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White-tailed deer susceptible to SARS-CoV-2, finds study

White-tailed deer have been observed to be susceptible to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). They can also transmit the virus both through direct and indirect contact to one another, researchers find. The research paper is available to be read online in the Journal of Virology.

15 Mar 2021

Researchers present fragment-based computational design of antibodies that target structured epitopes

A new study describes a novel fragment-based method to design antibody complementarity determining region (CDR) loops.

8 Mar 2021

Apoptosis is an important mediator of pathogenesis in animal coronavirus infection

A new paper in the journal Life presents an early review of the viral factors involved in initiating and effecting apoptosis within infected cells.

8 Mar 2021

Influenza A virus defective interfering particles against SARS-CoV-2

In the search for a broadly acting pan-specific antiviral, an interdisciplinary team from Germany tested the previously proposed (for antiviral treatment against Influenza A infections) - Influenza A virus (IAV) defective interfering particles (DIPs). The research is published online on the bioRxiv preprint server.

23 Feb 2021

SARS-CoV-2 DNA vaccine tested in animal model

A team of experts has tested the immune responses elicited by mucosal homologous plasmid and a heterologous immunization strategy using a plasmid vaccine and a Modified Vaccinia Ankara (MVA) expressing SARS-CoV-2 spike (S) and nucleocapsid (N) antigens.

21 Feb 2021

Where might future novel coronaviruses come from?

The researchers predicted many more associations between coronaviruses and host species than have been observed to date. They also predicted 30 times more potential recombination hosts of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

17 Feb 2021

Scientists examine DNA repair pathways and their impact on cancer evolution

DNA repair pathways exist to correct molecular damage caused by internal and external factors. However, any damage to these pathways can result in the creation of tumors and specific types of cancers.

17 Feb 2021

New mouse model of SARS-CoV-2 infection reflects features of human infection

Now, a new preprint research paper posted to the bioRxiv server reports the development of a modified mouse model that allows productive SARS-CoV-2 infection of the mouse lungs, as well as the exploration of type I and III interferon responses in this condition.

14 Feb 2021

Scientists demonstrate how glue points and sequence alignment information can flag residue SARS-CoV-2 variants

Researchers in the U.S. have demonstrated how dominant energetic landscape mappings or glue points, along with sequence alignment information can potentially identify key residue mutations and spike protein deletions tied with emerging variants.

12 Feb 2021

A known tumor suppressor gene plays role in stress protection of adult progenitor cells

Adult progenitor cells are present in the Drosophila fly as early as its larvae stage. These cells are the only ones that are maintained throughout development and they are responsible for giving rise to adult tissues and organs.

9 Feb 2021

Alpaca nanobodies neutralize SARS-CoV-2 in vitro

A new preprint research paper posted to the bioRxiv server reports the development of highly effective neutralizing nanobodies targeting the viral receptor-binding domain (RBD), thus disrupting its engagement with the host cell angiotensin-converting enzyme 2 (ACE2) receptor.

4 Feb 2021

Evolutionary history reveals the function of fish and human bitter receptors

To evaluate the chemical composition of food from a physiological point of view, it is important to know the functions of the receptors that interact with food ingredients.

2 Feb 2021

Inhaled single dose vaccine creates antibodies and prevents infection in rhesus macaques

Now, a new preprint research paper describes a chimpanzee adenovirus-vectored vaccine that, when administered intranasally in rhesus macaques, led to a robust immune response and demonstrated protection against infection by the virus that causes COVID-19, namely, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The preprint is published on the bioRxiv server.

1 Feb 2021

India's Covaxin vaccine likely effective against UK SARS-CoV-2 variant: Study

A new preprint research paper, posted to the preprint server bioRxiv, presents data indicating that the Indian-made Covaxin vaccine candidate successfully neutralizes this variant, preventing infection when challenged by it.

1 Feb 2021

Lower CD4 T cell reactivity to seasonal coronaviruses found in healthcare workers with COVID-19

A new study by US-based researchers describes the results of a study on the immune response among healthcare workers, in particular, their T cell responses predating the pandemic.

19 Jan 2021

Study supports continuing phase 3 trials of Ad26.COV2.S SARS-CoV-2 vaccine

An international team of researchers has provided further evidence to confirm the immunogenicity and efficacy of a recombinant adenovirus vaccine currently being tested in phase 3 trials for its ability to protect against infection with severe acute respiratory coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

11 Jan 2021

Homologous News and Research

White-tailed deer susceptible to SARS-CoV-2, finds study

Researchers present fragment-based computational design of antibodies that target structured epitopes

Apoptosis is an important mediator of pathogenesis in animal coronavirus infection

Influenza A virus defective interfering particles against SARS-CoV-2

SARS-CoV-2 DNA vaccine tested in animal model

Where might future novel coronaviruses come from?

Scientists examine DNA repair pathways and their impact on cancer evolution

New mouse model of SARS-CoV-2 infection reflects features of human infection

Scientists demonstrate how glue points and sequence alignment information can flag residue SARS-CoV-2 variants

A known tumor suppressor gene plays role in stress protection of adult progenitor cells

Alpaca nanobodies neutralize SARS-CoV-2 in vitro

Evolutionary history reveals the function of fish and human bitter receptors

Inhaled single dose vaccine creates antibodies and prevents infection in rhesus macaques

India's Covaxin vaccine likely effective against UK SARS-CoV-2 variant: Study

Lower CD4 T cell reactivity to seasonal coronaviruses found in healthcare workers with COVID-19

Study supports continuing phase 3 trials of Ad26.COV2.S SARS-CoV-2 vaccine

Modified Vaccinia Ankara model vaccine prevents COVID-19 in transgenic mice study

Discovery about DNA repair enzyme could lead to new treatments for certain cancers

Prior T cell immunity to SARS-CoV-2 unlikely to be the result of seasonal coronavirus infection

Repair protein may prevent damage to healthy cells during cancer therapy

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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