Histamine News and Research

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Histamine is a biogenic amine chemical involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.

U.K. doctors test lipid ibuprofen as COVID-19 treatment

The non-steroidal anti-inflammatory drug (NSAID) Ibuprofen is being tested as a potential treatment for the coronavirus disease (COVID-19). Doctors in the United Kingdom rolled out a clinical trial of the everyday painkiller to see if it reduces respiratory failure in patients experiencing severe COVID-19 disease.

4 Jun 2020

New drug can prevent life-threatening anaphylaxis, shows study

For someone with a food or drug allergy, the risk of life-threatening anaphylactic shock lurks around every corner. A new Northwestern Medicine study shows there might be a pill that can be taken proactively to prevent mild to life-threatening anaphylaxis, no matter the cause.

3 Jun 2020

Researchers uncover novel neurotransmitter system in the brain

Neurotransmitters are chemicals that transmit signals between neurons or from neurons to other cells. They interact with specific receptors found in the brain of humans and animals, controlling a variety of biological processes, e.g. fear, anger, pleasure, memory, energy, appetite and sleep.

5 Mar 2020

Scientific breakthrough provides insights into basic mechanisms of allergic reactions

An international research team has been able to describe the overall structure of the antibody type IgE, which is the key molecule in allergic diseases.

24 Feb 2020

Researchers succeed in creating complex pattern of hives

Hives afflict 1 in 5 people, but the exact mechanisms behind the itchy red rashes are not well known. The research team studied the patterns of hives in patients and reproduced the hive patterns using a mathematical model called a reaction-diffusion model, a common prototype for understanding how patterns develop. The researchers' model is a single equation type which had never before been used to generate complex patterns.

28 Jan 2020

Study identifies several drugs with potential to prevent suicide attempts

A review of 922 prescription medications taken by almost 150 million people over an 11-year period shows that just 10 of these drugs were associated with an increased rate of suicide attempts.

5 Nov 2019

FDA warns about Ranitidine containing known carcinogen NDMA

The United States Food and Drug Administration have issued a warning regarding some substances present in a brand of Ranitidine that could be carcinogenic. In their first warning issued on the 13th of this month, the FDA warns that one of the brands of Ranitidine, Zantac is said to contain a nitrosamine impurity called N-nitrosodimethylamine (NDMA) at low levels. NDMA is a known carcinogen, the report reads based on lab data and is also found in the environment, food and water the report adds.

26 Sep 2019

Unraveling the secret itch pathway

Itching is among the most persistent of skin sensations, requiring an immediate response. However, scientists say it is a protective sensation that stimulates the individual to eliminate parasites and other irritating substances from the skin.

23 Aug 2019

Researchers synthesize artificial cells to detect histamine

Baking a cake from scratch is a task deemed difficult for many. Constructing an artificial cell-like system from scratch, well that's another story.

3 Jul 2019

$Early exposure to antacids could put infants at risk for bone fractures during childhood$

Early exposure to antacids could put infants at risk for bone fractures during childhood

Infants who are given antacids in their first year of life are more likely to fracture a bone later as a child, according to a new study published June 7 in Pediatrics.

11 Jun 2019

Young eczema sufferers infected with common skin bacterium are at higher risk of food allergy

In a new study published today in the Journal of Allergy and Clinical Immunology, scientists from King's College London have found that young children with severe eczema infected with Staphylococcus aureus bacterium, are at a higher risk of developing a food allergy.

31 May 2019

Common acid reflux drugs tied to elevated risk for kidney disease

Proton pump inhibitors, which include well-known brand names Prilosec, Nexium and Prevacid, are among the most commonly prescribed medications in the world. Approximately 10 percent of adults in the United States take these drugs for frequent heartburn, acid reflux and gastroesophageal reflux disease.

19 Feb 2019

Researchers reveal brain mechanism that drives itch-evoked scratching behavior

It's a maddening cycle that has affected us all: it starts with an itch that triggers scratching, but scratching only makes the itchiness worse.

14 Dec 2018

Study identifies new potential target for treating major common diseases

There is a large, untapped potential for developing drugs against cancer, fibrosis and cardiovascular diseases by targeting a family of receptors known as Frizzleds, researchers at Karolinska Institutet in Sweden believe. In a new study published in Science Signaling, they identify how these receptors are activated in the cell membrane and the processes that are then triggered within the cell.

4 Dec 2018