Hormonal Therapy News and Research

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Hormonal Therapy is treatment that adds, blocks, or removes hormones. For certain conditions (such as diabetes or menopause), hormones are given to adjust low hormone levels. To slow or stop the growth of certain cancers (such as prostate and breast cancer), synthetic hormones or other drugs may be given to block the body’s natural hormones. Sometimes surgery is needed to remove the gland that makes a certain hormone. Also called endocrine therapy, hormone therapy, and hormone treatment.

Combined chemohormonal therapy for locally advanced prostate cancer offers extended control of PSA levels

For patients with locally advanced prostate cancer, combined treatment with chemotherapy and hormonal therapy offers extended control of prostate-specific antigen (PSA) levels, compared to hormonal therapy alone, reports a study in the April issue of The Journal of Urology, an Official Journal of the American Urological Association.

17 Apr 2024

Study shows safety of avoiding extensive lymph node removal in breast cancer patients

It is possible to leave most of the lymph nodes in the armpit, even if one or two of them have metastases larger than two millimeters? This is shown in a trial enrolling women from five countries, led by researchers at Karolinska Institutet and published in the New England Journal of Medicine.

4 Apr 2024

Cryoablation could be a new treatment path for breast cancer patients with large tumors

A minimally invasive technique that uses ice to freeze and destroy small, cancerous tumors has now been proven effective for breast cancer patients with large tumors, providing a new treatment path for those who are not candidates for surgery, according to new research to be presented at the Society of Interventional Radiology Annual Scientific Meeting in Salt Lake City.

20 Mar 2024

Association of estrogen-containing menopause hormonal therapy with COVID-19 mortality

Researchers evaluated coronavirus disease 2019 (COVID-19)-related mortality among perimenopausal women.

29 Feb 2024

New study unlocks hope for immunotherapy in metastatic prostate cancer

Immunotherapy has been disappointing as a prostate cancer treatment, but a new Columbia study suggests that the powerful treatments have potential when the disease starts to spread.

12 Dec 2023

Are there racial and ethnic disparities in the use of novel hormonal therapy agents in men with advanced prostate cancer?

Researchers assessed ethnic and racial differences in novel hormonal therapy (NHT) use among advanced prostate cancer (PCa) patients.

6 Dec 2023

Study finds racial disparity in the utilization of crucial prostate cancer therapy

A new study led by investigators at the UCLA Health Jonsson Comprehensive Cancer Center found Black men diagnosed with more advanced stages of prostate cancer are significantly less likely to be prescribed novel hormone therapy than other racial and ethnic groups – including white or Latino men – despite the therapy being proven to effectively control the growth of prostate tumors and extend the lives of men with the disease.

1 Dec 2023

Dietary saturated fats may influence male hormone levels, new study suggests

Study finds no independent link between dietary fats and androgen levels in middle-aged men; however, replacing protein calories with saturated fatty acids may raise serological androgen levels, suggesting diet's potential impact on male hormonal health.

23 Nov 2023

Managing menopause: The 2023 toolkit for healthcare practitioners

The authors of the revised 2023 Toolkit extracted key recommendations from professional guidelines and positions as well as consensus statements on menopause and related conditions that have emerged since 2014.

1 Nov 2023

Can exercise, intermittent fasting help patients better tolerate side effects from breast cancer treatment?

Can lifestyle interventions such as exercise and intermittent fasting help patients with advanced breast cancer better tolerate side effects from treatment?

17 Oct 2023

Shorter course of radiation therapy just as effective for intermediate risk prostate cancer, study shows

People with intermediate risk, localized prostate cancer can be treated as effectively using fewer and higher doses of radiation therapy delivered over five treatment sessions as they can with lower doses delivered over several weeks, a new phase III randomized trial suggests.

3 Oct 2023

New treatment approach effectively treats the most aggressive forms of prostate cancer

Researchers at the University of Chicago Medicine Comprehensive Cancer Center established "proof-of-concept" for a new treatment approach that was able to effectively treat the most aggressive forms of prostate cancer. The treatment showed complete tumor control and long-lasting survival without side effects in a mouse model of advanced prostate cancer.

19 Sep 2023

PSMA PET/CT can diagnose advanced prostate cancer in elderly patients without biopsy

In elderly patients with suspected prostate cancer, PSMA PET/CT can diagnose advanced disease and aid in therapy selection without the need for a biopsy.

14 Aug 2023

Transgender adolescents rarely chose to discontinue gender-affirming hormone therapy, finds study

A three-year-long retrospective cohort study of a single Atlanta hospital's patient population found transgender and gender-diverse teenagers rarely chose to discontinue gender-affirming hormone therapy, according to a study being presented Sunday at ENDO 2023, the Endocrine Society's annual meeting in Chicago, Ill.

18 Jun 2023

Does recurrent bacterial vaginosis impact quality of life?

A recent BMC Women's Health study performed a survey to understand how bacterial vaginosis affects women’s quality of life and what treatment they underwent.

22 Mar 2023

Overview of the causes, diagnosis and management of endometriosis

Endometriosis is a painful, complex condition affecting about 1 in 10 women of reproductive age, but it is poorly understood.

14 Mar 2023

Growing use of immunotherapy linked to increase in Medicare spending for outpatient terminal cancer care

A new study finds that recent increases in Medicare spending on outpatient cancer care at the end of patients' lives were driven almost entirely by a type of treatment given to fewer than 1 in 5 patients.

27 Feb 2023

Hormonal therapy may aid in reducing progression of early-stage prostate cancer during active surveillance

For men with early-stage prostate cancer being managed by active surveillance, adding the hormonal agent apalutamide may lower the rate of positive biopsies during follow-up, suggests a preliminary clinical trial in The Journal of Urology, an Official Journal of the American Urological Association.

11 Jan 2023

Detailed molecular profile of endometriosis can lead to improved care for millions of women

Investigators at Cedars-Sinai have created a unique and detailed molecular profile of endometriosis to help improve therapeutic options for the millions of women suffering from the disease.

9 Jan 2023

Study seeks to look for a better treatment for endometriosis

Up to 15% of women of reproductive age in the United States suffer from endometriosis, a condition characterized by pelvic pain, menstrual cramps and infertility.

14 Dec 2022