High Throughput Sequencing News and Research

RSS

Researchers underscore role of jumping genes in maintaining genetic diversity

Using high-throughput sequencing to map the locations of a common type of jumping gene within a person's entire genome, researchers at the University of Pennsylvania School of Medicine found extensive variation in these locations among the individuals they studied, further underscoring the role of these errant genes in maintaining genetic diversity.

4 Jun 2010

Life Technologies, DKFZ collaborate to create National High-Throughput Sequencing Center

Life Technologies Corporation and the German Cancer Research Center (Deutsches Krebsforschungszentrum or DKFZ) today announced their collaboration to create the National High-Throughput Sequencing Center. This exclusive partnership will create the largest sequencing facility in Germany and the first national sequencing center in Europe dedicated to systems biology.

3 Jun 2010

RIKEN OSC to purchase CLC bio's high-throughput sequencing analysis solution

Today, RIKEN and CLC bio Japan announced an agreement for the purchase of CLC bio's enterprise platform software by RIKEN Omics Science Center (OSC). CLC bio's high-throughput sequence analysis infrastructure will empower both OSC's scientists and OSC's Genome Network Analysis Service (GeNAS) with a user-friendly and fast workflow to efficiently manage and analyze large quantities of genomics data.

11 May 2010

Inadvertent reprogramming of genes in peripheral nervous system may cause chronic pain

Chronic pain severely limits patients' quality of life and is among the cost drivers in U.S. health care. Patients can suffer pain without an apparent cause and often fail to respond to available treatments. Mayo Clinic researchers and collaborators now report that chronic pain may be caused by the inadvertent reprogramming of more than 2,000 genes in the peripheral nervous system. The research findings appear in the current issue of the journal Genome Research.

7 May 2010

Illumina announces shipment of HiScanSQ system for research needs

Illumina, Inc. today announced shipment of HiScanSQ, the first instrument to integrate microarray analysis and next-generation sequencing in a modular design that can evolve with changing research needs.

From Illumina, Inc. 27 Apr 2010

NextBio announces new Sequence-Centric module for mining high throughput array and sequencing data

NextBio today announced the latest evolution of its innovative life science research platform, adding new capabilities for the integration and mining of high-throughput array and next-generation sequencing data. The new NextBio Sequence-Centric module enables researchers to effectively explore and utilize massive amounts of public and internally generated sequencing data, while allowing organizations to create corporate-wide genomic data platforms to serve the needs of their global research teams.

20 Apr 2010

Finding right balance between high-throughput sequencing and related bioinformatics analysis

Balancing high-throughput sequencing and related bioinformatics analysis between a research group’s internal efforts and specialized service providers can both speed results to difficult biological questions and provide cost-effective access to the latest technology, says Eureka Genomics (EG). The company’s unique capabilities and services and how they can help in “Finding the Right Balance” will be the topic of discussion at a “Java and Jive” session on Wednesday March 17, 8:15 am at the Now-Generation Sequencing conference being held at the Hilton San Diego Resort in San Diego, CA.

17 Mar 2010

Scientists identify specific causative genetic mutation associated with CMT

Scientists using advanced genomic analysis technologies from Life Technologies Corporation have sequenced an individual’s genome and identified the specific causative mutation associated with Charcot-Marie-Tooth Disease (CMT), one of the most common inherited neurological disorders currently affecting 1 in 2,500 individuals in the United States.

11 Mar 2010

Eureka Genomics announces closing of $3.7M private financing round

Eureka Genomics today announced the closing of a $3.7 million private financing round whose participants included private individuals and undisclosed angel investors. The proceeds will further discovery research aimed at identifying novel microorganisms associated with specific cancers and other important diseases, as well as help grow Eureka Genomics’ high-throughput sequencing and bioinformatics service business on a global basis.

11 Mar 2010

Mutations in MeCP2 cause autism spectrum disorder Rett Syndrome

A paper published online today in Molecular Cell proposes that Methyl CpG binding protein 2 (MeCP2) impacts the entire genome in neurons, rather than acting as a regulator of specific genes. Mutations in MeCP2 cause the autism spectrum disorder Rett Syndrome as well as some cases of neuropsychiatric problems including autism, schizophrenia and learning disabilities.

