Hormone News and Research

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A hormone is a chemical released by one or more cells that affects cells in other parts of the organism. Only a small amount of hormone is required to alter cell metabolism. It is essentially a chemical messenger that transports a signal from one cell to another.

New form of immunotherapy increases survival in children with neuroblastoma

Administering a new form of immunotherapy to children with neuroblastoma, a nervous system cancer, increased the percentage of those who were alive and free of disease progression after two years, according to researchers at the University of California, San Diego School of Medicine and fellow institutions. The percentage rose from 46 percent for children receiving a standard therapy to 66 percent for children receiving immunotherapy plus standard therapy, according to the study published in the Sept. 30, 2010 issue of the New England Journal of Medicine.

30 Sep 2010

HRT therapy can increase breast cancer risk

Breast cancer is one of the most common cancers, affecting up to one in eight women during their lives in Europe, the UK and USA. Large population studies such as the Women's Health Initiative and the Million Women Study have shown that synthetic sex hormones called progestins used in hormone replacement therapy, HRT, and in contraceptives can increase the risk of breast cancers.

30 Sep 2010

New immunotherapy regimen improves survival rate in children with neuroblastoma: Research

30 Sep 2010

Physical activity reduces risk for womb cancer

Women who exercise and keep active are around 30 per cent less likely to develop womb cancer than couch potatoes - according to a new study published in the British Journal of Cancer today.

30 Sep 2010

Medivation and Astellas commence MDV3100 second Phase 3 clinical trial in advanced prostate cancer

Medivation, Inc. and Astellas Pharma Inc. today announced treatment of the first patient in a second Phase 3 clinical trial of the investigational drug MDV3100, which expands the Phase 3 development of the novel, triple-acting oral androgen receptor antagonist into an earlier-stage patient population. Known as PREVAIL, the trial will evaluate MDV3100 in men with advanced prostate cancer who have not yet received chemotherapy. Initiation of the PREVAIL trial triggers a milestone payment to Medivation under its collaboration agreement with Astellas.

29 Sep 2010

Stressed men tend to withdraw socially while women seek emotional support: Study

A new study by USC researchers reveals that stressed men looking at angry faces had diminished activity in the brain regions responsible for understanding others' feelings.

29 Sep 2010

Study finds PEM scanners equivalent to breast MRI in detecting cancerous lesions

In a prospective study published in the European Journal of Nuclear Medicine and Molecular Imaging, researchers at Boca Raton Regional Hospital (Boca Raton, FL) showed that Positron Emission Mammography (PEM) and breast MRI had comparably high ability to detect cancerous lesions.

29 Sep 2010

Intrauterine devices for treatment of endometrial cancer

Intrauterine devices, originally developed as contraceptives, can also be used to treat and cure cancer of the endometrium according to new research published online in the cancer journal, Annals of Oncology today (Wednesday 29 September). The finding opens the way for young women with the disease, which affects the lining of the womb, to be treated without the need for a hysterectomy, thus preserving their fertility until they have had all the children they want.

29 Sep 2010

Researchers find radical prostatectomy provides high survival rates

In one of the first studies to focus exclusively on the outcomes after treatment for patients with high-risk prostate cancer researchers have found that surgery provides high survival rates.

28 Sep 2010

Bayer’s new oral contraceptive receives FDA approval

Bayer HealthCare Pharmaceuticals Inc. today announced that the U.S. Food and Drug Administration has approved a new oral contraceptive, Beyaz (drospirenone / ethinyl estradiol / levomefolate calcium tablets and levomefolate calcium tablets).

28 Sep 2010

KAI Pharmaceuticals enrolls patients in Phase 1b study of KAI-4169 for treatment of SHPT

KAI Pharmaceuticals, Inc., a privately held drug discovery and development company, today announced enrollment of the first patients in a Phase 1b study of KAI-4169, a novel pharmaceutical agent being tested for the treatment of secondary hyperparathyroidism, which is a frequent and serious complication of end-stage renal disease.

27 Sep 2010

Breast cancer survivors with functional limitations more likely to die of poorer health: Study

Basic physical limitations following breast cancer treatment can have far-reaching consequences that substantially affect how long a patient lives.

