High Throughput News and Research

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Curing canine cancer - human cancer benefit

One of the major issues associated with longer life expectancy in man and his best friend is an increase in the incidence of cancer.

13 Jul 2007

Chromosome linked to colorectal cancer identified

Researchers at the Ontario Institute for Cancer Research and Cancer Care Ontario have successfully identified a specific genetic variation on chromosome 8 that is associated with colorectal cancer.

9 Jul 2007

Discovery of IKBKE gene linked to breast cancer

Using a novel three-part screening process, scientists at Dana-Farber Cancer Institute have identified a gene that is made inappropriately in about a third of all breast cancers.

17 Jun 2007

BioGenex settles patent case with Ventana

BioGenex Laboratories announced a settlement of patent litigation with Ventana Medical Systems (VMSI), ending the dispute between the two companies.

3 Jun 2007

Largest ever Affymetrix GeneChip Microarray study

The Virginia Bioinformatics Institute (VBI) at Virginia Tech has announced that it has completed the largest ever Affymetrix GeneChip Microarray study for a plant experimental system in an academic research setting.

28 May 2007

Newly discovered WU virus may explain some respiratory infections

An ongoing effort to identify the microorganisms that make us sick has discovered a new virus potentially linked to unexplained respiratory infections.

18 May 2007

Study of unexplained respiratory infections leads researchers to new virus

An ongoing effort to identify the microorganisms that make us sick has discovered a new virus potentially linked to unexplained respiratory infections.

17 May 2007

Radically different approach to nuclear magnetic resonance

Detecting the molecular structure of a tiny protein using nuclear magnetic resonance (NMR) currently requires two things: a million-dollar machine the size of a massive SUV, and a large sample of the protein under study.

16 May 2007

Lab-on-a-chip speeds proteomics research

In recent years, the science of biology has been dominated by genomics, the study of genes and their functions.

4 May 2007

New automated test for gene mutations causing fragile X syndrome

A new automated test could enable population screening to identify carriers of the gene mutations causing fragile X syndrome (FXS), the most common inherited form of mental retardation, reports a study in the April issue of Genetics in Medicine, published by the American College of Medical Genetics and Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

19 Apr 2007

More effective therapies for individual cancers - personalized medicine

Genetic and epigenetic variations ensure that no two people are exactly alike, and the same holds true for any two cancers.

18 Apr 2007

Massive gene screening points way to more effective chemotherapy

Using a technology that can quickly screen all 20,000-plus human genes for biological activity, scientists have isolated 87 genes that seem to affect how sensitive human cancer cells are to certain chemotherapy drugs.

12 Apr 2007

Transgenomic signs contract with OSI Pharmaceuticals for cancer genetic analysis

Transgenomic has announced that it has signed a contract with OSI Pharmaceuticals to complete an analysis of specific cancer pathway genes.

11 Apr 2007

Six centers of excellence for influenza research and surveillance established in U.S.

The National Institute of Allergy and Infectious Diseases (NIAID) has announced it is awarding $23 million per year for seven years to establish six Centers of Excellence for Influenza Research and Surveillance.

2 Apr 2007

First time observing real-time molecular interplay within ribosome

The ribosome is a kind of factory for protein in the cell, and as such has long been a prime target for drug discovery. Now, a technological advance by a team at Weill Cornell Medical College is poised to revolutionize research in the field.

21 Mar 2007

Lilly to acquire neuroscience drug discovery co. Hypnion

Eli Lilly and Company and Hypnion, Inc. today announced that they have signed a definitive merger agreement whereby Lilly will acquire Hypnion, a privately held neuroscience drug discovery company focused on sleep disorders.

5 Mar 2007

Epigenetics to shape stem cell future

Everyone hopes that one day stem cell-based regenerative medicine will help repair diseased tissue. Before then, it may be necessary to decipher the epigenetic signals that give stem cells their unique ability to self-renew and transform them into different cell types.

19 Feb 2007

DNA-encoded antibody libraries

During the past several years, breakthroughs in genomic and proteomic technologies have enabled researchers to more clearly identify the biochemical networks that malfunction when a healthy cell becomes malignant.

12 Feb 2007

New method of screening tumors for cancer-related gene abnormalities

A study led by researchers at Dana-Farber Cancer Institute and Broad Institute of the Massachusetts Institute of Technology and Harvard University provides the first demonstration of a practical method of screening tumors for cancer-related gene abnormalities that might be treated with "targeted" drugs.

11 Feb 2007

Scientists tackle huntingtin protein

McMaster scientists are very close to defining small molecule drugs that should be able to redirect the huntingtin protein from accumulating in the wrong place within brain cells, which could potentially translate to a therapy for Huntington's Disease (HD).

29 Jan 2007