Hydrocephalus News and Research

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Hydrocephalus is an abnormal buildup of cerebrospinal fluid in the ventricles of the brain.

Adjustable shunt effectively alleviates hydrocephalus pressure

Using a shunt with an adjustable Strata valve that is initially set at the highest setting so it can be titrated down is a worthwhile approach to treat idiopathic normal pressure hydrocephalus.

25 Feb 2013

Repeat angiography worthwhile in subarachnoid hemorrhage

A second or even third attempt at catheter angiography may reveal vascular abnormalities after an initial negative result in patients with subarachnoid hemorrhage, say researchers.

14 Jan 2013

Researchers find link between brain infections and climate in sub-Saharan Africa

The amount of rainfall affects the number of infant infections leading to hydrocephalus in Uganda, according to a team of researchers who are the first to demonstrate that these brain infections are linked to climate.

7 Jan 2013

Bypass option for ‘unclippable’ giant cerebral aneurysms

Extracranial–intracranial bypass is a “durable” treatment option for giant middle cerebral artery aneurysms that cannot be clipped, say US researchers.

7 Dec 2012

Researchers discover new cause of hydrocephalus

Researchers at the University of Iowa have discovered a new cause of hydrocephalus, a devastating neurological disorder that affects between one and three of every 1,000 babies born. Working in mice, the researchers identified a cell signaling defect, which disrupts immature brain cells involved in normal brain development.

20 Nov 2012

Dysfunction in SRGAP3 protein causes developmental brain disorders

A new research discovery has the potential to revolutionize the biological understanding of some childhood psychiatric disorders. Specifically, scientists have found that when a single protein involved in brain development, called "SRGAP3," is malformed, it causes problems in the brain functioning of mice that cause symptoms that are similar to some mental health and neurological disorders in children.

1 Nov 2012

Study finds high internet use by caregivers of children with hydrocephalus

When faced with disease, patients and caregivers now readily turn to the Internet for information and emotional support. This is particularly true in the case of caregivers of children with hydrocephalus.

25 Oct 2012

Shunting may not ward off poor hydrocephalus cognitive outcomes

Around half of patients with idiopathic normal-pressure hydrocephalus will develop dementia, despite responding to shunting, study findings suggest.

19 Oct 2012

No ‘July phenomenon’ for patients undergoing neurosurgery at teaching hospitals

For patients undergoing neurosurgery at teaching hospitals, there's no "July phenomenon" of increased death and complication rates when new residents start their training, reports a study in the September issue of Neurosurgery, official journal of the Congress of Neurological Surgeons.

24 Sep 2012

Recurrent glioblastoma: consider after effects before choosing palliative surgery

Before suggesting surgery as palliative therapy for patients with recurrent glioblastoma, physicians should consider the impact of morbidities on quality of life, suggest researchers from Italy.

20 Sep 2012

GE Healthcare announces data from [18F]flutemetamol phase III studies on Alzheimer's

GE Healthcare today announced pooled results from phase III brain autopsy and biopsy studies on the investigational PET amyloid imaging agent, [18F]flutemetamol, which showed a strong concordance between [18F]flutemetamol images and Alzheimer's disease-associated beta amyloid brain pathology.

11 Sep 2012

Hydrocephalus dictates age-related SAH outcomes

Age is only predictive of poor outcome after aneurysmal subarachnoid hemorrhage because of its association with hydrocephalus, say researchers.

10 Aug 2012

FDA approves Codman’s MEDSTREAM Programmable Infusion System

Codman & Shurtleff, Inc. (Codman), the global neurological device company, has received U.S. Food and Drug Administration (FDA) approval through a PMA supplement for its MEDSTREAM Programmable Infusion System, an implantable infusion pump and catheter system used in the treatment of spasticity, a movement disorder often caused by stroke, cerebral palsy, multiple sclerosis or spinal cord injury.

9 Aug 2012

Sinai Hospital to help investigate health and safety of astronauts in long-duration spaceflight

Sinai Hospital of Baltimore has been awarded one of 29 grants by the National Space Biomedical Research Institute (NSBRI) and NASA's Human Research Program to help investigate questions about astronaut health and performance on future deep-space exploration missions.

31 Jul 2012

Toshiba’s Vantage Titan 1.5T and 3T MR systems can help visualize CSF bulk flow

Cerebral Spinal Fluid (CSF), the clear water-like fluid that surrounds the brain and the spinal cord, plays a key role in maintaining balanced brain dynamics. For the first time, CSF bulk flow can now be visualized non-invasively with Toshiba America Medical Systems, Inc.'s Vantage Titan 1.5T and 3T MR systems.

30 Jul 2012

LSDF announces $570,000 in awards to support commercialization of new health-related products

The Life Sciences Discovery Fund (LSDF) today announced nearly $570,000 in awards in its inaugural corporate grant program to support commercialization of new health and health-care products by four early-stage Washington-based companies.

25 Jul 2012

Mechanism of CSF drainage benefits unclear in normal pressure hydrocephalus

The beneficial effect of removing cerebrospinal fluid from patients with normal pressure hydrocephalus is not mediated by reduction of ventricle volume, research suggests.

20 Jul 2012

Researchers discover new gene mutations associated with megalencephaly

A research team led by Seattle Children's Research Institute has discovered new gene mutations associated with markedly enlarged brain size, or megalencephaly.

30 Jun 2012

Experts in fluid mechanics to study Chiari malformation

Expertise in fluid mechanics at The University of Akron has attracted funding for a new research center designed to help physicians better diagnose and treat an unusual cause of pain in the head, neck and shoulders. Chiari malformation is a disorder of the neurologic system caused in part by an imbalance in brain and spinal fluid.

28 Jun 2012

Apple iPad 2 can affect programmable shunt valve in children with hydrocephalus

Researchers at the University of Michigan have found that the Apple iPad 2 can interfere with settings of magnetically programmable shunt devices, which are often used to treat children with hydrocephalus.

27 Jun 2012