High Performance Liquid Chromatography (HPLC) News and Research

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UPM researchers study stability of arsenic species in edible marine algae

Researchers at UPM have studied the stability of diverse arsenic species found in edible marine algae and have established the best conditions for their storage and preservation.

20 Jan 2015

BIOCRATES launches first-ever bile acids kit based on targeted metabolite quantitation

Austrian BIOCRATES Life Sciences AG, internationally renowned developer and marketer of innovative targeted metabolomics solutions, further expands its range of metabolomics-based kits with the addition of its assay for the determination of endogenous bile acids, allowing a panel of up to 19 analytes to be simultaneously quantitated from a single 10 µL sample of human or mouse plasma.

1 Sep 2014

Advion introduces high performance liquid chromatography to complement its CMS

Advion, Inc., a leading systems and consumables developer for the life sciences industry, introduces an affordable high performance liquid chromatography system to complement its line of expression compact mass spectrometers (CMS). Introduced in 2012, the CMS has been met with glowing reviews from the global synthetic organic chemistry market. With hundreds of CMS purchased and installed, this latest introduction offers a complete solution for those needing separation capabilities at an affordable price.

From Advion 7 Aug 2014

Zhichan decoction promotes dopaminergic neurons following NSC transplantation in PD rats

There is an increasing interest in Parkinson's disease (PD) treatment by increasing dopamine content and reducing dopaminergic metabolites in the brain.

17 Jul 2014

Urine test separates nonadherent from treatment-resistant hypertensive patients

Researchers have used a urine test to show that about a quarter of patients with supposedly treatment-resistant hypertension are actually failing to take their medications as prescribed.

22 Apr 2014

Staphylococcus Aureus Bacteria anticipates and turns immune defenses against the host

Around 20 percent of all humans are persistently colonized with Staphylococcus aureus bacteria, a leading cause of skin infections and one of the major sources of hospital-acquired infections, including the antibiotic-resistant strain MRSA.

20 Nov 2013

Scientists identify dangerous amount of methamphetamine analog in workout supplement Craze

An international team of scientists have identified potentially dangerous amounts of methamphetamine analog in the workout supplement Craze, a product widely sold across the U.S. and online.

15 Oct 2013

New paper advances scientific understanding of glycoproteins’ structure and function

A Simon Fraser University chemist is the lead author on a new paper that advances scientific understanding of the structure and function of glycoproteins, in particular the number and positioning of sugars on them.

14 Feb 2013

New research finds bisphenol A in fetal liver tissues

New research from the University of Michigan School of Public Health found BPA, or bisphenol A, in fetal liver tissue, demonstrating that there is considerable exposure to the chemical during pregnancy.

4 Dec 2012

Scientists develop new micropump for hand-held medical devices

In an advance toward analyzing blood and urine instantly at a patient's bedside instead of waiting for results from a central laboratory, scientists are reporting development of a new micropump capable of producing pressures almost 500 times higher than the pressure in a car tire. Described in ACS' journal Analytical Chemistry, the pumps are for futuristic "labs-on-a-chip," which reduce entire laboratories to the size of a postage stamp.

1 Nov 2012

Plasma D-serine levels reduced in schizophrenia

Patients with schizophrenia exhibit significantly lower plasma levels of the amino acid D-serine than mentally healthy individuals, Brazilian researchers report.

18 Oct 2012

Kynurenic acid levels increased in bipolar patients with psychotic features

Bipolar disorder patients with a history of psychotic features have higher cerebrospinal fluid concentrations of kynurenic acid (KYNA) than those without such features, research shows.

9 Oct 2012

PRISM technique as accurate as ELISAs in identifying proteins within biological samples

Combining two well-established analytic techniques and adding a twist identifies proteins from blood with as much accuracy and sensitivity as the antibody-based tests used clinically, researchers report this week in Proceedings of the National Academy of Sciences Early Edition online.

4 Sep 2012

Population Genetics validates GenomePooling™ for cancer

Population Genetics Technologies Ltd., creator of innovative methods for genetic analyses and biomarker discovery, has successfully completed a pilot study to prove that its GenomePooling™ method is sensitive and accurate enough to detect even small percentages of gene variants within cancer tissue. This validates the method’s suitability for use in IntReALL 2010, the world’s largest genetic analysis of acute lymphoblastic leukaemia (ALL) relapse cases. ALL is the most common childhood malignant disease.

31 Jul 2012

GenomePooling™ method is sensitive and accurate

31 Jul 2012

Arsenic exposure impairs semen quality

Environmental exposure to arsenic significantly reduces semen quality in Chinese men, research shows.

18 Jul 2012

Abbott announces CE Marking for ARCHITECT HbA1c assay

More than 346 million people worldwide are living with diabetes, and the World Diabetes Foundation estimates that number will increase by nearly 27 percent by 2030. In order to help physicians appropriately monitor treatment efficacy for these patients, Abbott announced today CE Marking (Conformite Europeenne) for the Abbott ARCHITECT HbA1c (IA) Assay.

10 Jul 2012

Rapid test to identify patients not responding to painkiller tramadol

French researchers have found a way to identify quickly the 5-10% of patients in whom the commonly used painkiller, tramadol, does not work effectively. A simple blood test can produce a result within a few hours, enabling doctors to switch a non-responding patient on to another painkiller, such as morphine, which will be able to work in these patients.

11 Jun 2012

Simple blood test can quickly identify 'poor metabolisers'

11 Jun 2012

BIOCRATES Life Sciences to introduce AbsoluteIDQ p180 and p150 research kits

Austrian BIOCRATES Life Sciences AG, prime developer of state-of-the-art metabolite biomarker panels, is about to launch new editions of two of its well-established research kit products -AbsoluteIDQ p180 and p150.

21 May 2012