Hippocampus News and Research

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The hippocampus is a part of the forebrain, located in the medial temporal lobe. It belongs to the limbic system and plays major roles in short term memory and spatial navigation. Humans and other mammals have two hippocampi, one in each side of the brain.

Ion channel acts as powerful ‘brake’ after epileptic seizures

Given that epilepsy impacts more than 2 million Americans, there is a pressing need for new therapies to prevent this disabling neurological disorder. New findings from the neuroscience laboratory of Mark S. Shapiro, Ph.D., at The University of Texas Health Science Center at San Antonio, published Dec. 20 in the high-impact scientific journal, Neuron, may provide hope.

19 Dec 2012

University of North Carolina awards 13th Perl prize to two NTNU-Trondheim scientists

The University of North Carolina at Chapel Hill has awarded the 13th Perl-UNC Neuroscience prize jointly to Edvard and May-Britt Moser at the Norwegian University of Science and Technology (NTNU-Trondheim) in Trondheim, Norway.

17 Dec 2012

Relatives of schizophrenia patients show cortical thinning

Patients with schizophrenia and their unaffected relatives show significant cortical thinning compared with mentally healthy individuals without such a family history, researchers report.

13 Dec 2012

First U.S. patient treated with deep brain stimulation for Alzheimer's at Johns Hopkins

Researchers at Johns Hopkins Medicine in November surgically implanted a pacemaker-like device into the brain of a patient in the early stages of Alzheimer's disease, the first such operation in the United States. The device, which provides deep brain stimulation and has been used in thousands of people with Parkinson's disease, is seen as a possible means of boosting memory and reversing cognitive decline.

6 Dec 2012

UI researchers develop neonatal piglet model to study micronutrient deficiencies

University of Illinois researchers have developed a model that uses neonatal piglets for studying infant brain development and its effect on learning and memory. To determine if the model is nutrient-sensitive, they have done some research on the effects of iron-deficient diets.

4 Dec 2012

Long-term hippocampal DBS effectively reduces seizures in experimental models

The results of the first reported study of deep brain stimulation (DBS) in an animal model for temporal lobe epilepsy (TLE) presented today at the American Epilepsy Society (AES) 66th Annual Meeting suggests that DBS may have potential as therapy for this common and often difficult to treat form of epilepsy.

2 Dec 2012

LP-211 compound shows promise against Fragile X syndrome

A potential new therapeutic strategy for treating Fragile X syndrome is detailed in a new report appearing in the current issue of Biological Psychiatry, from researchers led by Dr. Lucia Ciranna at University of Catania in Italy.

29 Nov 2012

Microglia might play a key role in protecting brain from Alzheimer's

A new experimental study carried out in mice shows that microglia, immune cells of the brain, might play a key role in protecting the brain from Alzheimer's disease (AD).

29 Nov 2012

Creative art therapy combined with MBSR program shows promise for women with breast cancer

Cancer and stress go hand-in-hand, and high stress levels can lead to poorer health outcomes in cancer patients. The Jefferson-Myrna Brind Center of Integrative Medicine combined creative art therapy with a Mindfulness-based Stress Reduction (MBSR) program for women with breast cancer and showed changes in brain activity associated with lower stress and anxiety after the eight-week program.

29 Nov 2012

French National Center for Scientific Research scientist wins American Epilepsy Society award

Richard Miles, Ph.D., Research Director, French National Center for Scientific Research, and Group Leader, Cortex and Epilepsy, Institute for the Brain and Spinal Cord, Centre Hospitalier Universtaire Pitie-Salpetriere, Paris, has been named recipient of the prestigious 2012 Epilepsy Research Recognition Award for Basic Science conferred by the American Epilepsy Society (AES).

28 Nov 2012

Active lifestyle helps preserve brain structure and could reduce burden of dementia, Alzheimer's

An active lifestyle helps preserve gray matter in the brains of older adults and could reduce the burden of dementia and Alzheimer's disease (AD), according to a study presented today at the annual meeting of the Radiological Society of North America (RSNA).

26 Nov 2012

Max Planck Institute develops neural event-triggered functional magnetic resonance imaging

While in deep dreamless sleep, our hippocampus sends messages to our cortex and changes its plasticity, possibly transferring recently acquired knowledge to long-term memory. But how exactly is this done? Scientists from the Max Planck Institute for Biological Cybernetics have now developed a novel multimodal methodology called "neural event-triggered functional magnetic resonance imaging" (NET-fMRI) and presented the very first results obtained using it in experiments with both anesthetized and awake, behaving monkeys.

