High Cholesterol News and Research

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Obstructive sleep apnea and sudden cardiac death

After studying the sleep characteristics of nearly 11,000 adults in an overnight sleep laboratory, Mayo Clinic researchers suggest that obstructive sleep apnea (OSA) - and, in particular, the low nighttime oxygen saturation of the blood it causes - may be a risk factor for sudden cardiac death (SCD).

10 Nov 2008

Low levels of potassium in diet linked to high blood pressure

As a risk factor for high blood pressure, low levels of potassium in the diet may be as important as high levels of sodium - especially among African Americans, according to research being presented at the American Society of Nephrology's 41st Annual Meeting and Scientific Exposition in Philadelphia, Pennsylvania.

10 Nov 2008

Prevalence of metabolic syndrome and associated risk factors in Illinois

Adopting daily exercise sessions and a calcium-rich diet could reduce the risk of a group of health risk factors called the metabolic syndrome, finds a new study of Illinois adults.

7 Nov 2008

GlaxoSmithKline believes there is no liver safety issue with Avandia (rosiglitazone maleate)

GlaxoSmithKline today issued the following response to a petition filed by Public Citizen to the U.S. Food and Drug Administration (FDA) on Avandia (rosiglitazone maleate), a highly effective therapy for treating type 2 diabetes when used in the appropriate patient population.

31 Oct 2008

Mylan confirms generic Lescol patent challenge

Mylan Inc. has confirmed that the company and its subsidiary, Mylan Pharmaceuticals Inc., have been sued by Novartis in connection with Fluvastatin Capsules USP, 20 mg (base) and 40 mg (base), the generic version of Novartis' Lescol(R) Capsules.

22 Oct 2008

Statin-induced muscle disorders are focus of $2.5 million in grants from NIH

Approximately 200,000 of the 38 million people in the U.S. who take statins to treat high cholesterol may develop life-threatening muscle disease.

2 Oct 2008

Cholesterol research, begun in the 'Little Skate,' Garners Award

New research on the way the body processes cholesterol has earned a scientist at the University of Rochester Medical Center one of the highest honors in the field.

2 Oct 2008

Existing anti-obesity drugs may be effective against flu, hepatitis and HIV

Viruses dramatically increase cellular metabolism, and existing anti-obesity drugs may represent a new way to block these metabolic changes and inhibit viral infection, according to a study published today in the journal Nature Biotechnology.

29 Sep 2008

Gene variant boosts risk of fatty liver disease

Researchers at UT Southwestern Medical Center have found that individuals who carry a specific form of the gene PNPLA3 have more fat in their livers and a greater risk of developing liver inflammation.

25 Sep 2008

Oversize waistlines are a potent risk factor for heart disease in women

A heart expert at Johns Hopkins is calling for all women with a waistline measuring more than 35 inches to get an annual check-up and detailed risk assessment for heart problems because excess abdominal fat, even in the mildly obese and overweight, leads more than a third of women to underestimate their lifetime risk of having a heart attack, stroke or chest pain (angina).

24 Sep 2008

Experts say thousands at risk for heart disease go unchecked

Australian experts say thousands at risk for heart disease go unchecked and are not getting the drugs which protect them.

15 Sep 2008

Depressed dialysis patients more likely to be hospitalized or die, researcher finds

Dialysis patients diagnosed with depression are nearly twice as likely to be hospitalized or die within a year than those who are not depressed, a UT Southwestern Medical Center researcher has found.

14 Sep 2008

Clean teeth could save your life!

The researchers from the University of Otago, Dunedin, have discovered a new link between gum disease and heart disease which adds to a substantial body of research linking gum disease with heart disease and stroke.

11 Sep 2008

Bariatric surgery cost-effective for treating obesity

Health insurers can offset the cost of laparoscopic or traditional bariatric surgery as a weight-loss treatment for obese patients within two to four years as a result of savings on other medical costs, according to a study published this month in the American Journal of Managed Care, the Wall Street Journal reports.

9 Sep 2008

Discovery of new link between gum disease and heart disease

Heart disease is the leading cause of death worldwide. However, many people with cardiovascular disease have none of the common risk factors such as smoking, obesity and high cholesterol. Now, researchers have discovered a new link between gum disease and heart disease that may help find ways to save lives, scientists heard today (Tuesday 9 September 2008) at the Society for General Microbiology's Autumn meeting being held this week at Trinity College, Dublin.

8 Sep 2008

High cholesterol levels drop naturally in children on high-fat antiseizure diet

Elevated cholesterol levels return to normal or near normal levels over time in four out of 10 children with uncontrollable epilepsy treated with the high-fat ketogenic diet, according to results of a Johns Hopkins Children's Center study reported in the Journal of Child Neurology.

26 Aug 2008

Study reveals how blood flow force protects against atherosclerosis

Machines on cell surfaces, mechanical and lifeless as bed springs, protect blood vessels by responding to blood flow force, according to research published today in the Journal of Cell Biology. By sensing and reacting to force, such machines interfere with inflammatory pathways central to atherosclerosis, the cause of clogged arteries that lead to heart attack and stroke, the authors said. The next set of studies, already underway, seeks to "tweak" the process with the goal of designing a new class of therapies.

25 Aug 2008

Designer RNA fights high cholesterol, medical researchers find

Small, specially designed bits of ribonucleic acid (RNA) can interfere with cholesterol metabolism, reducing harmful cholesterol by two-thirds in pre-clinical tests, according to a new study by researchers at UT Southwestern Medical Center in collaboration with Alnylam Pharmaceuticals and the Massachusetts Institute of Technology.

11 Aug 2008

Statins reduce the risk of dementia by half

People at high risk for dementia who took cholesterol-lowering statins are half as likely to develop dementia as those who do not take statins, a new study shows.

28 Jul 2008

Amyloid plaques seen with conventional MRI in animal model for first time

For the first time, scientists have captured images of brain lesions similar to those found in Alzheimer's disease using clinical-grade MRI in an animal model of the disease, according to research reported at the Alzheimer's Association's 2008 International Conference on Alzheimer's Disease (ICAD 2008), in Chicago.

27 Jul 2008