Hot Flash News and Research

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Hot Flash is a sudden, temporary onset of body warmth, flushing, and sweating (often associated with menopause).

Is rapid transition through menopause linked to earlier onset of heart disease?

An evaluation of 203 women as part of the multifaceted Los Angeles Atherosclerosis Study (LAAS) found that those who transitioned more quickly through menopause were at increased risk for a higher rate of progression of "preclinical atherosclerosis" - narrowing of arteries caused by the thickening of their walls.

29 Jan 2009

FDA approves injectable drug degarelix for advanced prostate cancer

The U.S. Food and Drug Administration recently approved the injectable drug degarelix, the first new drug in several years for prostate cancer.

29 Dec 2008

Fruits, vegetables and fiber may cut risk of breast cancer recurrence in women without hot flashes

A secondary analysis of a large, multicenter clinical trial has shown that a diet loaded with fruits, vegetables and fiber and somewhat lower in fat compared to standard federal dietary recommendations cuts the risk of recurrence in a subgroup of early-stage breast cancer survivors - women who didn't have hot flashes - by approximately 31 percent.

15 Dec 2008

Estrogen therapy can help control metastatic breast cancer

For breast cancer survivors, the idea of taking estrogen pills is almost a taboo. In fact, their doctors give them drugs to get rid of the hormone because it can fuel the growth of breast cancer.

12 Dec 2008

New cream for vaginal dryness approved

Barr Pharmaceuticals, Inc. has announced that the U.S. Food and Drug Administration (FDA) has approved its subsidiary Duramed Pharmaceuticals, Inc.'s New Drug Application (NDA) for Synthetic Conjugated Estrogens-A (SCE-A) 0.625 mg/g Vaginal Cream.

1 Dec 2008

Concert Pharmaceuticals initiates CTP-347 phase I clinical trial

Concert Pharmaceuticals, Inc. announced today that it has initiated a Phase I study in healthy volunteers to evaluate the safety, tolerability and pharmacokinetics of CTP-347, a novel deuterium-containing serotonin modulator created by Concert researchers.

25 Sep 2008

Chronic exposure to estrogen impairs some cognitive functions

University of Illinois researchers report this week that chronic exposure to estradiol, the main estrogen in the body, diminishes some cognitive functions. Rats exposed to a steady dose of estradiol were impaired on tasks involving working memory and response inhibition, the researchers found.

3 Aug 2008

Hormone deprivation therapy - used for prostate cancer - may cause recall and concentration problems

A recent review of the literature has found that hormone deprivation therapy, a commonly used treatment for prostate cancer, may have subtle adverse effects on cognition in patients--such as in the ability to recall and concentrate.

28 Jul 2008

Sleep and menopause

Difficulty falling asleep and staying asleep increase as women go through menopause according to research by Rush University Medical Center. Waking up earlier than planned also increases through late perimenopause but decreases when women become postmenopausal. The study is published in the July 1 issue of the journal SLEEP.

1 Jul 2008

Hot flashes underreported and linked to forgetfulness

Women in midlife underreport the number of hot flashes that they experience by more than 40 percent, and these hot flashes are linked to poor verbal memory, according to a study by researchers at the University of Illinois at Chicago.

16 Jun 2008

Simple blood test could indicate higher risk for coronary events in women after post-menopausal hormone therapies

A research study has found that a simple blood test may indicate whether post-menopausal hormone therapies present an elevated risk of a heart attack.

22 May 2008

Femara helps protect against return of breast cancer after completing Tamoxifen therapy

Women may reduce the risk of their breast cancer returning by starting treatment with Femara (letrozole tablets) anywhere from one to seven years after finishing tamoxifen therapy, according to a new analysis published in the Journal of Clinical Oncology.

11 Mar 2008

$Hormone refractory prostate cancers more likely to spread to other organs$

Hormone refractory prostate cancers more likely to spread to other organs

Prostate cancers that are resistant to androgen deprivation therapy are more invasive and more likely to spread to other organs than androgen dependent prostate cancers, UCLA cancer researchers have found.

21 Feb 2008

More support needed for menopausal women in rural areas

Good social support and reliable information are essential for women who find menopause an intense and life-altering experience, especially if they live in rural areas where health services are patchy or inaccessible.

20 Feb 2008

$Hormone refractory prostate cancers more likely to spread to other organs$

Hormone refractory prostate cancers more likely to spread to other organs

20 Feb 2008

Hot flashes may be getting an unfair rap for disrupting women's sleep at midlife

Studies have often reported that sleep problems increase during the transition into menopause, reinforcing the idea that hot flashes are to blame. But even under controlled conditions in sleep laboratories, the connection between hot flashes and sleep disruption remains unclear, reports the February 2008 issue of Harvard Women's Health Watch.

8 Feb 2008