26 Feb 2010

CLC bio, Isilon Systems collaborate to eliminate analysis, storage bottlenecks in high-throughput sequencing workflows

Today, CLC bio, the world's leading bioinformatics solution provider, announced a partnership with Isilon® Systems, Inc. which will help the life science community eliminate some of the toughest workflow bottlenecks when working with high-throughput sequencing data: Analysis and storage.

24 Feb 2010

CLC bio, imaGenes announce collaboration in high-throughput sequencing analyses

Today, the leading provider of High-Throughput Sequencing analysis solutions, CLC bio, announced that they're collaborating with premier German sequencing service provider, imaGenes, to better support the fast growing German market of high-throughput sequencing analyses. imaGenes, will provide all customers receiving Next Generation Sequencing data with a temporary license for CLC Genomics Workbench for assembly and downstream sequence analyses.

3 Dec 2009

Roche's high-throughput sequencing technology used for high-resolution HLA genotyping

A study published this month in the journal Tissue Antigens reports that researchers at Roche Molecular Systems in Pleasanton, CA have used high-throughput sequencing technology from 454 Life Sciences, a Roche Company, to carry out high-resolution human leukocyte antigen (HLA) genotyping in research samples.

27 Oct 2009

GenoLogics and CLC bio to provide end-to-end informatics solution for workflow management

GenoLogics and CLC bio today announced they will provide an end-to-end informatics and analysis solution, optimized for Next Generation Sequencing research that addresses both lab and data management and data analysis all within one integrated system.

19 Oct 2009

First high-throughput analysis of Salmonella Typhi gene

For the first time, researchers are able to look at the need for every gene in a bacterial cell in a single experiment. The new method will transform the study of gene activity and the search for weaknesses in bacterial armouries.

19 Oct 2009

Scientists expand their fleet of genomic next-generation sequencing technology to study about cancer

Scientists from the Baylor College of Medicine Human Genome Sequencing Center (HGSC) are expanding their fleet of advanced genomic next-generation sequencing technology from Applied Biosystems, part of Life Technologies Corporation to accelerate their studies of the genetic underpinnings of cancer and other complex human diseases.

6 Oct 2009

Pharmacogenomics Centre deploys the Isilon IQ to accelerate its next-generation genetic sequencing operations

Isilon® Systems (Nasdaq: ISLN), the proven leader in scale-out NAS, today announced that Pharmacogenomics Centre, a partnership between Genome Quebec and the Montreal Heart Institute focused on enhancing new and existing drug development research programs through the inclusion of genetic information, has deployed Isilon IQ to accelerate its next-generation genetic sequencing operations.

5 Oct 2009

New scalable solutions for targeted re-sequencing studies from febit holding and Life Technologies

febit holding GmbH and Life Technologies Corporation today announced that they have entered into a strategic co-marketing agreement to provide a new, scalable solution for researchers conducting targeted re-sequencing studies. In addition, febit will expand its Genomic Services Facility at Heidelberg by adding several Applied Biosystems SOLiD™ high-throughput sequencing systems and real-time PCR systems.

28 Sep 2009

Raindance Technologies and CLC to develop software for resequencing analysis

RainDance Technologies and CLC bio today announced a partnership to develop specialized software for the analysis of targeted resequencing data generated by workflows incorporating RainDance’s Sequence Enrichment Solution and next generation DNA sequencing platforms.

18 Sep 2009

Discovery of new arenavirus associated with hemorrhagic fever – first identified in nearly four decades

Scientists at Columbia University's Mailman School of Public Health, the South African National Institute for Communicable Diseases of National Health Laboratory Service (NICD-NHLS), the U.S. Centers for Disease Control and Prevention, and Roche's 454 Life Sciences Corporation have discovered the new virus responsible for a highly fatal hemorrhagic fever outbreak in Zambia and South Africa in late 2008.

2 Jun 2009