Hyperglycemia News and Research

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Hyperglycemia occurs when you have a higher than usual level of glucose in your blood. This can happen shortly after you have eaten a big meal and is not a problem if your glucose level returns to normal. Cells remove glucose from the blood in response toinsulin. If your pancreas doesn't make enough insulin, glucose can't enter the cells and remains in the blood. Blood glucose levels can also get too high if cells areunable to respond to insulin properly (insulinresistance). Without glucose, your cells are unable to make energy and can't function properly.

A gloomy outlook for type 1 diabetes in children and adolescents by 2050

A study published in The Lancet Diabetes and Endocrinology journal estimates the global incidence of type 1 diabetes in children and adolescents using microsimulation models.

5 Jan 2023

NCI-led clinical trial results in the first approval of a treatment for advanced alveolar soft part sarcoma

A clinical trial led by the National Cancer Institute (NCI), part of the National Institutes of Health, has resulted in the first approval of a treatment for advanced alveolar soft part sarcoma (ASPS).

28 Dec 2022

Researchers identify a new pathogenic mechanism for diabetes onset in MODY3

In order to treat patients with diabetes in the best possible way it is necessary to understand the disease mechanism. MODY type 3 (MODY3) is a monogenic hereditary form of diabetes, that is caused by a genetic defect in the HNF1A gene.

22 Dec 2022

Revised guidelines for diabetes care

A recent Diabetes Care journal paper summarized the latest recommendations offered to people with diabetes to improve their health and well-being.

15 Dec 2022

How the COVID-19 pandemic impacted the treatment pancreatic cancer patients

Researchers investigates the impact of the COVID-19 pandemic on pancreatic cancer services in England.

11 Dec 2022

Addition of capivasertib to fulvestrant doubles progression-free survival in HR-positive breast cancer patients

In patients with hormone receptor (HR)-positive, HER2-negative tumors resistant to aromatase inhibitors, addition of the investigational AKT inhibitor capivasertib to fulvestrant (Faslodex) doubled the median progression-free survival compared with placebo plus fulvestrant in the phase III CAPItello-291 clinical trial, according to results presented at the San Antonio Breast Cancer Symposium, held December 6-10, 2022.

9 Dec 2022

Study explores the risk of new-onset diabetes mellitus following SARS-CoV-2 infections

Researchers evaluated individuals who had SARS-CoV-2 infections and were diagnosed with diabetes mellitus within six months of the onset of COVID-19 to understand the temporal relationship between SARS-CoV-2 infections and diabetes mellitus.

8 Dec 2022

Study provides novel therapeutic targets for enhancing the antitumor immunity of γδ-T cells in diabetes

A research team at LKS Faculty of Medicine, The University of Hong Kong (HKUMed) discovered that high glucose impairs the antitumor activity of immune effector γδ-T cells, which contributes to the increased cancer risk in diabetes and that metabolic reprogramming by glucose control may improve the antitumor activity of γδ-T cells.

30 Nov 2022

SARS-CoV-2 can cause hyperglycemia in cats

In a recent study published in The Journal of Infectious Diseases, researchers explored the association between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and hyperglycemia in cats.

30 Nov 2022

Meta-analysis reviews the incidence of new-onset diabetes in COVID-19 survivors

Researchers estimated the incidence of new-onset diabetes in survivors of coronavirus disease 2019 (COVID-19) employing random-effects meta-analyses using the generic inverse variance method.

30 Nov 2022

Endogenous system may be responsible for delayed onset of diabetic retinopathy

About one third of patients with diabetes mellitus (DM) develop diabetic retinopathy (DR), a leading cause of blindness in working-age individuals. DR typically develops after many years of DM, and some patients do not develop DR for more than 50 years.

29 Nov 2022

Higher incidence of C. glabrata bloodstream infections in patients with diabetes indicates potential fluconazole resistance

In a recent study, researchers analyzed data collected over ten years to understand the clinical characteristics, epidemiology, outcomes, and management of bloodstream Candida infections in diabetes patients.

29 Nov 2022

FDA approves first-ever type 1 diabetes delaying drug Tzield (teplizumab-mzwv)

On November 17, 2022, the US Food and Drug Administration (FDA) approved a pathbreaking new drug called Tzield. This injectable formulation contains a combination of two drugs that could push back the onset of type 1 diabetes (T1D) in adults at stage 3 and children aged eight years or more at stage 2.

20 Nov 2022

Ketogenic diet may show more promising results than Mediterranean diets in short-term type 2 diabetes management

Researchers evaluated the short-term impact of the very-low-calorie ketogenic diet (VLCKD) and Mediterranean diet (MD) on the gut microbiota (GM) of obese patients with new-onset type II diabetes (T2DM).

15 Nov 2022

The direct and indirect effects of COVID-19 on people with type 1 and type 2 diabetes

A recent study published in The Lancet Diabetes & Endocrinology discussed the impact of COVID-19 on individuals with diabetes.

9 Nov 2022

Administering steroids during heart surgery does not improve post-operative outcomes in infants

The largest clinical trial ever conducted in infants younger than age 1 undergoing heart surgery with cardiopulmonary bypass found that administering steroids during surgery did not improve post-operative outcomes compared to placebo, according to preliminary late-breaking research to be presented at the American Heart Association's Scientific Sessions 2022.

7 Nov 2022

New evidence-based clinical guidelines expand patient eligibility for metabolic and bariatric surgery

Two of the world's leading authorities on bariatric and metabolic surgery have issued new evidence-based clinical guidelines that among a slew of recommendations expand patient eligibility for weight-loss surgery and endorse metabolic surgery for patients with type 2 diabetes beginning at a body mass index (BMI) of 30, a measure of body fat based on a person's height and weight and one of several important screening criteria for surgery.

21 Oct 2022

Hyperglycemia News and Research

Further Reading

A gloomy outlook for type 1 diabetes in children and adolescents by 2050

NCI-led clinical trial results in the first approval of a treatment for advanced alveolar soft part sarcoma

Researchers identify a new pathogenic mechanism for diabetes onset in MODY3

Revised guidelines for diabetes care

How the COVID-19 pandemic impacted the treatment pancreatic cancer patients

Addition of capivasertib to fulvestrant doubles progression-free survival in HR-positive breast cancer patients

Study explores the risk of new-onset diabetes mellitus following SARS-CoV-2 infections

Study provides novel therapeutic targets for enhancing the antitumor immunity of γδ-T cells in diabetes

SARS-CoV-2 can cause hyperglycemia in cats

Meta-analysis reviews the incidence of new-onset diabetes in COVID-19 survivors

Endogenous system may be responsible for delayed onset of diabetic retinopathy

Higher incidence of C. glabrata bloodstream infections in patients with diabetes indicates potential fluconazole resistance

FDA approves first-ever type 1 diabetes delaying drug Tzield (teplizumab-mzwv)

Ketogenic diet may show more promising results than Mediterranean diets in short-term type 2 diabetes management

The direct and indirect effects of COVID-19 on people with type 1 and type 2 diabetes

Administering steroids during heart surgery does not improve post-operative outcomes in infants

New evidence-based clinical guidelines expand patient eligibility for metabolic and bariatric surgery

Does skin inflammation exacerbate COVID-19?

Do hypertension, dyslipidemia, and new-onset diabetes mellitus play a part in post-COVID sequelae?

Scientists identify group of genes shared between COVID-19 and diabetic kidney disease

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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