22 Nov 2012

Study: 2-PMPA improves cognition in mice with MS

Johns Hopkins researchers report the successful use of a form of MRI to identify what appears to be a key biochemical marker for cognitive impairment in the brains of people with multiple sclerosis (MS). In follow-up experiments on mice with a rodent form of MS, researchers were able to use an experimental compound to manipulate that same marker and dramatically improve learning and memory.

21 Nov 2012

Researchers discover new gene for susceptibility to Alzheimer's disease

A large-scale international study involving French researchers from the Inserm-Institut Pasteur Lille-Universit- Lille Nord de France "Public health and molecular epidemiology of ageing-related diseases" joint research unit led by Philippe Amouyel, has just discovered a gene for susceptibility to a rare disease that causes susceptibility to a common one, Alzheimer's disease, providing evidence of the heterogeneous aetiology of Alzheimer's disease.

20 Nov 2012

New way to stimulate transplanted human stem cell-derived neurons into a rodent hippocampus

Researchers and patients look forward to the day when stem cells might be used to replace dying brain cells in Alzheimer's disease and other neurodegenerative conditions. Scientists are currently able to make neurons and other brain cells from stem cells, but getting these neurons to properly function when transplanted to the host has proven to be more difficult.

17 Nov 2012

Researchers analyze Brazilian mediums' cerebral blood flow during practice of psychography

Researchers at Thomas Jefferson University and the University of Sao Paulo in Brazil analyzed the cerebral blood flow (CBF) of Brazilian mediums during the practice of psychography, described as a form of writing whereby a deceased person or spirit is believed to write through the medium's hand.

17 Nov 2012

Maternal vitamin C deficiency can have serious consequences for foetal brain

Maternal vitamin C deficiency during pregnancy can have serious consequences for the foetal brain. And once brain damage has occurred, it cannot be reversed by vitamin C supplements after birth. This is shown through new research at the University of Copenhagen just published in the scientific journal PLOS ONE.

16 Nov 2012

Irregular sleep patterns may trigger schizophrenia symptoms

Neuroscientists studying the link between poor sleep and schizophrenia have found that irregular sleep patterns and desynchronised brain activity during sleep could trigger some of the disease's symptoms. The findings, published in the journal Neuron, suggest that these prolonged disturbances might be a cause and not just a consequence of the disorder's debilitating effects.

15 Nov 2012

MRI, EEG may predict children’s epilepsy risk after long febrile seizures

Children who have prolonged febrile seizures are at increased risk for magnetic resonance imaging observed hippocampal injury and abnormal hippocampal and temporal development, show results from the Consequences of Prolonged Febrile Seizures in Childhood study.

13 Nov 2012

Early clues regarding progression of Alzheimer's disease found in brain's metabolism

When it comes to Alzheimer's disease, scientists usually - and understandably - look to the brain as their first center of attention. Now researchers at Tel Aviv University say that early clues regarding the progression of the disease can be found in the brain's metabolism.

8 Nov 2012

Hippocampus News and Research

Further Reading

Ion channel acts as powerful ‘brake’ after epileptic seizures

University of North Carolina awards 13th Perl prize to two NTNU-Trondheim scientists

Relatives of schizophrenia patients show cortical thinning

First U.S. patient treated with deep brain stimulation for Alzheimer's at Johns Hopkins

UI researchers develop neonatal piglet model to study micronutrient deficiencies

Long-term hippocampal DBS effectively reduces seizures in experimental models

LP-211 compound shows promise against Fragile X syndrome

Microglia might play a key role in protecting brain from Alzheimer's

Creative art therapy combined with MBSR program shows promise for women with breast cancer

French National Center for Scientific Research scientist wins American Epilepsy Society award

Active lifestyle helps preserve brain structure and could reduce burden of dementia, Alzheimer's

Max Planck Institute develops neural event-triggered functional magnetic resonance imaging

Study: 2-PMPA improves cognition in mice with MS

Researchers discover new gene for susceptibility to Alzheimer's disease

New way to stimulate transplanted human stem cell-derived neurons into a rodent hippocampus

Researchers analyze Brazilian mediums' cerebral blood flow during practice of psychography

Maternal vitamin C deficiency can have serious consequences for foetal brain

Irregular sleep patterns may trigger schizophrenia symptoms

MRI, EEG may predict children’s epilepsy risk after long febrile seizures

Early clues regarding progression of Alzheimer's disease found in brain's metabolism

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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