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Omicron variant may strike double vaccinated

Largely, scientists are skeptical that the Omicron variant can infect vaccinated individuals. However, a new study published on the medRxiv* preprint server has conducted neutralization assays using an Omicron isolate obtained from patients residing in the United Kingdom.

13 Dec 2021

Characteristics of vaccine breakthroughs in fully vaccinated individuals in France with delta variant

In a recent observational study, scientists have described the characteristics of VBIs in fully vaccinated individuals in France.

13 Dec 2021

SARS-CoV-2 omicron variant may evade host immune responses

A recent study has demonstrated that the omicron variant of severe acute respiratory syndrome coronavirus 2 has a higher ability to evade antibody-mediated neutralization than other variants of concern.

13 Dec 2021

Equilibrium simulation of SARS-CoV-2 spike protein highlights its global conformational characteristics

A team of researchers set out to build a full-length, membrane-embedded spike to study its conformational dynamics at the atomic level using molecular dynamics simulations to understand better how this important component of the virus machinery works.

8 Dec 2021

Homologous mRNA and heterologous vaccines elicit high immune responses

New study findings show that homologous mRNA or heterologous vaccination induces the highest immune responses due to high RBD- and S1-specific antibodies.

7 Dec 2021

Immune response of Pfizer vaccinees who received Moderna or Pfizer booster

A new preprint discusses the immune boost resulting from homologous or heterologous booster doses in individuals fully vaccinated with two doses of the Pfizer vaccine.

7 Dec 2021

SARS-CoV-2 S2 immunization as a pan-coronavirus vaccine approach

A new mouse model suggests that prior HCoV-OC43 S immunity primes neutralising antibody responses to otherwise subimmunogenic SARS-CoV-2 S exposure as well as promotes S2-targeting antibody responses.

6 Dec 2021

Study shows COVID booster shots work

A new study investigates uses seven different COVID-19 vaccines as the third dose to boost immunity in vulnerable patients.

6 Dec 2021

Preclinical data shows enhanced T-cell responses & neutralization of SARS-CoV-2 variants with ImmunityBio heterologous vaccination

A new study supports the hypothesis that heterologous vaccination can provide an increased immune response against virus infection, supporting several other studies that have indicated similar events.

5 Dec 2021

Do we need COVID-19 vaccine boosters?

An article published recently in the Journal of Virology explored the science behind COVID-19 vaccine boosters.

29 Nov 2021

Vaccines and boosters remain strong against current SARS-CoV-2 variants

In a recent study published in the Lancet Microbe journal, Australian researchers studied whether in-vitro neutralization titers could predict vaccine protection from SARS-CoV-2 variants.

17 Nov 2021

Impact of COVID-19 vaccination in the Norwegian population

Researchers quantified the general VE achieved in the population of Norway, with the realized mixture of vaccine types, current population characteristics, and epidemic trajectory and directly estimated VE across vaccine types and age groups.

16 Nov 2021

Deficient spike-specific T cell responses and inability to neutralize SARS-CoV-2 variants 12 month post-infection

Researchers conducted a comprehensive, longitudinal, long-term immune study, including functional assays to assess immune fitness against antigenically different VoC. The study is currently available on the preprint server medRxiv* while awaiting peer review.

15 Nov 2021

SARS-CoV-2 self-amplifying mRNA vaccine demonstrates cellular and humoral immune responses

Researchers from the US recently reported the preclinical development of a self-amplifying mRNA (SAM) vaccine that encodes a prefusion-stabilized SARS-CoV-2 spike glycoprotein.

12 Nov 2021

Study points to a new, effective treatment option for patients with mesothelioma

Combining the immunotherapy agent durvalumab with the chemotherapy agents pemetrexed and cisplatin or carboplatin may provide a new treatment option for patients who have inoperable pleural mesothelioma, a cancer of the tissues lining the lungs, according to a phase II clinical trial led by researchers at the Johns Hopkins Kimmel Cancer Center and the Bloomberg~Kimmel Institute for Cancer Immunotherapy.

8 Nov 2021

Study compares efficacy of BNT162b2 and CoronaVac as the booster dose for COVID-19 vaccination

A recent study reports the immunogenicity and safety of BNT162b2 and CoronaVac as the third dose in CoronaVac-immunized adults.

8 Nov 2021

Cuba reports 92.4 percent efficacy for 3 dose SOBERANA 02 COVID-19 vaccine

A new study describes the results of the safety and efficacy phase trials of a new COVID-19 vaccine from Cuba.

4 Nov 2021

Cross-reactive immunity against coronaviruses

Researchers review the heterologous immunity to coronaviruses and the extent of immune cross-reactivity against SARS-CoV-2.

3 Nov 2021

Pre-clinical follow-up study boosting with original formulation and next generation INO-4802 SARS-CoV-2 vaccine candidate

Researchers describe the antibody-inducing effects of DNA-based synthetic vaccines INO-4800 and INO-4802 against SARS-CoV-2 in non-human primates.

3 Nov 2021

Humoral immunity following heterologous and homologous COVID-19 vaccination regimens

Researchers sought to analyze immune responses after homologous vaccinations or after heterologous Vector/mRNA vaccinations, with respect to anti-COVID-19 immune responses and the development of autoantibodies.

3 Nov 2021

Homologous News and Research

Omicron variant may strike double vaccinated

Characteristics of vaccine breakthroughs in fully vaccinated individuals in France with delta variant

SARS-CoV-2 omicron variant may evade host immune responses

Equilibrium simulation of SARS-CoV-2 spike protein highlights its global conformational characteristics

Homologous mRNA and heterologous vaccines elicit high immune responses

Immune response of Pfizer vaccinees who received Moderna or Pfizer booster

SARS-CoV-2 S2 immunization as a pan-coronavirus vaccine approach

Study shows COVID booster shots work

Preclinical data shows enhanced T-cell responses & neutralization of SARS-CoV-2 variants with ImmunityBio heterologous vaccination

Do we need COVID-19 vaccine boosters?

Vaccines and boosters remain strong against current SARS-CoV-2 variants

Impact of COVID-19 vaccination in the Norwegian population

Deficient spike-specific T cell responses and inability to neutralize SARS-CoV-2 variants 12 month post-infection

SARS-CoV-2 self-amplifying mRNA vaccine demonstrates cellular and humoral immune responses

Study points to a new, effective treatment option for patients with mesothelioma

Study compares efficacy of BNT162b2 and CoronaVac as the booster dose for COVID-19 vaccination

Cuba reports 92.4 percent efficacy for 3 dose SOBERANA 02 COVID-19 vaccine

Cross-reactive immunity against coronaviruses

Pre-clinical follow-up study boosting with original formulation and next generation INO-4802 SARS-CoV-2 vaccine candidate

Humoral immunity following heterologous and homologous COVID-19 vaccination regimens

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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