Hippocampus News and Research

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The hippocampus is a part of the forebrain, located in the medial temporal lobe. It belongs to the limbic system and plays major roles in short term memory and spatial navigation. Humans and other mammals have two hippocampi, one in each side of the brain.

Researchers develop gene therapy reversing memory loss in mice with early-stage Alzheimer's

Alzheimer's disease is the first cause of dementia and affects some 400,000 people in Spain alone. However, no effective cure has yet been found. One of the reasons for this is the lack of knowledge on the cellular mechanisms which cause alterations in nerve transmissions and the loss of memory in the initial stages of the disease.

25 Apr 2014

Physical activity reduces hippocampal atrophy in elders at genetic risk for Alzheimer's disease

A study of older adults at increased risk for Alzheimer's disease shows that moderate physical activity may protect brain health and stave off shrinkage of the hippocampus- the brain region responsible for memory and spatial orientation that is attacked first in Alzheimer's disease.

25 Apr 2014

TSRI scientists identify protein complex that plays critical role in learning and memory formation

Scientists from the Florida campus of The Scripps Research Institute have identified a protein complex that plays a critical but previously unknown role in learning and memory formation.

23 Apr 2014

UT Southwestern researchers identify potential new treatment for depression

Researchers at UT Southwestern Medical Center are making breakthroughs that could benefit people suffering from depression.

23 Apr 2014

Researchers devise new approach to treatment of Alzheimer's disease

A team of researchers from Columbia University Medical Center, Weill Cornell Medical College, and Brandeis University has devised a wholly new approach to the treatment of Alzheimer's disease involving the so-called retromer protein complex. Retromer plays a vital role in neurons, steering amyloid precursor protein (APP) away from a region of the cell where APP is cleaved, creating the potentially toxic byproduct amyloid-beta, which is thought to contribute to the development of Alzheimer's.

21 Apr 2014

Structural changes in hippocampus region improve memory function in children

Our ability to store memories improves during childhood, associated with structural changes in the hippocampus and its connections with prefrontal and parietal cortices.

17 Apr 2014

Scientists create new model of memory that provides complete picture of how memory works

Scientists at the Salk Institute have created a new model of memory that explains how neurons retain select memories a few hours after an event.

17 Apr 2014

Waves in brain make smells stick to memories and inner maps, says study

Waves in your brain make smells stick to your memories and inner maps. When I was a child I used to sit in my grandfather's workshop, playing with wood shavings. Freshly shaven wood has a distinct smell of childhood happiness, and whenever I get a whiff of that scent my brain immediately conjures up images of my grandfather at his working bench, the heat from the fireplace and the dog next to it.

17 Apr 2014

Researchers develop novel tools to learn how astrocytes listen in on neuronal communication

Everything we do - all of our movements, thoughts and feelings - are the result of neurons talking with one another, and recent studies have suggested that some of the conversations might not be all that private.

17 Apr 2014

Genetically modified neural stem cells offer potential treatment for Alzheimer's disease

UC Irvine neurobiologists have found that genetically modified neural stem cells show positive results when transplanted into the brains of mice with the symptoms and pathology of Alzheimer's disease. The pre-clinical trial is published in the journal Stem Cells Research and Therapy, and the approach has been shown to work in two different mouse models.

16 Apr 2014

New lab at the Nencki Institute conducts research on neurodegenerative diseases

The Laboratory of Preclinical Studies of Higher Standard, the newest lab of the Neurobiology Center at the Nencki Institute in Warsaw, Poland, will conduct basic research aimed to explain molecular mechanisms responsible for neurodegenerative diseases.

9 Apr 2014

DNA modifications in blood are directly related to changes in brain tissues, say researchers

Johns Hopkins researchers say they have confirmed suspicions that DNA modifications found in the blood of mice exposed to high levels of stress hormone — and showing signs of anxiety — are directly related to changes found in their brain tissues.

