Hypertrophic Cardiomyopathy News and Research

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Hypertrophic cardiomyopathy is a condition that affects the heart’s ability to pump blood effectively due to the thickening (hypertrophy) of the heart muscle which becomes stiff as a result.

SCT, Thermo Fisher Scientific collaborate to advance development of cardiac disease models

Stem Cell Theranostics announced today that they have successfully completed a research collaboration with Thermo Fisher Scientific focused on advancing the development of cardiac disease models derived from induced pluripotent stem cells using Thermo Fisher Scientific's suite of work flow reagents and SCT's patient biobank and proprietary disease modeling methods.

7 Oct 2015

Sticky, protein-rich gel improves cardiac function after simulated heart attacks

A sticky, protein-rich gel created by Johns Hopkins researchers appears to help stem cells stay on or in rat hearts and restore their metabolism after transplantation, improving cardiac function after simulated heart attacks, according to results of a new study.

25 Sep 2015

Study challenges new ESC Guidelines to identify high-risk HCM patients who need ICDs for prevention of sudden death

Hypertrophic cardiomyopathy (HCM), a genetic form of heart disease with thick heart walls, is the most common cause of sudden death in patients under 50. While only a minority of patients with HCM are at risk, the implantable cardioverter-defibrillator (ICD) can effectively prevent sudden death in those patients.

22 Sep 2015

Implantable defibrillators help patients with hypertrophic cardiomyopathy live longer

Newly published research led by the Minneapolis Heart Institute Foundation and Tufts Medical Center in Boston shows that implantable defibrillators (ICDs), along with other modern treatments, have reduced mortality rates and are helping patients with hypertrophic cardiomyopathy (HCM) live longer, including normal life expectancy.

12 Mar 2015

Understanding heart mutations that cause sudden cardiac arrest

New biosciences research at the University of Kent could point the way to greater understanding of the heart mutations that cause sudden cardiac arrest.

20 Jan 2015

UCSD researchers develop novel ultrasound technology to diagnose two heart conditions

Engineers at the University of California, San Diego have determined for the first time the impact of a ring-shaped vortex on transporting blood flow in normal and abnormal ventricles within the human heart. They worked with cardiologists at the Non-Invasive Cardiology Laboratory at Gregorio Marañon Hospital, in Madrid, Spain.

29 Oct 2014

New screening tools detect heart and lung disease

Two Michigan high school students, sisters Ilina and Medha Krishen, have developed screening tools using electronic stethoscopes to detect lung and heart disease.

21 Oct 2014

Sanofi, MyoKardia partner to develop targeted therapeutics for cardiomyopathies

Sanofi and MyoKardia, Inc., a privately-held company leading the development of precision therapies for genetic heart disease, announced today a worldwide collaboration to discover and develop first-of-its-kind targeted therapeutics for heritable heart diseases known as cardiomyopathies, the most common forms of heart muscle disease.

18 Sep 2014

Myosin binding protein C holds the key to new treatments for heart disease

Loyola University Chicago recently hosted a meeting of more than 60 of the world's leading researchers of a protein that could hold the key to new treatments for heart disease.

25 Jun 2014

European screening guidelines lead to potential false disqualification of black athletes

A new study by researchers at St George's, University of London published in the journal Circulation has found that current European screening guidelines used by sports organisations to detect heart abnormalities lead to over-investigation and potential false disqualification of black athletes with perfectly healthy hearts.

1 Apr 2014

Study of astronauts show heart becomes more spherical when exposed to microgravity in space

New findings from a study of 12 astronauts show the heart becomes more spherical when exposed to long periods of microgravity in space, a change that could lead to cardiac problems, according to research to be presented at the American College of Cardiology's 63rd Annual Scientific Session.

31 Mar 2014

Researchers find new drug compound that treats laboratory mice with congenital heart disease

Congenital heart disease is the most common form of birth defect, affecting one out of every 125 babies, according to the National Institutes of Health. Researchers from the University of Missouri recently found success using a drug to treat laboratory mice with one form of congenital heart disease, hypertrophic cardiomyopathy - a weakening of the heart caused by abnormally thick muscle.

23 Feb 2014

Focused ultrasound exam may accurately identify athletes with heart problems

A young athlete in seemingly excellent health dies suddenly from a previously undetected cardiovascular condition such as hypertrophic cardiomyopathy in nearly every U.S. state annually.

25 Jan 2014

Focused ultrasound exam accurately identifies heart problems in athletes

A young athlete in seemingly excellent health dies suddenly from a previously undetected cardiovascular condition such as hypertrophic cardiomyopathy in nearly every U.S. state annually.

24 Jan 2014

Multiplicom launches MID kit for Illumina MiSeq and MASTR kits for MODY, ADH and HCM

Multiplicom NV, a specialist in the development, production and commercialization of innovative molecular genetic tests based on massively parallel sequencing, today announces that it is launching a CE/IVD labeled MID kit for Illumina MiSeq together with three new germline mutation detection MASTRTM kits enabling the identification of individuals at risk for maturity onset diabetes of the young, autosomal dominant hypercholesterolemia, and hypertrophic cardiomyopathy.

2 Dec 2013

CDC and NIH collaborate to create Sudden Death in Young Registry

A registry of deaths in young people from conditions such as heart disease and epilepsy is being created to help researchers define the scope of the problem and set future research priorities. The National Institutes of Health and the Centers for Disease Control and Prevention are collaborating to create the Sudden Death in the Young Registry.

24 Oct 2013

Deficiency of antioxidant response protein prevents hypertrophic cardiomyopathy

University of Utah researchers have found that deficiency of an antioxidant response protein called nuclear erythroid-2 like factor-2 (Nrf2) delays or prevents hypertrophic cardiomyopathy, a type of a heart failure in which the heart muscle grows abnormally thick.

12 Oct 2013

Four new pre-clinical drug development projects at NIH develop treatment for rare disease

Four new pre-clinical drug development projects at the National Institutes of Health will target a form of blindness and diseases characterized by cardiac problems. The projects were selected for their potential to treat specific rare diseases and to help scientists uncover new information that can be shared with other researchers.

13 Sep 2013

Study: Death risk is greatest for those who developed hypertrophic cardiomyopathy in childhood

A long-term study of children with a complex heart condition called hypertrophic cardiomyopathy (HCM) found that the risk of death or need for immediate listing for heart transplantation was greatest for those who developed this disease as infants with congestive heart failure and for children who also had selective inborn errors of metabolism, a group of rare genetic disorders in which one or more of the body's key metabolic processes are disrupted.

5 Sep 2013

US scientists identify risk factors for pediatric hypertrophic cardiomyopathy

US scientists have identified key risk factors that predict which children with hypertrophic cardiomyopathy, the most common cause of sudden death in young people, are at greatest risk of death or need for heart transplant—information that could help physicians figure out who will benefit most from transplant surgery.

4 Sep 2013