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Evaluating severity of influenza infection in ferrets with COVID-19 history

In a new study, researchers investigated the effect of SARS-CoV-2 exposure on the severity of influenza in ferrets.

28 Mar 2022

Excessive neuropeptide secretion in the lungs can lead to fluid buildup and poor oxygenation

COVID-19 has put a spotlight on the pulmonary and nervous systems, but there is still much to learn about how they interact. Researchers at University of California San Diego School of Medicine recently explored this relationship in the context of a childhood lung disease, but their findings may also apply to COVID-19 symptoms.

17 Mar 2022

Dual therapeutic potential of zapnometinib against COVID-19

Researchers assessed the impact of the drug zapnometinib on human immune response against coronavirus disease 2019.

2 Mar 2022

Potential of a SARS-CoV-2 immunoPET approach to study COVID-19 dynamics in total body in rhesus macaques

In a recent study an immunoPET technique that the authors were using to analyze SIV was adapted to evaluate the spatiotemporal dynamics of SARS-CoV-2 infection in a rhesus macaque model.

2 Mar 2022

Study shows mink can be infected by Omicron and efficiently transmit the virus to other mink

Researchers have been examining the pathology and spread of the Omicron variant in mink.

18 Feb 2022

Protective efficacy of BNT162b2 and Ad26.COV2.S against SARS-CoV-2 Omicron challenge in nonhuman primates

The study highlights the significance of mix-and-match vaccine regimens to diversify the immune responses against highly mutated variants of SARS-CoV-2 such as Omicron.

10 Feb 2022

Exploring the systemic infection of SARS-CoV-2 in a wild leopard in India

A new study focused on the pathomorphological and virological characterization of SARS-CoV-2 in naturally infected, wild Indian Leopard.

17 Jan 2022

Protein biomarkers in urine could be used to diagnose concussion and monitor recovery

Concussion can be frustratingly hard to diagnose and track. The injury doesn't show up on routine brain scans, and there is no definitive diagnostic test. It's usually diagnosed based on symptoms, and, in athletes, comparison with baseline testing if it was done. But concussion symptoms are non-specific, unreliable, and easily influenced by emotions.

17 Jan 2022

COVID-19 symptoms found to vary in different immune contexts

In a new study, researchers studied the kinetics of host response to SARS-CoV-2 infection in a Syrian hamster model, tracking disease pathology, viral loads, antibody responses, and inflammatory cytokine production in multiple organs.

11 Jan 2022

Patient decision aids for urologic conditions fall short of quality and readability standards

Online patient decision aids for common urologic conditions fall short of recommendations for readability and minimum standards for quality, reports a study in Urology Practice, an Official Journal of the American Urological Association.

19 Oct 2021

Scientists identify gene responsible for food-dependent form of Cushing's Syndrome

A team of scientists in Montreal and Paris has succeeded in identifying the gene responsible for the development of a food-dependent form of Cushing's Syndrome, a rare disease affecting both adrenal glands.

15 Oct 2021

A new synthetic multiantigen MVA vaccine COH04S1 effective against SARS-CoV-2

A new study utilized MVA to develop vaccine candidates that were subsequently evaluated in animal models of congenital cytomegalovirus disease.

19 Sep 2021

Vesicular stomatitis virus-based COVID vaccines demonstrate potent antiviral efficacy against SARS-CoV-2 variants

Scientists from the National Institutes of Health, USA, have recently demonstrated the immunogenicity and protective efficacy of two vesicular stomatitis virus (VSV)-based coronavirus disease 2019 (COVID-19) vaccines in hamsters.

6 Sep 2021

Researchers identify mechanism for formation of rare colorectal cancer subtype

Researchers from Rutgers Cancer Institute of New Jersey, the state's only National Cancer Institute-designated Comprehensive Cancer Center, recently discovered a mechanism to explain what drives the formation of mucinous colorectal adenocarcinoma (MAC), a rare subtype of colorectal cancer (CRC), and has also identified the genes responsible for the regulation of this mechanism.

25 Aug 2021

Patients with enlarged prostate may have lower chances of significant prostate cancer

A team of Beaumont Health researchers from Radiology, Radiation Oncology and Urology studied the relationship between benign prostatic hyperplasia, or BPH, and prostate cancer in 405 men by quantitatively looking at different parts of prostate tissue on MRI.

18 Aug 2021

Study reveals how high dietary fructose increases rates of obesity and cancers

Eating fructose appears to alter cells in the digestive tract in a way that enables it to take in more nutrients, according to a preclinical study from investigators at Weill Cornell Medicine and NewYork-Presbyterian.

18 Aug 2021

Role of neutrophil-epithelial interactions in SARS-CoV-2 infection

Researchers discuss the relationship between airway neutrophils and SARS-CoV-2 infection to determine the impact that neutrophils have on COVID-19.

15 Aug 2021

COVID-19 vaccine candidate that can be produced in yeast proves effective in macaques

Researchers in the United States have designed a modular protein subunit vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that elicited a strong immune response in macaques and prevented the animals from developing coronavirus disease 2019 (COVID-19).

15 Jul 2021

Feline model of SARS-CoV-2 infection imitates COVID-19 in humans

Researchers in the United States have validated a feline model of infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that closely imitates coronavirus disease 2019 (COVID-19) in humans.

15 Apr 2021

New exosome-coated stent repairs damaged tissue, heals vascular injury

Researchers from North Carolina State University have developed an exosome-coated stent with a "smart-release" trigger that could both prevent reopened blood vessels from narrowing and deliver regenerative stem cell-derived therapy to blood-starved, or ischemic, tissue.

6 Apr 2021