9 Apr 2014

Caffeine has positive effect on tau deposits in Alzheimer's disease

As part of a German-French research project, a team led by Dr. Christa E. Müller from the University of Bonn and Dr. David Blum from the University of Lille was able to demonstrate for the first time that caffeine has a positive effect on tau deposits in Alzheimer's disease.

7 Apr 2014

Neuroinflammation levels higher in patients with chronic fatigue syndrome

Researchers at the RIKEN Center for Life Science Technologies, in collaboration with Osaka City University and Kansai University of Welfare Sciences, have used functional PET imaging to show that levels of neuroinflammation, or inflammation of the nervous system, are higher in patients with chronic fatigue syndrome than in healthy people.

4 Apr 2014

Study reveals role of dopamine in hippocampus region of brain

Bruno Giros, PhD, a researcher at the Douglas Mental Health University Institute and a professor in the Department of Psychiatry at McGill University, has demonstrated, for the first time, the role that dopamine plays in a region of the brain called the hippocampus.

4 Apr 2014

Aspartic acid in hippocampus may be biomarker for predicting occurrence of cognitive dysfunction

Postoperative cognitive dysfunction is the deterioration of cognitive performance after anesthesia and surgery, and manifests as impairments in short-term memory, concentration, language comprehension, and social integration skills.

31 Mar 2014

Early life chronic stress may cause anxiety in adulthood, says study

In recent years, behavioral neuroscientists have debated the meaning and significance of a plethora of independently conducted experiments seeking to establish the impact of chronic, early-life stress upon behavior - both at the time that stress is experienced, and upon the same individuals later in life, during adulthood.

28 Mar 2014

New subcellular mechanism identified for fast transmission in basket cells of the brain

In his third major research paper since December 2013, IST Austria Professor Peter Jonas together with his collaborator, postdoc Hua Hu, identifies a new subcellular mechanism for reliable, fast transmission in the so-called basket cells of the brain.

25 Mar 2014

People who develop diabetes in middle age are more likely to have brain cell loss in old age

People who develop diabetes and high blood pressure in middle age are more likely to have brain cell loss and other damage to the brain, as well as problems with memory and thinking skills, than people who never have diabetes or high blood pressure or who develop it in old age, according to a new study published in the March 19, 2014, online issue of Neurology®, the medical journal of the American Academy of Neurology.

20 Mar 2014

Biological basis for visual hallucinations identified

Visual hallucinations in patients with schizophrenia may be caused by hyperconnectivity in a specific area of the brain, say researchers.

19 Mar 2014

Hippocampus News and Research

Further Reading

Researchers develop gene therapy reversing memory loss in mice with early-stage Alzheimer's

Physical activity reduces hippocampal atrophy in elders at genetic risk for Alzheimer's disease

TSRI scientists identify protein complex that plays critical role in learning and memory formation

UT Southwestern researchers identify potential new treatment for depression

Researchers devise new approach to treatment of Alzheimer's disease

Structural changes in hippocampus region improve memory function in children

Scientists create new model of memory that provides complete picture of how memory works

Waves in brain make smells stick to memories and inner maps, says study

Researchers develop novel tools to learn how astrocytes listen in on neuronal communication

Genetically modified neural stem cells offer potential treatment for Alzheimer's disease

New lab at the Nencki Institute conducts research on neurodegenerative diseases

DNA modifications in blood are directly related to changes in brain tissues, say researchers

Caffeine has positive effect on tau deposits in Alzheimer's disease

Neuroinflammation levels higher in patients with chronic fatigue syndrome

Study reveals role of dopamine in hippocampus region of brain

Aspartic acid in hippocampus may be biomarker for predicting occurrence of cognitive dysfunction

Early life chronic stress may cause anxiety in adulthood, says study

New subcellular mechanism identified for fast transmission in basket cells of the brain

People who develop diabetes in middle age are more likely to have brain cell loss in old age

Biological basis for visual hallucinations identified

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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