27 Sep 2010

OncoGenex initiates OGX-427 Phase 2 trial for metastatic prostate cancer

OncoGenex Pharmaceuticals, Inc. announced today the initiation of a randomized, controlled, investigator sponsored Phase 2 trial of OGX-427 in men with metastatic prostate cancer.

27 Sep 2010

Researchers find stress-activating factors can control genes

Stress has become one of the major disease states in the developed world. Researchers from Dr.Klaus Hansen's group at BRIC, University of Copenhagen, have just shown that external factors can stress our cells through the control of our genes. "We found that stress-activating factors can control our genes by turning on certain genes that were supposed to be silenced.

27 Sep 2010

Study finds postmenopausal hormone therapy increases ovarian cancer risk

Compared with women who have never taken hormone therapy, those who currently take it or who have taken it in the past are at increased risk of ovarian cancer, regardless of the duration of use, the formulation, estrogen dose, regimen or route of administration, according to a study in the July 15 issue of JAMA.

27 Sep 2010

Calcitonin combination therapy may help treat osteoarthritis: Study

Tarsa Therapeutics, Inc. and Unigene Laboratories, Inc. today reported preclinical data showing that calcitonin may have synergistic effects in combination with other drugs in reducing the collagen degradation associated with osteoarthritis.

27 Sep 2010

New Concordia research links hormones with attention and learning

Feeling a little sluggish and having trouble concentrating? Hormones might be to blame according to new research from Concordia University published in the journal Brain and Cognition. The study shows that high estrogen levels are associated with an inability to pay attention and learn - the first such paper to report how this impediment can be due to a direct effect of the hormone on mature brain structures.

24 Sep 2010

Enobia announces positive results from ENB-0040 Phase II juvenile clinical trial for hypophosphatasia

Enobia Pharma today announced positive results for its Phase II juvenile clinical trial of ENB-0040 (asfotase alfa), an experimental bone-targeted enzyme replacement therapy intended for the treatment of hypophosphatasia (HPP). Hypophosphatasia is a rare, inherited, and sometimes fatal metabolic bone disease that affects individuals of all ages.

24 Sep 2010

Concerted effort yields significant progress in reducing depression, HIV/AIDS, and osteoporosis in women

A concerted effort to boost research on women's health over the last two decades has lessened the burden of disease and reduced deaths among women due to cardiovascular disease, breast cancer, and cervical cancer, says a new report from the Institute of Medicine. The effort has yielded less but still significant progress in reducing the effects of depression, HIV/AIDS, and osteoporosis on women, added the committee that wrote the report.

24 Sep 2010

Yoga, Tai Chi effective in treating fibromyalgia

This syndrome is often accompanied by fatigue, bowel disturbances, and urinary difficulty. Fibromyalgia can affect your daily activity, your sleep, and even your thinking when you're worn out and experiencing "brain fog." That's a term used by Henri Roca, MD, Medical Director at Greenwich Hospital's Center for Integrative Medicine in Cos Cob, Connecticut.

24 Sep 2010

Hormone News and Research

Further Reading

New form of immunotherapy increases survival in children with neuroblastoma

HRT therapy can increase breast cancer risk

New immunotherapy regimen improves survival rate in children with neuroblastoma: Research

Physical activity reduces risk for womb cancer

Medivation and Astellas commence MDV3100 second Phase 3 clinical trial in advanced prostate cancer

Stressed men tend to withdraw socially while women seek emotional support: Study

Study finds PEM scanners equivalent to breast MRI in detecting cancerous lesions

Intrauterine devices for treatment of endometrial cancer

Researchers find radical prostatectomy provides high survival rates

Bayer’s new oral contraceptive receives FDA approval

KAI Pharmaceuticals enrolls patients in Phase 1b study of KAI-4169 for treatment of SHPT

Breast cancer survivors with functional limitations more likely to die of poorer health: Study

OncoGenex initiates OGX-427 Phase 2 trial for metastatic prostate cancer

Researchers find stress-activating factors can control genes

Study finds postmenopausal hormone therapy increases ovarian cancer risk

Calcitonin combination therapy may help treat osteoarthritis: Study

New Concordia research links hormones with attention and learning

Enobia announces positive results from ENB-0040 Phase II juvenile clinical trial for hypophosphatasia

Concerted effort yields significant progress in reducing depression, HIV/AIDS, and osteoporosis in women

Yoga, Tai Chi effective in treating fibromyalgia

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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