Hormonal Therapy News and Research

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Hormonal Therapy is treatment that adds, blocks, or removes hormones. For certain conditions (such as diabetes or menopause), hormones are given to adjust low hormone levels. To slow or stop the growth of certain cancers (such as prostate and breast cancer), synthetic hormones or other drugs may be given to block the body’s natural hormones. Sometimes surgery is needed to remove the gland that makes a certain hormone. Also called endocrine therapy, hormone therapy, and hormone treatment.

Targeted therapy slows disease progression and improves survival for prostate cancer

A new PARP-inhibitor has been shown to significantly delayed cancer progression among patients with prostate cancer who had cancer cells with faulty DNA repair genes.

2 Oct 2019

Adding targeted therapy drug to standard treatment benefits aggressive breast cancer patients

A study led by UCLA researchers found that adding ribociclib, a targeted therapy drug, to standard hormone therapy has been shown to significantly improve overall survival in postmenopausal women with advanced hormone-receptor positive/HER2- breast cancer, one of the most common forms of the disease.

29 Sep 2019

Breast cancer cells can go into sleep mode and relapse in the future

Breast cancer is one of the most aggressive types of cancers in the world. It is the commonest cause of cancer death in women worldwide, and it represented about 12 percent of all new cancer cases in 2012. Current predictions and statistics suggest that both worldwide incidence of breast cancer and related mortality are on the rise. Globally, breast cancer now represents one in four of all cancers in women.

3 Sep 2019

Electromagnetic fields may prevent spread of breast cancer cells, study finds

Electromagnetic fields might help prevent some breast cancers from spreading to other parts of the body, new research has found.

8 Aug 2019

AI-enabled device detects if targeted chemotherapy is working

A new portable device that utilizes artificial intelligence (AI) and biosensors can rapidly detect if cancer cells thrive after chemotherapy treatment.

17 Jul 2019

Sleep quality and fatigue among women with premature ovarian insufficiency

There have been studies and anecdotal reports about worsening of sleep quality and increasing fatigue among women who are near menopause or have reached menopause.

16 Jul 2019

Botulinum toxin may offer relief from chronic pelvic pain in women with endometriosis

Pelvic pain associated with endometriosis often becomes chronic and can persist (or recur) following surgical and hormonal interventions.

11 Jul 2019

Targeted therapy plus hormone therapy improves survival in premenopausal patients with advanced HR+ breast cancer

Adding the targeted therapy ribociclib to hormone therapy significantly improved overall survival (OS) in premenopausal patients with advanced hormone receptor-positive (HR+) breast cancer, according to results of the MONALEESA-7 Phase III clinical trial led by researchers at The University of Texas MD Anderson Cancer Center.

3 Jun 2019

Oral androgen receptor inhibitor improves outcomes for men with mHSPC

Enzalutamide, an oral androgen receptor inhibitor, can improve outcomes for men with metastatic hormone-sensitive prostate cancer, according to a large study presented by Christopher Sweeney, MBBS of Dana-Farber Cancer Institute's Lank Center for Genitourinary Oncology, during the American Society of Clinical Oncology Annual Meeting.

3 Jun 2019

Nearly all women treated for breast cancer suffer from health problems, finds study

Nearly all women who have been treated for non-metastatic breast cancer suffer from health problems after primary treatment.

21 May 2019

Inhibition of ribosome biogenesis as new treatment strategy for advanced cancers

Nearly ninety per cent of all cancer patient deaths are due to metastasis. A study from Uppsala University shows that a process that allows the cells to metastasize is aided by the synthesis of new ribosomes, the cell components in which proteins are produced.

8 May 2019

New method could lead to more personalized treatment of advanced prostate cancer

Researchers at Karolinska Institutet in Sweden have identified blood-based biomarkers that may determine which patients will benefit from continued hormonal therapy for advanced prostate cancer.

3 May 2019

Updated ASTRO/AUA Guideline on adjuvant and salvage radiotherapy after prostatectomy

The American Society for Radiation Oncology and the American Urological Association today announced updates to their joint clinical guideline on adjuvant and salvage radiotherapy after prostatectomy in patients with and without evidence of prostate cancer recurrence to include new published research related to adjuvant radiotherapy.

1 May 2019

Multigene test helps doctors to make effective treatment decisions for breast cancer patients

A breast cancer test has been found that helps doctors make treatment decisions for some breast cancer patients, following research carried out at Queen Mary University of London and funded by Cancer Research UK.

30 Apr 2019

FDA extends indication of metastatic breast cancer treatment to include male patients

The U.S. Food and Drug Administration today is extending the indication of Ibrance (palbociclib) capsules in combination with specific endocrine therapies for hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer in male patients.

5 Apr 2019

Breast cancer survivors more optimistic about changes occurred due to their illness

Two years after diagnosis, breast cancer survivors have four times more positive than negative thoughts about changes they experienced because of their illness, a new study found.

27 Feb 2019

Castration-resistant metastatic prostate cancer responds to combination of immune checkpoint inhibitors

Some patients with metastatic prostate cancer respond to a combination of immune checkpoint inhibitors after hormonal therapy and chemotherapy have failed, according to early results from a clinical trial led by investigators at The University of Texas MD Anderson Cancer Center presented today at the American Society of Clinical Oncology Genitourinary Cancers Symposium in San Francisco.

15 Feb 2019

New machine learning method predicts if atypical ductal hyperplasia will turn cancerous

Atypical ductal hyperplasia is a breast lesion associated with a four- to five-fold increase in the risk of breast cancer.

13 Feb 2019

Researchers unravel path of metallodrug in a breast cancer cell

Some types of cancer cannot be treated with classical chemotherapy. Scientists from Inserm, CNRS, Sorbonne University, PSL university, University Grenoble Alpes and ESRF, the European Synchrotron, are working on a metallorganic molecule as an antitumor drug.

4 Feb 2019

Stroke risk factors rise in post-menopausal women diagnosed with breast cancer

Risk factors for stroke rise sharply in post-menopausal women in the first year after they are diagnosed with breast cancer, according to preliminary research to be presented in Honolulu at the American Stroke Association's International Stroke Conference 2019, a world premier meeting for researchers and clinicians dedicated to the science and treatment of cerebrovascular disease.

30 Jan 2019