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Revolutionizing disease prediction: MILTON framework utilizes biobank datasets to identify 3,213 diseases

By integrating multi-omics data, MILTON improves disease prediction and biomarker identification, advancing the field of preventative medicine and diagnostics.

17 Sep 2024

Monoclonal antibodies could help provide an answer to antimicrobial resistance

Monoclonal antibodies – treatments developed by cloning a cell that makes an antibody – could help provide an answer to the growing problem of antimicrobial resistance, say scientists.

16 Sep 2024

Long-term benefits of immunotherapy highlighted in advanced melanoma and other cancers

Immunotherapy, which works by enabling the body's immune system to recognize and destroy cancer cells improves long-term overall survival in patients with advanced melanoma in results from large international studies reported at ESMO 2024.

16 Sep 2024

UC study explores airborne transmission of MRSA in hospital settings

Even in a post-pandemic world, frontline health care workers face many occupational challenges, and exposure to infection is among them.

16 Sep 2024

Caregiver food insecurity impacts outcomes of pediatric hospitalizations

Food insecurity, which is the limited or uncertain availability of nutritionally adequate and safe food, is associated with poor health outcomes and the increased need to use health care services.

16 Sep 2024

Study reveals link between socioeconomic inequality and the risk of age-related macular degeneration

A recent study conducted by researchers from Shanghai Jiao Tong University School of Medicine and Fudan University has revealed a significant association between socioeconomic status (SES) inequality and the risk of developing age-related macular degeneration (AMD).

16 Sep 2024

AI-based system reduces hospital deaths by identifying high-risk patients

Can artificial intelligence (AI) help reduce deaths in hospital? An AI-based system was able to reduce risk of unexpected deaths by identifying hospitalized patients at high risk of deteriorating health, found new research published in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.240132.

16 Sep 2024

Review highlights mitochondrial dysfunction in cholestatic liver injury

Bile acids are essential signaling molecules derived from cholesterol metabolism in the liver and are crucial for the digestion and absorption of fats.

16 Sep 2024

Hormone therapy found to improve insulin sensitivity in menopausal women

Menopausal women are at greater risk of insulin resistance as a result of declining estrogen levels. Previous studies evaluating the potential benefits of hormone therapy on insulin resistance have produced mixed results.

16 Sep 2024

Combination immunotherapy yields 10-year survival for metastatic melanoma patients

Long-term data from a landmark international trial show about half of patients with metastatic melanoma treated with a combination of immune checkpoint inhibitors survive cancer-free for 10 years or more, according to a new report from Weill Cornell Medicine and Dana-Farber Cancer Center investigators and their colleagues.

16 Sep 2024

Common diabetes medication slows growth of precancerous esophageal cells, study shows

A common diabetes medication, metformin, slows the growth of precancerous cells in the oesophagus while some metabolic conditions accelerate it, suggests a new study.

16 Sep 2024

NIH funds new research to combat emerging viruses

Albert Einstein College of Medicine has received a five-year, $14 million per year grant from the National Institute of Allergy and Infectious Diseases (NIAID) to participate in a broad national effort to develop "plug-and-play" vaccines and antibody-based therapies against a wide range of emerging viruses. The grant is part of NIAID's new Research and Development of Vaccines and Monoclonal Antibodies for Pandemic Preparedness (ReVAMPP) Network, which was announced earlier today.

14 Sep 2024

AI-powered treatment allocation improves public health outcomes

A new study sheds light on a promising approach using machine learning to more effectively allocate medical treatments during a pandemic or any time there's a shortage of therapeutics.

14 Sep 2024

Scientists develop novel technique to combat T cell exhaustion

Fighting cancer is exhausting for T cells. Hostile tumor microenvironments can drain their mitochondrial activity, leading to a condition known as T cell exhaustion. This phenomenon also hinders adoptive cell therapies, in which healthy, tumor-targeting T cells are infused into patients with cancer. A novel method to boost mitochondrial activity and charge up T cells is needed.

14 Sep 2024

Mount Sinai researchers uncover genetic basis of fibromuscular dysplasia

Mount Sinai researchers have identified a key driver of a blood vessel disorder known as fibromuscular dysplasia (FMD) which affects up to five percent of the adult population and can lead to high blood pressure, heart attack, or stroke.

14 Sep 2024

Real-world data reveals factors associated with long-term weight loss in obesity

A Cleveland Clinic study identified key factors that can impact the long-term weight loss of patients with obesity who were prescribed injectable semaglutide or liraglutide for the treatment of type 2 diabetes or obesity. The study was published in JAMA Network Open.

14 Sep 2024

Hospital News and Research

Revolutionizing disease prediction: MILTON framework utilizes biobank datasets to identify 3,213 diseases

Monoclonal antibodies could help provide an answer to antimicrobial resistance

Long-term benefits of immunotherapy highlighted in advanced melanoma and other cancers

UC study explores airborne transmission of MRSA in hospital settings

Caregiver food insecurity impacts outcomes of pediatric hospitalizations

Study reveals link between socioeconomic inequality and the risk of age-related macular degeneration

AI-based system reduces hospital deaths by identifying high-risk patients

Review highlights mitochondrial dysfunction in cholestatic liver injury

Hormone therapy found to improve insulin sensitivity in menopausal women

Combination immunotherapy yields 10-year survival for metastatic melanoma patients

Common diabetes medication slows growth of precancerous esophageal cells, study shows

NIH funds new research to combat emerging viruses

AI-powered treatment allocation improves public health outcomes

Scientists develop novel technique to combat T cell exhaustion

Mount Sinai researchers uncover genetic basis of fibromuscular dysplasia

Real-world data reveals factors associated with long-term weight loss in obesity

New drug shows strong activity against brain metastases in HER2-positive breast cancer

New biomarker helps differentiate Alzheimer’s from primary 4-repeat tauopathies

National survey reveals vaccine hesitancy ahead of flu and COVID-19 season

Breakthrough study sheds light on mechanisms behind the spread of gastric cancer to the peritoneum

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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