Hypertrophic Cardiomyopathy News and Research

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Hypertrophic cardiomyopathy is a condition that affects the heart’s ability to pump blood effectively due to the thickening (hypertrophy) of the heart muscle which becomes stiff as a result.

Ninerafaxstat shows good tolerability and safety in nonobstructive HCM patients

The investigational drug ninerafaxstat showed a good tolerability and safety profile, along with evidence of improvements in symptoms and exercise capacity among people with nonobstructive hypertrophic cardiomyopathy (HCM), according to results of a 12-week phase 2 trial presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

Small declines in blood lead levels linked to long-term cardiovascular health improvements

Through the Strong Heart Family Study, National Institutes of Health-supported researchers found that small declines in blood lead levels were associated with long-term cardiovascular health improvements in American Indian adults.

11 Jan 2024

Patients with heart conditions should practice good hygiene to prevent infective endocarditis

Patients with specific cardiac conditions such as valvular heart disease and congenital abnormalities, or those requiring a pacemaker, should practice good dental and skin hygiene to help prevent rare but potentially deadly infections of the heart's inner lining and valves, according to European Society of Cardiology (ESC) Guidelines on infective endocarditis, published online today in European Heart Journal.

25 Aug 2023

New ESC Guidelines on cardiomyopathies published online today

The European Society of Cardiology (ESC) Guidelines on cardiomyopathies are published online today in European Heart Journal.

25 Aug 2023

AHA scientific statement highlights evidence for shared decision-making in cardiovascular care

A new American Heart Association scientific statement highlights evidence that supports shared decision-making, a term that describes the process of ensuring patients have the knowledge and tools to make decisions about their health in collaboration with their professional health care team.

14 Aug 2023

Advanced scans can detect hypertrophic cardiomyopathy before symptoms appear

The research, funded by the British Heart Foundation and published in the journal Circulation, opens the prospect of treating the condition at the earliest stages.

19 Jul 2023

New scientific statement details treatment strategies for pediatric cardiomyopathy

Treating children with cardiomyopathy should be personalized based on the root cause, symptoms and progression of the condition in each child , according to a new American Heart Association scientific statement published today in the Association's flagship, peer-reviewed journal Circulation.

8 Jun 2023

New deep learning model lays the foundation for specialized diagnostic models

Mount Sinai researchers have developed an innovative artificial intelligence (AI) model for electrocardiogram (ECG) analysis that allows for the interpretation of ECGs as language. This approach can enhance the accuracy and effectiveness of ECG-related diagnoses, especially for cardiac conditions where limited data is available on which to train.

7 Jun 2023

CardioGen upgrade facilitates more accurate diagnosis of monogenic cardiovascular diseases

Over 2,800 cases, representing a 31% increase, added to BGI Genomics-led CardioGen's hereditary cardiovascular disease gene data.

From BGI Genomics 1 Jun 2023

Vigorous exercise not linked to increased risk of adverse events in people with hypertrophic cardiomyopathy

Vigorous exercise does not appear to increase the risk of death or life-threatening arrhythmia for people with hypertrophic cardiomyopathy (HCM), according to a study supported by the National Institutes of Health.

17 May 2023

Study reveals staggering toll of being Black in America: 1.6M excess deaths over 22 years

Research has long shown that Black people live sicker lives and die younger than white people.

16 May 2023

Extended ECG monitoring of patients with hypertrophic cardiomyopathy detects more arrhythmias

Thirty day electrocardiogram (ECG) monitoring in patients with hypertrophic cardiomyopathy (HCM) detects more arrhythmias than the standard 24 to 48 hours, according to late breaking science presented at EHRA 2023, a scientific congress of the European Society of Cardiology.

17 Apr 2023

New statement suggests next steps to interpret incidentally identified gene variants related to heart disease

Increasing use of genetic testing means people may discover they have a gene variant associated with some types of cardiovascular disease (CVD).

27 Mar 2023

Common scientific method to analyze DNA in early human embryos fails to accurately reflect gene edits

A commonly used scientific method to analyze a tiny amount of DNA in early human embryos fails to accurately reflect gene edits, according to new research led by scientists at Oregon Health & Science University.

7 Mar 2023

Most athletes with diagnosed and treated genetic heart disease experienced no cardiac events

Ninety-five percent of athletes with a diagnosed and treated genetic heart disease experienced no disease-triggered cardiac events, such as cardiogenic fainting or seizures, implantable cardio-defibrillator (ICD) shocks, sudden cardiac arrest or sudden cardiac death, during an average of seven years of follow up, according to a study being presented at the American College of Cardiology's Annual Scientific Session Together With the World Congress of Cardiology.

6 Mar 2023

Vigorous exercise does not increase risk of serious cardiac events in people with hypertrophic cardiomyopathy

People with the inherited heart condition hypertrophic cardiomyopathy (HCM) who exercised vigorously did not have an increased incidence of serious cardiac events during three years of follow-up compared with people who exercised moderately or were inactive, according to a study being presented at the American College of Cardiology's Annual Scientific Session Together With the World Congress of Cardiology.

6 Mar 2023

Study reveals a new pathway for how children and adults develop cardiomyopathy

Researchers have discovered how a gene that increases the risk of developing genetic heart disease functions, paving the way for new treatments.

2 Mar 2023

Genome editing prevents hypertrophic cardiomyopathy in mice

In a recent study published in the journal PLoS Digital Health, researchers pursued one-time cures for hypertrophic cardiomyopathy (HCM). They used a previously constructed murine model of HCM, designated as R403Q-129SvEv, to evaluate two different genetic therapies, as follows:

19 Feb 2023

Morristown Medical Center reaches significant milestone of performing over 4,000 TAVR

Morristown Medical Center's Gagnon Cardiovascular Institute's structural heart program reached a significant milestone of performing over 4,000 transcatheter aortic valve replacement (TAVR) procedures with well over 650 in 2022 alone.

10 Feb 2023

CardioGen automated interpretation system for diagnosis of monogenic cardiovascular diseases

Monogenic cardiovascular disease is a genetic disease in which cardiovascular damage is the only or main phenotype. The total current number of patients worldwide exceeds 10 million.

8 Feb 2023