called HER2 (or human epidermal growth factor receptor 2).

30 Jul 2018

New combination approach may help crush resistance to treatment in lung cancer patients

New-generation lung cancer drugs have been effective in a large number of patients, but within about a year, the patients tend to develop resistance to the therapy.

26 Jul 2018

Altering bacteria’s genetic code may pave way for long-lasting drugs, shows study

By altering the genetic code in bacteria, researchers at The University of Texas at Austin have demonstrated a method to make therapeutic proteins more stable, an advance that would improve the drugs' effectiveness and convenience, leading to smaller and less frequent doses of medicine, lower health care costs and fewer side effects for patients with cancer and other diseases.

5 Jun 2018